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Biomedical subjects

K E Moore

Publications and source records attributed to K E Moore.

At least 271 records · Page 15Linked to original sources

Dopamine: release from the brain in vivo by amantadine.

After dopamine stores in the caudate nucleus of cats were labeled with [(3)H]dopamine, the ventricular system was perfused with artificial cerebrospinal fluid. The addition of amantadine to the perfusing fluid caused a doserelated increase in the concentrations of [(3)H]dopamine appearing in the perfusion effluent. Subthreshold concentrations of amantadine also enhanced the efflux of [(3)H]dopamine induced by electrical stimulation of the caudate nucleus.

Amantadine↗