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Biomedical subjects

K E Richard

Publications and source records attributed to K E Richard.

32 records · Page 2Linked to original sources

[Clinical and prognostic aspects of congenital hydrocephalus].

Clinical data of 24 patients with congenital hydrocephalus are presented. 13 children died within the first 7 months of life; the average period of survival was 2 months. Associated malformations of the CNS or other organs, severely raised intracranial pressure in utero, and postnatal complications involving the CNS indicated a poor prognosis. The follow-up of the 11 surviving children showed severe neurologic sequelae and drug resistent epilepsy in 2 of them. Three others had neural tube defects and associated paraplegia. The 6 remaining children had mild or moderate cerebral palsy or were moderately mentally retarded. If possible, birth should not be induced before 36 weeks of gestation, and the hydrocephalus should be shunted soon after birth. Satisfactory results can be obtained in about one half of surviving patients by early shunting of congenital hydrocephalus.

Brain Damage, Chronic↗

[Criteria of brain death: 3d generation. Interpretation of criteria established by the Federal Chamber of Physicians in determining brain death].

The criteria of brain death published by the Federal Chamber of Physicians in 1982 in their second generation have stood the test of time and remain valid. The most important amendments in issuing a third generation are the following: In primary cerebral lesions supratentorial lesions have to be distinguished from infratentorial processes. In primarily the infratentorial processes EEG activities of the cortex max outlast apneic brain stem areflexia. Therefore in infratentorial processes controls of the EEG are indispensable. The extinction of evoked potentials, certain conditions being observed, may prove the loss of brain stem function and therefore may allow to shorten observation time, and may offer an alternative to isoelectricity in the EEG or cerebral perfusion stop as a diagnostic procedure. Additional tests for brain death are commented on. Special considerations are necessary in brain death in children.

Brain Damage, Chronic↗

[Ventricular fluid pressure measurement by microcatheter and pressure-controlled external fluid drainage (author's transl)].

Long term control of ventricular fluid pressure by means of a ventricular catheter offers the advantage of pressure-controlled external fluid drainage, especially in patients with space-occupying processes which lead to acute disturbances of the fluid circulation. In a measuring system with the possibility of drainage it is advisable to measure the VFP with a microcatheter. The microcatheter is introduced through the drainage catheter. Both catheters are placed in the anterior part of a lateral ventricle. Communication between the drainage system and the transducer is avoided. There is no necessity for frequent disinfection or changing of parts of the system during long term control of the patient. Any occlusion of the drainage system can be recognized immediately because the measuring procedure will not be interrupted by such an occlusion. In 201 patients the ventricular fluid pressure was recorded by the microcatheter method for a total of 1086 days. The infection rate was under 1%. With simultaneous external fluid drainage it rose to 2.2%. For patients with space--occupying processes of the posterior cranial fossa external drainage is recommended for 5--10 days postoperatively as a precaution against rises in CSF pressure.

Catheterization↗

Primary myeloblastoma of the pineal region.

The first case of a pinealis region tumor of the hematopoietic system without known leukemia (so-called primary myeloblastoma, primary granulocytic sarcoma) is reported. Two weeks after resection, the 3.5-year-old patient suffered from a local recurrence. At this time, a bone marrow infiltration by leukemic blasts was diagnosed for the first time. An aggressive chemotherapy and radiation induced a complete remission, over a 26-month follow-up period. We examined the removed tumor tissue by routine histology methods, immuno- and enzyme histochemistry and electron microscopy. The CSF was studied by conventional microscopy and enzyme cytochemistry. We discuss the epidemiological data of nine previously published cases of primary intracranial myeloblastoma.

Brain Neoplasms↗