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Biomedical subjects

K Engelhard

Publications and source records attributed to K Engelhard.

29 records · Page 2Linked to original sources

[The use of new turbo spin-echo pulse sequences with and without fat suppression in the diagnosis and staging of prostatic carcinoma].

MR studies using turbo spin-echo pulse sequences (TSE) were performed on 27 patients with histologically confirmed prostate cancer. A prospective study was conducted in 15 patients who underwent radical prostatectomy. Turbo SE pulse sequences generate strongly T2-weighted images of excellent quality with reduction of measurement time by a factor of 4-6. A comparison with standard T2-weighted spin-echo pulse sequences indicated an objective improvement in the contrast of pathological structures (p < 0.001). With respect to differentiation of stages T2 and T3 (TNM) during pathohistological correlation, sensitivity of 80%, specificity of 40% and an accuracy rate of 67% were obtained. Sensitivity of 71% and specificity of 75% were obtained when decoding cases of infiltration into the seminal vesicles, with an accuracy rate of 73%.

Adipose Tissue↗

Ultrasonic examination of the wall of the fluid-filled stomach.

The ultrasonographic examination of the fluid-filled stomach in five standardized positions permits the transabdominal visualization of the gastric wall in all sections of the organ. In a prospective study, 107 patients were examined--68 with a pathological change in the wall of the stomach and 39 with no gastric disease. In 56 patients (82.4%) the lesion was correctly identified. In addition to wall-infiltrating processes and stenoses, circumscribed space-occupying lesions were also detected; for example, localized carcinomas, leiomyosarcomas, lymphomas, leiomyomas, polyps, giant folds, and impressions of the gastric wall. Thirty-seven patients (94.9%) with no gastric disease were considered normal at the ultrasonographic examination. The procedure suggests itself not only as a supplement to endoscopy and diagnostic X-rays, but also as a diagnostic alternative in selected patients who cannot be stressed by these methods. The exclusion of gastric disease by this technique is not possible.

Beverages↗

[Renal space-occupying lesion of uncertain tumor status in metastatic testicular tumor].

On the basis of a particular case of "atypical" hypernephroma the main differential diagnosis of solid renal masses are described with reference to the basis disease: testicle tumour causing metastasis. The problems of determining the dignity of the disease by methods of sonography, pyelogram and CT are pointed out as well as the differences between those characteristics of the said tumour revealed by x-ray diagnosis and the known characteristics of substantial kidney deformations as described in medical literature.

Adult↗

[Mesotheliomas of the pleura and peritoneum].

From 1972 and 1982 we observed 6 cases of diffuse pleural mesothelioma and 3 cases of peritoneal mesothelioma in the Department of Internal Medicine of the University of Erlangen-Nürnberg. In 5 of 6 cases one sided noncharacteristic relapsing pleural effusion was the only sign of the pleural tumor process. Only in one case a pleural tumor constallation was diagnosed. Tomography of the lung showed a normal free central bronchial system and peripheral bronchial infiltration or displacement. In all cases CT scans were able to localize the tumor furthermore to demonstrate the exact extension and the infiltration of the mediastinum or of the diaphragm into the abdomen. Beside conventional x-rays such as double contrast examination of the colon and mesenterial angiography CT scans played the major role in diagnosing this rare peritoneal mesothelioma. Massive ascites, mesenterial infiltration, thickening of the mesenterial radix, and tumor embedding of bowel and vessels is of diagnostic significance. To ensure the diagnosis one has to do a thoraco- or laparoscopy.

Bronchography↗

[Pancreaticorrhagia--imaging procedures compared].

Four patients with spontaneous bleeding from the pancreas are described. Transpapillary bleeding is diagnosed endoscopically. Angiography can demonstrate the eroded vessel directly. Ultrasound, CT and ERCP demonstrate the underlying abnormality in the pancreas. Bleeding into a cyst produces characteristic echoes, or an increase in density. NMR is able to demonstrate pancreatitis and pancreatic pseudo-cysts. Early diagnosis is extremely important, since without appropriate surgery, pancreatic bleeding is frequently fatal.

Adult↗