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Biomedical subjects

K G Odde

Publications and source records attributed to K G Odde.

At least 37 records · Page 2Linked to original sources

Costs of veterinary services and vaccines/drugs used for prevention and treatment of diseases in 86 Colorado cow-calf operations participating in the National Animal Health Monitoring System (1986-1988).

Eighty-six cow-calf operations involved in the Colorado National Animal Health Monitoring System were monitored for a 12-month period, and data were collected on the incidence, prevention, and costs of disease. The costs of veterinary services and vaccines/drugs used in the treatment and prevention of disease conditions in these beef herds were determined and expressed on a per cow basis. Beef producers in this study spent an average of $2.04 ($0 to $29.88) per cow annually on veterinary services for treatment of disease conditions. The cost of veterinary services was a relatively small percentage (5.4%) of the total mean cost of disease incidence. The reproductive tract disease class was the most costly class in terms of veterinary services for disease treatment ($0.99/cow). Dystocia was the disease condition with the largest veterinary treatment cost. The total mean annual cost of drugs used in the treatment of disease conditions was $1.22/cow. The enteric, miscellaneous, and respiratory tract disease classes had similar mean drug costs for disease treatment and ranged from $0.31 to $0.39/cow. The total mean annual cost of veterinary services for administration of preventive measures in these herds was $1.85/cow ($0 to $12.03). Pregnancy examination, breeding soundness examination in bulls, brucellosis vaccination, pulmonary arterial pressure test, and campylobacteriosis vaccination accounted for over 90% of the money spent for preventive veterinary services. Approximately 60% of the total mean annual disease prevention cost was attributed to the purchase of vaccines/drugs ($6.59/cow).(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

Annual disease incidence in Colorado cow-calf herds participating in rounds 2 and 3 of the National Animal Health Monitoring System from 1986 to 1988.

Thirty-nine and 47 randomly selected Colorado cow-calf operations participated in the National Animal Health Monitoring System (NAHMS) during rounds 2 (October 1986 to September 1987) and 3 (October 1987 to September 1988), respectively. Data on the incidence of disease conditions within each herd were collected by federal and state Veterinary Medical Officers and university veterinarians through monthly visits to the ranches. Annual disease incidence for disease classes and the most frequently reported individual disease conditions were determined and expressed on a per 100 cow basis. The mean annual disease incidences for all diseases in these herds were 48.8 and 47.7 new cases per 100 cows for rounds 2 and 3, respectively. The ranges for herd annual disease incidence were wide in both study years. The enteric disease class had the highest mean annual disease incidence in both years of the study, and this was primarily because of diarrhea of unknown cause in calves. Diarrhea of unknown cause accounted for approximately 25% of all new disease cases in both rounds of the study. The mean annual disease incidences were not different for any disease class between the two rounds. The data indicate that, on the average, diarrhea of unknown cause, pneumonia, dystocia, foot rot (interdigital necrobacillosis), pinkeye (infectious keratoconjunctivitis), respiratory tract infection, death of unknown cause, and nonpregnancy had the highest incidences in these Colorado beef herds during the study period. However, because of the wide variation of the predominant disease problems between herds, a herd's disease history as well as the common disease problems in the geographic area of a herd must be considered in designing a herd health program.

Animals↗

Annual costs associated with disease incidence and prevention in Colorado cow-calf herds participating in rounds 2 and 3 of the National Animal Health Monitoring System from 1986 to 1988.

Thirty-nine and 47 randomly selected Colorado cow-calf operations were monitored for health events and their associated costs during rounds 2 and 3, respectively, of the National Animal Health Monitoring System (NAHMS). Data were collected from each operation for a one-year period by NAHMS veterinarians through monthly interviews, and the costs associated with the incidence and prevention of disease conditions were determined and expressed on a per cow basis. The beef producers involved in this study spent an average of $32.75 per cow in round 2 and $40.97 per cow in round 3 on an annual basis for the treatment of disease conditions. These costs were not different between the 2 rounds because of the wide ranges in the individual herd costs for disease incidence in each round. In both years of the study, the largest contributor to the total mean annual cost of disease incidence was the cost of death of diseased animals, and this cost accounted for approximately two-thirds of the total mean annual cost in each round. The total mean annual costs of disease prevention in these herds were $11.24 and $11.19 per cow in rounds 2 and 3, respectively. There were wide ranges in both rounds in the amounts of money spent per cow by individual herds for disease prevention. The largest individual cost of disease prevention in each year was the cost of vaccines/drugs, whereas the smallest individual cost in each round was the cost of veterinary services.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

Arterial blood sample collection from the newborn calf.

Measurements of arterial blood gas tensions and acid-base status provide a means of assessing how well the respiratory system is functioning. This information is essential for thorough evaluation of a compromised neonatal calf but arterial blood sampling is difficult immediately after birth. A technique for collecting blood from the brachial artery of the newborn calf is described. This technique, which uses an easily located site, has been successfully used in field studies to determine arterial blood gas values in such calves.

Animals↗

Hypertrophy and hyperplasia of bovine fetal tissues during development: fetal liver insulin-like growth factor I mRNA expression.

Tissue growth of crossbred fetal beef calves was examined by measuring RNA, DNA, and protein concentrations in liver, heart, and biceps femoris. Furthermore, liver insulin-like growth factor I (IGF-I) mRNA expression and mRNA species size during fetal development was observed. Tissue samples were collected from six fetuses every 42 d of gestation, from d 106 to d 274. In the liver, protein and DNA concentrations decreased, whereas RNA levels remained constant throughout fetal growth. The RNA/DNA and protein/DNA ratios in liver increased with fetal age. Heart DNA and RNA levels decreased, whereas protein concentration and protein/DNA ratios increased with fetal age. Protein and protein/DNA ratios decreased in biceps tissue, whereas DNA and RNA concentrations were constant. IGF-I mRNA was seen at 4.4, 2.5, and 1.2 kb in adult and 4.4, 2.5, and 1.7 kb in fetal bovine liver. Relative expression of liver IGF-I mRNA did not vary during fetal development. The current study shows that during the last 2 and 3 mo of gestation, heart and liver were undergoing hypertrophic growth, whereas biceps tissue did not exhibit the same trend. Elevated ratios of RNA and protein to DNA in liver above that of the heart and biceps suggest extensive hepatic cellular hypertrophy as well as increased transcriptional and translational activity. Insulin-like growth factor I mRNA levels were not related to the changes in RNA, DNA, and protein seen in hepatic tissue.

Animals↗

A review of synchronization of estrus in postpartum cattle.

Estrus has been synchronized in cattle with progestogens, prostaglandins (prostaglandin F2 alpha and its analogues), progestogen-estrogen combinations and progestogen-prostaglandin combinations. Progestogens administered for 14 to 20 d are effective in synchronizing estrus; however, fertility at the synchronized estrus is subnormal. Duration of progestogen treatment can be reduced by combining it with an estrogen. Syncro-Mate B is a progestogen-estrogen combination that results in a tightly synchronized estrous response. Prostaglandins can be used in double- or single-injection programs. Fertility of the estrus after prostaglandin treatment is similar to that of controls. Estrus also has been synchronized effectively by combining a 5- to 9-d progestogen treatment with prostaglandin at or near the end of treatment. When prostaglandin is used alone, cattle in the late stages of the luteal phase (d 11 to 15 of the estrous cycle) at the time of prostaglandin injection have a higher estrous response and may be more fertile than those injected with prostaglandin in the early part (d 6 to 9) of the luteal phase. More recently, a 14-d progestogen treatment has been combined with a prostaglandin injection given 16 to 18 d after progestogen withdrawal. This system places cattle in the late luteal phase of the estrous cycle at the time of prostaglandin injection and has resulted in an estrus with greater fertility than that immediately following progestogen treatment.

Animals↗

Management practices and their association with reproductive health and performance in Colorado beef herds.

An observational study was conducted to quantify the effects of management practices on reproductive performance and disorders of beef cows. The study population consisted of 44 randomly selected Colorado cow-calf herds monitored for disease and reproductive events as part of the National Animal Health Monitoring System. The managers of the herds were surveyed with a standardized questionnaire to determine specific management characteristics of their operations. Data were analyzed using the random-effects multiple logistic regression model. Outcomes of interest were calving rate, herd incidence rates of dystocia and combined reproductive disorders, and calf mortality rate. A higher calving rate was associated (P less than .01) with a decreased percentage of replacement females in the herd, a shorter breeding season, a smaller herd size, and a lower percentage of bulls being used as yearlings. Incidence rates of both dystocia and combined reproductive disorders were found to be lower (P less than .01) in herds that were fed cottonseed cake as a winter supplement, but higher (P less than .01) in herds that were fed grass hay as a winter supplement. Herds located in the mountains of Colorado had lower (P less than .01) incidence rates of dystocia and reproductive disorders than herds located in the eastern plains. Calf mortality rate was found to be higher (P less than .05) with calving seasons that began earlier in the year. Higher calf mortality rates were associated (P less than .05) with an increased incidence of dystocia, the commingling of cattle on summer range, and smaller herd size.

Animal Feed↗

Development of preovulatory follicles expected to form short-lived corpora lutea in beef cows.

Oestrus, expected to be followed by a short luteal phase, was induced in post-partum cows by weaning their calves at 35 days after parturition. Ovaries containing the first preovulatory follicles (Type F) formed after parturition were collected 3 h after the onset of oestrus. For comparison, preovulatory follicles (Type C) were collected 3 h after the onset of oestrus in normally cycling cows. The number of granulosa cells was determined and the concentrations of receptors for follicle-stimulating hormone (FSH) and luteinizing hormone (LH) in granulosa cells and for LH in theca cells were measured. Concentrations of oestradiol-17 beta, testosterone, androstenedione and progesterone in follicular fluid were also measured. Type F follicles contained about twice the number of granulosa cells (based on DNA) as did Type C follicles (45.8 +/- 11.3 and 24.5 +/- 3.9 micrograms DNA/follicle, respectively; P less than 0.05) but these cells had fewer receptors for LH (0.13 +/- 0.02 vs 0.29 +/- 0.03 fmol/micrograms DNA; P less than 0.01) and FSH (0.61 +/- 0.08 vs 1.3 +/- 0.29 fmol/micrograms DNA; P less than 0.08) than did those from Type C follicles. Additionally, there were fewer receptors for LH in theca tissue from Type F than from Type C follicles (28.3 +/- 5.2 vs 51.3 +/- 6.1 fmol/follicle; P less than 0.01). Concentrations of oestradiol-17 beta (475.8 +/- 85.6 vs 112.9 +/- 40.0 ng/ml; P less than 0.01) and androstenedione (214.1 +/- 48.7 vs 24.7 +/- 7.7 ng/ml; P less than 0.01) in follicular fluid were higher in Type C than in Type F follicles.(ABSTRACT TRUNCATED AT 250 WORDS)

Androstenedione↗

Comparison of Melengestrol Acetate-Prostaglandin F(2)alpha to Syncro-Mate B for estrus synchronization in beef heifers.

Three hundred and ten yearling heifers of various breeds were used in five trials to compare two estrus synchronization treatments. Treatment 1 consisted of Melengestrol Acetate-Prostaglandin F(2)alpha (MGA-PGF(2)alpha). Heifers were fed 0.5 mg MGA/head/d for 14 to 16 d. Sixteen or 17 d after the final MGA feeding, heifers were injected i.m. with 25 mg PGF(2)alpha. Treatment 2 consisted of Syncro-Mate B (SMB). Heifers were given a 9-d norgestomet implant plus an injection containing 3 mg norgestomet and 5 mg estradiol valerate i.m. at implant insertion. Heifers were observed for estrus at 6-h intervals for 120 h after the end of treatments and were artificially inseminated 12 to 18 h after observed estrus. Heifers synchronized with MGA-PGF(2)alpha and SMB had a similar (P > 0.10) estrous response (83.4 vs 90.2%) and a similar (P > 0.10) degree of synchrony (71.8 vs 79.0%) following treatment. However, the synchronized conception rate (68.7 vs 40.6%) and the synchronized pregnancy rate (57.3 vs 36.6%) were higher (P < 0.01) in MGA-PGF(2)alpha than SMB heifers. Breeding season pregnancy rates were similar in both treatment groups. Heifers in both groups that were classified as cycling prior to initiation of treatment had improved reproductive performance following synchronization compared with those classified as noncycling. Based on higher synchronized conception and pregnancy rates and lower labor requirements and drug costs, the MGA-PGF(2)alpha system appears to be a better method to synchronize estrus in beef heifers than the SMB system.

Journal Article↗

Synchronization of estrus in beef cows with Norgestomet-Alfaprostol or Syncro-Mate B.

In the spring of 1986, 506 beef cows were used to evaluate the effectiveness of two estrus synchronization systems. Cows were synchronized with either a 6-mg Norgestomet implant placed in the ear for 14 d followed by a 6-mg Alfaprostol injection given 16 d after implant removal (Norgestomet-Alfaprostol) or with Syncro-Mate B (6-mg Norgestomet implant for 9 d with an injection containing 5 mg estradiol valerate and 3 mg Norgestomet at the time of implantation). The Alfaprostol injection in the Norgestomet-Alfaprostol group was given the same day as implant removal in the Syncro-Mate B group. These treatment groups were compared to a group of untreated controls. Cows were allotted to treatments by days postpartum, age and breed. Syncro-Mate B cows had a higher estrous response within 5 d after treatment (78.6 vs 64.0%) and a shorter interval to estrus (39.2 vs 66.7 h) than did Norgestomet-Alfaprostol cows (P < 0.05). Controls had a significantly lower estrous response compared to either of the synchronized groups (27.1%). The degree of estrus synchrony was identical in both synchronization systems (72.7%). Synchronized conception rate tended to be higher (P = 0.06) in the Norgestomet-Alfaprostol cows than in the Syncro-Mate B cows (74.5 vs 62.5%). Synchronized, 21-d, 25-d and breeding season pregnancy rates were 51.2, 70.8, 76.8 and 92.9% for Norgestomet-Alfaprostol cows; 48.5, 63.0, 73.2 and 87.8% for Syncro-Mate B cows; and 15.6, 56.3, 61.3 and 86.9% for control cows. The four pregnancy rates were not different between the two synchronization treatments (P > 0.10). Controls had lower synchronized and 25-d pregnancy rates when compared to either of the synchronized groups (P < 0.05). Days postpartum had no effect on the reproductive performance of cows synchronized with Norgestomet-Alfaprostol. Our results indicate that the Norgestomet-Alfaprostol system is as effective as Syncro-Mate B in synchronizing estrus in beef cows.

Journal Article↗

Survival of the neonatal calf.

Factors that influence passive transfer of immunoglobulins from colostrum to the calf include timing of colostrum intake, immunoglobulin concentration of the colostrum, presence of the dam, season, and individual calf variation in efficiency of absorption. This article describes a study conducted to determine the effect of body condition at calving and calving difficulty on calf vigor and calf serum immunoglobulin concentrations, and to determine the relationship of calf serum immunoglobulin concentration and calf growth at weaning.

Animals↗

Validation of a heterologous radioimmunoassay for insulin-like growth factor-I in bovine serum.

A quantitative, repeatable, heterologous radioimmunoassay (RIA) for insulin-like growth factor-I (IGF-I) was developed for bovine serum. Untreated serum could not be assayed due to interference by IGF-I-binding protein. Serum acidified to pH 3.6 in glycine-HCl (0.1 mol/l) for 24 h at 37 degrees C and neutralized with NaOH produced inhibition curves non-parallel to the [Thr59]-IGF-I standard. Neutralization by 40-fold dilution of acidified serum samples with assay buffer produced inhibition curves nearly parallel to the IGF-I standard. Complete parallelism was achieved by utilizing preprecipitated normal rabbit serum-sheep anti-rabbit gamma-globulin to separate antibody-bound 125I-labelled IGF-I from free 125I-labelled IGF-I. Recovery of IGF-I (1.3-52.3 fmol) added to serum was quantitative. The sensitivity of the RIA (n = 6) was 8.25 +/- 0.17 (S.E.M.) fmol. Intra- and interassay coefficients of variation were 3.03 and 4.95% respectively. Serum IGF-I levels measured in beef calves at weaning were positively correlated with weaning weight, total weight gain from birth to weaning and average daily weight gain. In conclusion, a heterologous RIA for IGF-I in beef serum which is sensitive, accurate, precise and repeatable has been developed.

Animals↗

Serum insulin-like growth factor I profiles in beef heifers with single and twin pregnancies.

Serum samples and BW were obtained from 2-yr-old beef heifers, pregnancy with either single (SF, n = 12) or twin (TF, n = 7) fetuses, at 7-d intervals from d 190 of gestation until calving. Serum insulin-like growth factor I (IGF-I) concentrations of SF heifers gradually declined from d 190 (69.9 +/- 1.0 ng/ml) to d 263 (55.6 +/- .8 ng/ml), then exhibited a slight increase by d 277 (63.4 +/- 1.1 ng/ml). Serum IGF-I concentrations of TF heifers essentially paralleled, yet were lower (P less than .05) than, concentrations in SF heifers for all days tested except d 197 and 205. The SF heifers pregnant with heifer fetuses (n = 6) had higher IGF-I concentrations (P less than .1) than heifers pregnant with bull fetuses (n = 6) for all days tested except d 214 and 235. Instantaneous absolute growth rate (IGR) of SF heifers declined from 1.485 kg/d at d 190 to .257 kg/d by d 277. Rate of decline in IGR of TF heifers was much greater (P less than .0001). Correlations between serum IGF-I concentrations and IGR for SF and TF heifers were .79 (P less than .001) and .59 (P less than .05), respectively. These data suggest that number and sex of fetus influence maternal concentrations of IGF-I and that the combined growth rate of the dam and conceptus during gestation is related to serum IGF-I concentration.

Animals↗

Effects of prepartum protein nutrition and birth weight on basal metabolism in bovine neonates.

Recipient beef heifers, pregnant with single demi-embryos, were paired to according to identical twin or full-sib embryo. Within pair, recipient heifers were assigned to one of two isocaloric diets containing a control or restricted level of protein (91 vs 55% of National Research Council recommendations) on d 190 of gestation. Following parturition, calves were weighed, fed 1 liter of colostrum, dried and placed in a metabolic chamber at 5 h of age for an 8-h determination of heat production (HP). Maternal body weight gains (P less than .001) during the last trimester and body condition scores at parturition (P less than .05) were reduced in heifers fed the protein-restricted diet. Calves born to heifers fed the protein-restricted diet had 11.4% lower (P less than .05) HP than calves born to control heifers (43.7 vs 49.3 kcal.kg-1.d-1). Birth weights, respiratory quotients and rectal temperatures of newborn calves were not significantly affected by prepartum protein restriction. Within treatment groups, the relationship between HP and weight was described by the equation: HP (kcal/d) = 2.30 wt1.86. The allometric exponent of 1.86 +/- .26 implied that weight-specific metabolic rate was higher rather than lower in larger weight calves. We concluded that the thermogenic ability of neonatal calves may be compromised by prepartum protein restriction and(or) small birth weights.

Animal Nutritional Physiological Phenomena↗

Synchronization of estrus in embryo transfer recipients receiving demi-embryos with Syncro-Mate B or estrumate.

One hundred thirty-five crossbred heifers were used to compare the effectiveness of Estrumate and Syncro-Mate B in synchronizing estrus in recipient heifers for transfer of demi-embryos. A higher percentage (P<0.01) of Syncro-Mate B heifers showed estrus within 5 d following treatment than did Estrumate heifers (100.0 vs 85.1%). Demi-embryos were transferred to 41 and 26 heifers treated with Syncro-Mate B and Estrumate, respectively. The pregnancy rate of heifers synchronized with Estrumate was higher (P<0.01) than that of heifers synchronized with Syncro-Mate B (64.3 vs 27.8%). A single blood sample was collected on the day of embryo transfer from all heifers receiving demi-embryos, and progesterone concentration was determined. There were no significant differences in mean serum progesterone concentrations either between heifers synchronized with Syncro-Mate B and Estrumate or between pregnant and open heifers within synchronization treatment. There was no relationship between serum progesterone concentration and pregnancy rate in the Estrumate recipients (P>0.10). However, 25.0% of the Syncro-Mate B recipients had serum progesterone levels <1.00 ng/ml, and these heifers had a lower pregnancy rate (P<0.05) than Syncro-Mate B heifers with serum progesterone levels between 1.00 to 3.00 ng/ml. It appears that the Syncro-Mate B heifers with <1.00 ng/ml progesterone had either a delay in corpora lutea function or a continuously reduced concentration of serum progesterone which altered the uterine environment of these heifers and caused the lower pregnancy rate in the Syncro-Mate B group. Based on the large difference in pregnancy rates, Estrumate appears to be a more effective method to synchronize estrus in recipient heifers receiving demi-embryos.

Journal Article↗

Effect of forty-eight-hour calf removal, once- or twice-daily suckling and Norgestomet on beef cow and calf performance.

Trials were conducted in 1980 and 1981 to evaluate the effects of once-daily suckling, twice-daily suckling, 48-h calf removal, and Norgestomet on performance of spring-calving cows and their calves. Eighty-three and 73 Polled Hereford and 29 and 42 Simmental-cross cows were utilized in 1980 and 1981, respectively. Cows were allotted by age, breed, calving date and winter nutrition treatment to one of four groups: 1) once-daily suckle for 24 d starting 11 d before the beginning of the breeding season, 2) twice-daily suckle (same time frame as 1), 3) 48-h calf removal ending immediately before the breeding season, 4) calves remained with cows (controls). One-half.of each group was implanted with Norgestomet from 11 until 2 d before the start of the breeding season. Once- and twice-daily suckling increased (P<0.05) the percentage of noncycling cows showing estrus the first 3 wk after the start of treatment. Pregnancy rates for the breeding season were higher (P<0.1) in the once-daily suckle and 48-h calf removal groups for cows that had not exhibited estrus before the beginning of treatment. Norgestomet increased (P<0.05) the percentage of cows showing estrus within 3 wk after the start of treatment within the 48-h calf-removal and control groups. Milk production was not affected (P>0.1) by suckling treatment. Calf weight gains during suckling treatment were greater (P<0.05) in control and twice-daily suckled calves than in 48-h calf removal or once-daily suckled calves. Suckling treatment did not affect (P>0.1) adjusted weaning weights of calves or frequency and duration of suckling recorded 2 wk after the end of suckling treatment.

Journal Article↗

Suckling behavior in range beef calves.

The number and duration of suckling incidences were recorded during eight 24-h observation periods in a herd of spring-calving Polled Hereford and percentage Simmental cows in 1980 and 1981. The average number of suckling events per calf in 24 h was 5.0 +/- .1 and the average time spent suckling in 24 h was 46 +/- 1 min. Peaks in suckling activity occurred from 0500 to 0700, 1000 to 1300 and 1700 to 2100 h. The most suckling events in a single hour occurred between 0500 and 0600 h and the least between 2200 and 2300 h. Day of the estrous cycle did not influence the number or duration of suckling events. Cows that gave more milk nursed less frequently and heavier calves suckled less frequently (P less than .01). Age, breed and sex of the calf did not influence (P greater than .1) suckling frequency or duration.

Age Factors↗