Biomedical subjects

K F Koh

Publications and source records attributed to K F Koh.

20 records · Page 2Linked to original sources

PubMed1994

Septic shock in a surgical intensive care--validation of multiorgan and APACHE II scores in predicting outcome.

We analysed retrospectively the records of 353 admissions to the National University Hospital's Surgical Intensive Care Unit over a one-year period and found 25 patients with septicaemic shock requiring vasoactive therapy. The mortality rate was 68%. Blood cultures were positive in only 36%. We validated the ability of the Acute Organ System Failure score, Multiorgan Failure score, Organ System Failure score and Acute Physiology and Chronic Health Evaluation II (APACHE II) score to predict outcome at onset of septic shock. Only the APACHE II was a significant predictor of outcome, the rest having poor predictive ability. We conclude that the present scoring systems are too inaccurate for us to base important clinical decisions on.

APACHE↗

PubMed1993

Validation of APACHE II score in a surgical intensive care unit.

The APACHE II scoring system was applied to 301 surgical intensive care admissions over a 9-month period. The mean age of patients admitted was 52.39 years (SD 19.3) and the mean duration of stay was 5.37 days (SD 8.93). The overall mortality was 17.27%. The mean APACHE II scores for survivors was 12.94 (SD 7.43) and non-survivors 28.19 (SD 10.43). There was good correlation between expected mortality predicted by the APACHE II system and observed mortality (r = 0.9732). Using a predicted risk criterion of 0.5 to distinguish between those predicted to survive and die, of the 45 patients predicted to die, only 30 actually did so. No patient survived with an APACHE II score of more than 40 and with a predicted risk of death greater than 0.87. We found the APACHE II system useful for evaluating ICU performance and risk stratification for the purpose of therapeutic trials but not as a triage tool.

Adolescent↗