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Biomedical subjects

K Duncan

Publications and source records attributed to K Duncan.

84 records · Page 5Linked to original sources
PubMed1979

Death during jogging or running. A study of 18 cases.

We investigated the circumstances of death and the medical and activity histories of 18 individuals who died during or immediately after jogging. Thirteen men died of coronary heart disease (CHD) and four men and one woman died of other causes. Six CHD subjects had medical histories relevant to the cardiovascular system, but only one had diagnosed CHD. Six CHD subjects experienced prodromal symptoms but continued vigorous exercise programs. Two subjects had exercised less than a month, but most had trained regularly for years. The CHD risk factors for the CHD cases did not differ significantly from those for other age-matched, physically active men. Superior physical fitness does not guarantee protection against exercise deaths. Physicians and exercising adults should be aware of this fact and give appropriate attention to possible prodromal symptoms.

Adult↗
PubMed1976

Plugged in.

Explore the source record for details and available documents.

Occupational Health Services↗
PubMedDate not supplied

Creating clinical opportunities in a managed care environment.

The Continuum of Care clinical experience was developed to provide future nurses with practice in a managed care environment. Students see how the critical care patient's needs change during the recovery process and assist the patient with the transition to self-care at home. Patient and student evaluations indicate the experience increases students' understanding of the role of the nurse in managed care while facilitating patients' transition to the self-care environment.

Clinical Competence↗
PubMedDate not supplied

Student pre-entry experience and first year of employment.

BACKGROUND: Student clinical and work-related experiences are available at many healthcare organizations, but little is known about how these experiences contribute to the employer/nurse work relationship that begins after graduation. This study examined the relationship of senior BSN students' past employer experience in describing first-year employer commitment and turnover. METHODS: The sample was 63 senior BSN students. Experience factors measured included job selection factors, pre- and one-year commitment, organizational climate, employer support, and first-year turnover. RESULTS: Organizational climate was the experience-related factor most important in explaining first-year commitment. CONCLUSION: Findings suggest the importance of supportive work environments to new nurses both before and after accepting the first graduate nurse position.

Adult↗
PubMedDate not supplied

Effects of individual performance feedback on nurses' adherence to pain management clinical guidelines.

The purpose of this study was to examine the effects of an individual performance feedback intervention on nurses' adherence to pain management practice guidelines. Thirty orthopedic staff nurses received individual performance feedback on their past performance of three recommended pain management practices. Nurses' performance of the three recommended practices significantly improved over the 15 weeks after the feedback intervention. Missed 4-hour pain assessments declined (t = 8.77, df = 239, P < 0.0001), reassessments after analgesics increased (t = -5.71, df = 239, P < 0.0001), and follow-up taken for unacceptable pain increased (t = -3.08, df = 178, P < 0.01). Results suggest that individual performance feedback may be an effective approach to improving nurses' pain management intervention activities.

Arthroplasty, Replacement, Knee↗
PubMedDate not supplied

The molecular biology of human renin and its gene.

The molecular biology of renin, prorenin, and the renin gene have been studied. A tissue-specific pattern of expression was found in rat and human tissues. In the human placenta, the transfected and endogenous renin promoters are active, and renin mRNA levels and transfected promoter activity are increased by a calcium ionophore plus cAMP. Cultured pituitary AtT-20 cells transfected with a preprorenin expression vector mimick renal renin release by converting prorenin to renin and releasing renin in response to 8Br-cAMP. Studies with mutant renin genes suggest that the body of renin directs renin to the regulated secretory pathway, and renin glycosylation affects its trafficking. Chinese hamster ovary cells were used to produce recombinant prorenin. Infused prorenin was not converted to renin in monkeys. Renin crystals were used to determine its three-dimensional structure. Renin resembles other aspartyl proteases in the active site and core, but it differs in other regions that probably explain renin's unique substrate specificity. Based on structural and mutational analysis, a model for human prorenin was built that suggests lysine -2 of the prosegment interacts with active site aspartate residues, and that the prosegment inactivation of renin is stabilized by binding of an amino terminal beta strand into a groove on renin.

Animals↗
PubMedDate not supplied

Making HIV prevention work in the north.

Meeting the challenges of diverse cultures, numerous languages and great distances, the Northwest Territories discovered innovative ways to promote AIDS prevention. This article discusses obstacles to HIV prevention and techniques used to overcome them commonly found in health services for the NWT. For example, techniques for improved service delivery include reliance on decentralized services provided by regional health boards and Community Health Representatives. Further, the challenges posed by language diversity and cultural taboos against speaking openly about sexual matters have been partially overcome through the conversion of materials and concepts into aboriginal languages which are culturally appropriate. The article specifically discusses two AIDS education campaigns in which these techniques were utilized: namely, Health is a Community Affair Campaign (or the Door-to-Door Project) and local initiatives which hosted presentations by an Aboriginal person living with AIDS.

Adolescent↗