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Biomedical subjects

K Fukutani

Publications and source records attributed to K Fukutani.

81 records · Page 5Linked to original sources

New trial for fiberoptic cystourethroscopy: the use of metal sheath.

To overcome the disadvantages of using the fiberscope to observe the lower urinary tract we devised a metal sheath, which is used in combination with the fiberoptic cystourethroscope. The metal sheath helps in a smooth introduction of the fiberscope through the urethra and also in a close approximation of the fiberscope to the lesion. Fiberoptic cystourethroscopes combined with the metal sheath are useful in observing the bladder neck, the pedicle of tumors, the inner surface of the diverticulum and the condition of the intestine anastomosed with the bladder, which the current rigid endoscopes cannot approach. Photographs of the lower urinary tract were easily taken with this metal sheath method. However, the fiberoptic cystourethroscopes have a much smaller field of view, lower resolution and mor obscurity in the view. These drawbacks should be improved in the future.

Cystoscopes↗

Effect of aminophylline injection on the pituitary-thyroid axis in asthmatics.

We investigated the effect of aminophylline on the pituitary-thyroid axis in 13 asthmatics (21-71 yr). Aminophylline (250 mg), dissolved in 100 ml of saline, was given intravenously for 30 min. Blood was collected, before and 30, 60 and 120 min after beginning the injection. Serum TSH was significantly increased from the 2.2 +/- 1.6 microU/ml baseline to 2.7 +/- 1.9 microU/ml at 60 min (p less than 0.01), and to 2.8 +/- 2.1 microU/ml at 120 min (p less than 0.05). Serum T4 also rose from the 8.8 +/- 1.2 micrograms/dl baseline to 9.6 +/- 1.5 micrograms/dl at 120 min (p less than 0.05). There were no changes in serum T3 and rT3 levels. Correlations between increase of theophylline and TSH levels, and between increases in TSH and T4 concentrations, were observed. Since aminophylline stimulates the secretions of catecholamine from the sympathetic nerve endings and the adrenal medulla, we assumed that TRH was released from the hypothalamus by a beta-2-receptor mechanism because TSH secretion had been stimulated. These findings suggested that aminophylline-induced T4 release from the thyroid is mediated by released TSH and by the direct stimulatory effects of raised endogenous catecholamine on the thyroid.

Adult↗