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Biomedical subjects

K Freudenthal

Publications and source records attributed to K Freudenthal.

9 recordsLinked to original sources
PubMed1983

[Scale formation in the AMDP (Society for Methodology and Documentation in Psychiatry) system].

The psychopathological and somatic symptoms documented by the AMDP-system on the admission of 1654 patients to the Psychiatric Clinics of the Universities in München und 659 patients in Berlin were factor analyzed. Eight factors could be extracted which describe the psychopathology on eight syndrome-scales. These factors could be cross-validated by factor analyses on random samples. In correspondence with the factors of the AMP-system the following syndromes were found: paranoid-hallucinatory, depressive, psycho-organic, manic, hostility, autonomic, apathy, obsessive-compulsive. For each of the 70 items which were associated with a factor we computed the percentage occurrence and item-scale-intercorrelations, for each of the eight syndrome-scales reliability-coefficients, intercorrelations and T-transformations. For further data-reduction second-order-factors were also computed.

Adult↗
PubMed1982

[A statistical comparison of the different factor analyses of the AMP-system (author's transl)].

The intercorrelations of five different factor-analytically derived syndrome solutions of the AMP-system were computed. The syndromes were based on the psychopathological symptoms of 2,269 patients on admission to the psychiatric clinic of the Free University of Berlin. The syndromes which were similar in content in the solutions of different clinics could be shown to intercorrelate quite highly. Only the different syndromes of stupor and obsession-compulsion did not show the same high degree of similarity. Between the syndromes of the solution of one clinic as well as between the solutions of different clinics high intercorrelations were computed comparing non-corresponding syndromes; this could be demonstrated for the syndromes of mania with hostility and of apathy with stupor and depression. For building syndromes in the AMDP-system in the near future the aim for independence of the syndromatic scales seems to be important.

Factor Analysis, Statistical↗
PubMed1981

[Building syndromes in the AMP-system (author's transl)].

The symptoms of 2269 psychiatric patients on admission, documented by the AMP (PAS) system, were factor-analysed to build syndromes of psychopathology. The nine syndromes could be cross-validated. We believe a useful description of the findings on admission can be made by the following syndromes: paranoid-hallucinatory, manic, psycho-organic, depressive, apathetic, hostile, stuporous, somatic, compulsive. The correlation with other syndromes based on AMP by other scientists is substantial. For each item we computed the percentage of occurrence and the item-scale correlation, and for the syndrome-scales reliability, intercorrelations and T-transformations. We calculated the mean profiles for some diagnostic groups to test some aspects of the validity of the syndromes. It was demonstrated that a differentiation is possible.

Adult↗
PubMed1981

[The potential of psychopathological symptoms to differentiate diagnostic groups (author's transl)].

We investigated the extent psychiatric illnesses can be differentiated by means of psychopathological symptoms. The present condition of 2269 patients was analyzed; they had been admitted to the psychiatric clinic of the Free University of Berlin during 1971-1976, as documented by the AMP (PAS) documentation system. The most frequent diagnosis in the sample was schizophrenia (32%), followed by neurosis (22%), affective psychosis (14%), addiction (6.7%), and organic psychosis (6.2%). We could demonstrate that even such diagnostic groups are usually discernible by symptoms, where the differential diagnosis is often difficult. Organic psychosis vs paranoid schizophrenia and depressive neurosis vs depressive psychosis can be determined, but manic syndromes in schizoaffective psychosis vs manic syndromes in affective psychosis are hardly discernible. The potential to differentiate, however, only pertains to diagnostic groups, since many individual patients cannot accurately be classified into diagnostic groups by psychopathological symptoms alone. Only a few symptoms are pathognomonic, and if there are pathogomonic symptoms characterizing a diagnostic group, only a few patients in this group show these symptoms. These results indicate, at least for the high number of patients without severe and typical symptomatology, that we must: 1. Achieve better differentiation on the diagnostic axis "psychopathology" by means of empirically derived syndromes instead of isolated symptoms. 2. Use other diagnostic axes (like etiology and course) for differential diagnostic purposes.

Adult↗
PubMed1977

AMP (PAS) and BPRS: a comparison of two assessment methods.

The aim of this investigation was to contribute to the validation of the AMP(PAS) system. As a criterion we used the BPRS because it has been accepted as one of the most widely used scales in the English-speaking countries. Our study includes the following steps: a) comparison of AMP syndromes and BPRS dimensions by computation of a factor analysis of both scales; b) comparison of each homogeneous group found by cluster analysis techniques of the AMP with its values on the BPRS: c) comparison of discriminative power of both scales concerning different groups (nosological or found by cluster analysis) by discriminant analysis. In a sample of 70 female patients with acute psychiatric symptoms we found that both scales describe psychopathological phenomena and classify patients in a very similar way. However, we were able to classify patients into homogenous groups by cluster-analysis techniques in a more consistent manner with AMP than with BPRS. Both scales gave better results in description and classification of psychoses than of neuroses, although the AMP system separates psychotic patients from neurotic patients more accurately than the BPRS. Our results suggest that the AMP system permits a more differentiated psychopathological description and a more accurate and consistent classification of psychiatric patients than the BPRS, at least in the special patient sample used for this investigation.

Adjustment Disorders↗
PubMed1975

[Practice and further development of the AMP-system (a report about a symposion and a seminar) (author's transl)].

During two days in November 1974 TV-tapes of psychiatric interviews were demonstrated and the psychopathology was documented on AMP-record sheet 3. It was a purpose of the discussion to get stimulation for the improvement of the AMP-manual and to decrease the interrater-variance. It was only the first tape which was not followed by a discussion. This film was presented a second time at the end of the seminar in order to examine the training effects. Both record-sheets were compared with each other. Generally the variance decreased. The discussion as to an improvement of the AMP-manual lead to the following suggestions: In defining a psychopathological item it is important to differentiate more precisely between the patient's subjective experience and his behaviour, to find better criteria concerning the rating of different intensities and to improve discrimination between singular items. Furthermore the logic of documentation procedure should be unequivocal and more practical. Following the seminar there was a symposion discussion more general and some specific methodological problems of the further development of the AMP-system. Finally study groups were formed to elaborate on the topics "AMP-manual", "rater-training", "social data" and "electronic data processing".

Berlin↗