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Biomedical subjects

K G Wiese

Publications and source records attributed to K G Wiese.

11 recordsLinked to original sources
PubMed1994

[Electrolyte concentration, real and osmotic pressure in abscesses].

Electrolyte concentrations, osmotic and hydrostatic pressures of 26 abscesses in the head and neck area were measured. As the main cations Sodium (138 +/- 38 mmol/l) and Potassium (37 +/- 16 mmol/l and as anions Chloride (183 +/- 46 mmol/l) and Bicarbonate (10 +/- 4 mmol/l) were identified. The pH-value of the pus liquid decreased to 6.164 +/- 0.233. The calculated mean osmotic pressure of the pus liquid was 7910 +/- 1455 mm Hg whereas the measured physical pressure inside the abscess was 49 +/- 13 mm Hg. As a consequence of being an osmotically active system the inactivity of antibiotics in abscesses may be explained by a lack of diffusion through the abscess membrane, due to electrochemical charges or the size of the molecule, or by lack or reduction of the capillary perfusion and ultrafiltration rate due to physical pressure of the abscesses on perifocal blood vessels.

Abscess↗
PubMed1993

The role of the periosteum in osteointegration of hydroxyapatite granules.

The role of the periosteum in the osteointegration of hydroxyapatite (HA) granules was studied in the skull and tibial bone of eight adult Göttingen minipigs. Calcein and tetracycline were used as labeling stains to determine new bone formation. Depending on the condition of the periosteum, three different patterns of osteointegration of HA were found.

Animals↗
PubMed1993

The effect of lidocaine on growth of cells of head and neck squamous cell carcinoma.

The effect of lidocaine on the growth rate of human squamous cell carcinoma of the head and neck area was investigated in tissue culture. As growth parameters, the mean cell area, the total cell area, the field area and the total number of cells have been measured by digital image analysis. The carcinoma's two cell types--round and spindle--were recorded separately to verify different patterns of alteration. All parameters did not decrease significantly when lidocaine was given as a single dose prior to the culture. A significant decrease (p < 0.05) at day 6, 9 and 12 in culture was found when lidocaine (7 micrograms ml-1) was added to the culture medium.

Carcinoma, Squamous Cell↗
PubMed1993

Osmotically induced tissue expansion with hydrogels: a new dimension in tissue expansion? A preliminary report.

The possibility of using an osmotically-driven system for effective tissue expansion has been verified. As a biocompatible and efficient system, a copolymer of methylmethacrylate and vinylpyrrolidone is used in animal research (rats). This hydrogel was able to generate, in vitro, a physical swelling pressure of approximately 235 mm Hg. The range of possible volume expansion in solutions of differing concentrations was 3 to 30 times its water-free gel form. In animal experiments a high biocompatibility and efficiency in tissue expansion can be observed.

Animals↗
PubMed1993

[Symmetry of the human midface].

A new measuring instrument called "zygometer" is introduced. This device provides a simple technique for measuring the position of the zygomatic bone and arch allowing for lateral comparison. Standard measurements of the midface were collected from 250 uninjured test subjects. In 80% of the cases a symmetry of up to 2 mm was determined. The research results are presented and discussed with reference to clinical application.

Animals↗
PubMed1993

Measurement of the midface symmetry in trauma and reconstructive surgery.

The pre- and intraoperative determination of the midface symmetry during the management of trauma or reconstructive surgery cases may be difficult due to swelling of the covering tissue. To handle these problems, a new apparatus, called "Zygometer", is introduced. This instrument is able to measure the position of the midface bones and enables a comparison with the controlateral side. The results of a study with 250 persons to get standard measurements for symmetry and asymmetry are presented and discussed. Indications and clinical application of the zygometer are demonstrated.

Adult↗
PubMed1989

[Reconstruction of atrophied jaw segments using individually configured hydroxyapatite vicryl mesh grafts. Experimental animal studies and clinical case reports].

Individually configurated vicryl mesh sleeves permit the production of unusual implant shapes for the reconstruction of atrophied jaw segments. The experimental animal studies have shown that the vicryl mesh sleeve does not interfer with the bony integration of the implanted HA ceramics. The formation of a ceramoosseous regenerate is limited to the vicinity of the bony implant bed.

Adult↗