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Biomedical subjects

K Fritz

Publications and source records attributed to K Fritz.

At least 55 records · Page 3Linked to original sources

[The cartilaginous crooked nose in the no-man's land between specialty disciplines (thoughts and observations from a rhinosurgical practice)].

The surgery of the cartilaginous twisted nose as an extension of septal surgery into the external nose is not as generally integrated in the teaching programme of rhinology as daily practice would require. On the other hand, plastic surgery--considering itself as a speciality of its own--has not yet entered into the full complexity of inner nose surgery, a major component of twisted nose correction.

Cartilage↗

[Determination of alkali resistance by skin patch testing].

298 patients suffering from eczema were tested for alkali-resistance by means of the method according to Burckhardt-Locher (ARBL) as well as patch-testing. If ARBL revealed decreased alkali-resistance, there was a high correlation with the outcome of the patch-test of alkalis. If ARBL showed normal values, however, additional patch-testing detected reduced alkali-resistance in 42.9% of the cases. In order to make a well-founded diagnosis of alkali-resistance, we suggest to combine both methods and/or to include a control of ARBL after 24 hours as proposed by Burckhardt.

Adolescent↗

Sperm parameters and ejaculation before and after operative treatment of patients with germ-cell testicular cancer.

In testicular tumor patients, the stage of disease is most accurately determined by retroperitoneal lymph node dissection (RLND) and histologic examination of the operative specimen. The resection of possibly metastatic nodes is essential for securing a good prognosis. However, the most frequently encountered loss of ejaculatory function is a major disadvantage of radical RLND. In patients who intraoperatively proved to be free of metastases, we successfully employed a modified technique aiming at the preservation of sympathetic nerve fibers which mediate ejaculation. In 29 of 37 patients (78%), postoperative ejaculation was antegrade. It was retrograde in 5 of 37 patients (13.5%); 3 patients had no emission. These results are retrospectively compared with results of radical RLND in 87 patients of whom 64% suffered a total loss of ejaculation and only 23% had antegrade ejaculation. RLND did not affect sperm count, motility, and cell morphology. Potentia coeundi was preserved in all cases, although 27% of patients experienced diminished erectility or libido.

Adolescent↗

[Behavior of the hypophyseal-adrenal cortex system in inhalation and conduction anesthesia. A review with comparative study].

The effects of halothane anaesthesia or epidural analgesia on the per- and postoperative change in blood concentrations of ACTH, beta-lipotropin, cortisol, dehydroepiandrosterone, aldosterone, glucose, lactate and free fatty acids were investigated in connection with elective orthopaedic surgery. Anaesthesia in man with halothane and nitrous oxide was found to be associated with a significant increase in plasma ACTH levels and beta-LPH levels. Changes in plasma dehydroepiandrosterone were similar to those in plasma cortisol. The elevation of plasma aldosterone during major surgery could be explained as the effect of an increased renin secretion. However, simultaneous increase in plasma cortisol and plasma aldosterone during surgery reflect an additional effect of adrenocorticotropin upon aldosterone secretion.

Adrenal Cortex↗

[Suppression of the adrenal cortex by infusion of etomidate in general anesthesia].

The effects of anaesthesia with fentanyl and prolonged etomidate infusion (0.8 mg/kg/h) on the peroperative and postoperative change in blood concentrations of aldosterone, cortisol, dehydroepiandrosterone, ACTH, epinephrine, norepinephrine, dopamine, glucose, lactate and free fatty acids (FFA) were investigated in connection with major abdominal surgery. During surgery and anaesthesia with prolonged etomidate infusion no significant alterations in plasma catecholamine concentrations were observed. In contrast, basal plasma levels of ACTH (20.0 +/- 9.5 pg/ml----352.8 +/- 150.8 pg/ml) were elevated in all patients. Despite this endogenous ACTH stimulus, aldosterone (121.8 +/- 19.4 pg/ml----58.4 +/- 10.4 pg/ml) and cortisol (12.3 +/- 2.84 micrograms/dl----5.79 +/- 1.2 micrograms/dl) and dehydroepiandrosterone (2.28 +/- 1.09 ng/ml----1.27 +/- 0.25 ng/ml) levels were markedly depressed in every patient during the perioperative period. Twenty-four hours after surgery the basal steroid values were within or above normal limits.

Abdomen↗

[Effect of tramadol on ventilatory CO2 response and mouth occlusion pressure].

The respiratory depressant effects of 1.0 and 1.5 mg/kg of tramadol were studied in 14 healthy young persons by determining the CO2 response (Read's method) and the mouth occlusion pressure (Whitelaw's method) before and 10, 30 and 60 min after administration of the drug. The decrease in minute volume VE (PACO2 = 55 mmHg), dependent on dose, ranged between 11,2 and 17,8%. The mean ventilatory response to CO2 decreased after administration of 1.0 and 1.5 mg/kg of tramadol by 15.4 and 25.4% respectively of the normal value. In the same patients, the mouth occlusion pressure responses decreased by 16.1 and 25.6% respectively. There were no significant changes in mean inspiratory flow rate (determined from tidal volume and averaged time of inspiration). These findings demonstrate that tramadol, in contrast to morphine, produces less depression of the ventilatory responses to CO2 in healthy subjects.

Adult↗

[Endocrine reaction pattern in abdominal surgical patients as affected by isoflurane anesthesia].

The effects of isoflurane anaesthesia on the per- and postoperative change in blood concentrations of aldosterone, cortisol, dehydroepiandrosterone, insulin, prolactin, thyroxine, t3-uptake, epinephrine, norepinephrine, dopamine, glucose, FFS, lactate, and pyruvate were investigated in connection with major abdominal surgery. Contrary to prolactin levels (8.42 +/- 1.71 ng/ml----46.25 +/- 6.78 ng/ml; p less than 0.001) the plasma concentrations of the adrenal steroids aldosterone, cortisol, and dehydroepiandrosterone sank initially after induction of anaesthesia with thiopentone. However, after skin incision the levels of aldosterone (49.9 +/- 11.6 pg/ml----202.1 +/- 57.6 pg/ml; p less than 0.01), cortisol (16.7 +/- 2.57 ng/dl----25.2 +/- 3.72 ng/dl; p less than 0.01) and DHEA (2.70 +/- 0.99 ng/ml----5.02 +/- 1.03 ng/ml; p less than 0.05) rose significantly. Generally, plasma insulin was not markedly influenced by isoflurane anaesthesia and surgery. No significant alterations in plasma catecholamine concentrations were observed.

Abdomen↗

[Contribution of the Saarland Cancer Register to the epidemiology of skin tumors].

2363 epitheliomas and 450 melanomas were reported to the Saarland Cancer Register between 1967 and 1978. We evaluated these 2813 cases and established the following ratio: Basal cell epithelioma: squamous cell carcinoma: melanoma = 63.4%:24%:12.5%: or 5:2:1. Bowen's disease, Bowen carcinoma and adenocarcinoma constitute a rarity. 80% of the basal cell epitheliomas, and 76% of the squamous cell carcinomas were localized on face, neck and head, the sites of predilection being the eyelids with basal cell epitheliomas, the lower lip with squamous cell carcinomas, and the ears with both epitheliomas in men. While no significant sex-related prevalence could be established for basal cell carcinoma, 56.5% of the squamous cell carcinoma were found in men, and 43.5% in women. The 450 melanoma-cases revealed a preference for women, the ratio of men:women turned out to be 1:1.58.

Adenocarcinoma↗

[Functional methods of esthetic facial surgery].

The subject "Funktionelle Methoden der Asthetischen Gesichtschirurgie' (Functional methods in facial aesthetic surgery) is described from the viewpoint of the otorhinologist. This surgical specialty is to care for the functions of 4 organs of sense, of the facial nerve, of ingestion, breathing and speaking. The accentuation in this publication lies on functional criteria. They are essential even in facial surgery with aesthetic motivations. 3 further papers refer to the surgical anatomy of the "isthmus pharyngis' and the problems of surgery of the velopharyngeal insufficiency and the nasopharyngeal atresia. The author describes his own surgical methods.

Face↗

[The surgery of nasopharyngeal stenosis (author's transl)].

The reconstructive surgery of the cicatricial velopharyngeal stenosis and atresia may often be difficult and it is sometimes impossible to cut viable flaps from the mucosa of the velum and/or pharynx or to bring free grafts to be taken. For permanent success of the surgery the covering of the lateral pharyngeal wall is essential. Our experiences on 5 operated cases are described as well as a personal surgical technique with flaps from the nasal mucosa.

Adolescent↗

[The anatomy of the Isthmus pharyngis (author's transl)].

The boundary between the nasal and oral part of the pharynx has not yet been named definitely in surgical anatomy. The term Isthmus pharyngis in analogy to Isthmus faucium is proposed and the anatomy of this region is described. The importance of these structures in reconstructive surgery is emphasized.

Humans↗

[The ethmoiditis of the child and the irrigation treatments by Proetz in short general anaesthesia (author's transl)].

From the anatomy of the sinuses in children and the follow-up of inflammatory diseases one can assume that in most cases the infection develops primarily in the ethmoid. We therefore believe that the diagnosis of chronic maxillary sinusitis in children is mostly wrong as well as the decision to operate upon the maxillary sinus before sanation of the ethmoid sinuses. The term pyosinus should be reintroduced to facilitate the differential diagnosis from sinusitis. Analogous to irrigation treatment of the maxillary sinus the displacement-method by Proetz is the only possible irrigation for the ethmoid sinus. The technique of Proetz-irrigation in short general anaesthesia is described and recommended. Prompt and effective treatment of ethmoiditis will avoid extension over the maxillary sinus. Thus surgery on the maxilla - very problematic in view of its growth - can be ommited in most of the cases.

Child↗

[Surgical treatment of lung abnormalities].

Four cases of lung malformations are presented. In this cases symptoms, diagnostic procedures, indications for operation and surgical treatment are discussed. Agenesis and aplasia of lungs do not require surgical treatment. Hypoplasia of the lung, an accessory lung and sequestrations leading to purulent-recurrent infections can be treated by resections.

Adolescent↗

[The collapse of the alae and inner valve of the nose (author's transl)].

The collapse of the alae and inner valve is caused more frequently be regressive changes of the aging tissues then by congenital weakness of the cartilaginous structures. Years ago we have published an operative method for the rehabilitation of this kind of nasal dysfunction. Now we have simplified our method and do not use any longer incisions in the vestibule of nose.

Aged↗