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Biomedical subjects

K F Miller

Publications and source records attributed to K F Miller.

49 records · Page 3Linked to original sources
PubMed1980

Response of plasma LH and FSH to gonadotropin-releasing hormone in pony foals and ovariectomized pony mares.

Plasma FSH and LH response to a synthetic GnRH analog was measured in adult ovariectomized pony mares (OVX) and in pony foals (<70 days of age) during late spring (May-June). FSH and LH responded in a similar fashion (200% increase) in the OVX mare, which is different from other reports for intact mares. There was a greater mean response to a comparable dose of GnRH in the prepubertal foal for both FSH (500%) and LH (900%) than in the OVX mare. There was a positive correlation between age and the maximum FSH response to GnRH in male and female foals. The LH response was positively correlated with age in male foals, but not in females. The response to GnRH in the prepubertal foals was consistent with the previously observed patterns of gonadotropin secretion during this age period.

Journal Article↗
PubMed1979

FSH and LH concentrations in periparturient mares.

The influence of the ovaries and presence of a foal on periparturient concentrations of FSH and LH were studied in 19 Pony mares. In intact and ovariectomized mares, mean concentrations of FSH fluctuated between 1.1and 9.9 ng/ml on Days -14 to-1 before parturition (Day 0). A surge of FSH occurred in all mares in association with parturition. From Days 1 to 10, the high levels of FSH gradually decreased in the intact group to the minimal concentrations that occur during oestrus, but remained elevated in the ovariectomized mares. There were no significant pre-partum changes in LH in either type of mare. Post-partum changes in LH concentrations increased at a similar rate in ovariectomized and intact mares. The presence of a foal significantly lengthened the interval to first oestrus, depressed LH levels on Days 6--10 and decreased the FSH concentrations as averaged over the 10 days before the first ovulation after parturition.

Animals↗
PubMed1979

Follicular and gonadotrophic changes during transition from ovulatory to anovulatory seasons.

Observations of follicular and gonadotrophic changes were conducted on 14 Pony mares for 31-day periods beginning at the penultimate (second last) ovulation and at the last ovulation of the season. There were no main effects or interaction of day or period on the numbers of small follicles (less than 20 mm). Concentrations of FSH, numbers of large follicles (greater than 20 mm), and oestrous behaviour each showed an effect of day (P less than 0.01), but no effect of period. Concentrations of LH and diameter of the largest follicle each showed an interaction (P less than 0.01) between day and period attributable primarily to smaller values on Days 18--24 after the last ovulation than after the penultimate ovulation. It was concluded that, of the factors considered, failure of ovulation at the onset of the anovulatory season was due to lack of an adequate ovulatory LH surge and final growth of a preovulatory follicle.

Animals↗
PubMed1978

Blood pressure control: the effect of facilitated access to treatment.

1. Effectiveness of hypertension care has been compared in patients treated at a Union health centre and at their place of work. 2. Patient adherence and blood pressure control is not affected by the place of treatment. 3. A systematic approach to treatment can be successful in a large population group.

Follow-Up Studies↗
PubMedDate not supplied

The effect of follicular fluid reactive oxygen species on the outcome of in vitro fertilization.

OBJECTIVE: To examine the presence of reactive oxygen species (ROS) in the follicular fluid of women undergoing in vitro fertilization (IVF) and identify its role in pregnancy outcome. STUDY DESIGN: In this prospective study, ROS and total antioxidant capacity (TAC) levels were measured by the chemiluminescence method in the follicular fluid of 53 women. Age, number of oocytes recovered, percentage of oocytes fertilized, ROS and TAC levels were compared in women who did and did not become pregnant. RESULTS: Patients who become pregnant had significantly higher log-transformed ROS levels (1.01 +/- 0.14, P = 0.031 than those who did not (0.69 +/- 0.08). Women with endometriosis or male factor infertility who became pregnant had significantly higher ROS levels (1.44 +/- 0.23 and 1.31 +/- 0.19) than those who did not (0.60 +/- 0.17 and 0.67 +/- 0.16; P < .006 and P < .01). CONCLUSION: Follicular fluid ROS, at low concentrations, may be a potential marker for predicting success in IVF patients.

Age Factors↗
PubMedDate not supplied

Vaccination with F-strain Mycoplasma gallisepticum to reduce production losses in layer chickens.

The effect of Mycoplasma gallisepticum (MG) infection or vaccination of Conn. F-strain MG on 45 weeks of egg production was analyzed using production records from 132 flocks of commercial layer hens. The flocks were located in Pennsylvania, and the data were collected for two years. On the average, layers maintained free from infection with MG laid 15.7 more eggs/hen housed than the MG-infected layers; figures were adjusted for layer-strain effect. This adjusted advantage decreased to 8.7 eggs/hen housed when uninfected flocks were compared with vaccinated flocks. Adjusted average production of vaccinated flocks was 7.0 eggs/hens housed more than production of MG-infected flocks. Egg production of four layer strains was observed with respect to vaccination or natural infection with MG. The four strains responded similarly whether vaccinated or infected. Route of vaccination and age of layer at time of vaccination influenced egg production of vaccinated birds. The adjusted average production/hen housed was 4.9 eggs greater for birds vaccinated via drinking water than for birds vaccinated via spray. The adjusted average was 10.3 eggs/hen housed greater for birds vaccinated between 8 and 18 weeks of age than for birds vaccinated after 18 weeks.

Animals↗