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K D Schmidt

Publications and source records attributed to K D Schmidt.

7 recordsLinked to original sources

Thermoregulation and fever in normal persons and in those with spinal cord injuries.

Thermoregulation and fever are primarily mediated through the hypothalamus and its effector mechanisms. In persons with complete spinal cord injuries above T-6, thermoregulation is substantially impaired because of the interruption of neuronal pathways to and from the hypothalamus. These same pathways are important in the production of fever in response to infections, and injury to these pathways in patients with high-level spinal cord injuries should diminish their ability to mount a febrile response. In clinical practice, however, measurements of body temperature are used to make decisions in patients with spinal cord injuries in a manner similar to that in patients without spinal cord injuries. In this article, we review the literature on thermoregulation and fever in normal persons and in those with complete spinal cord injuries and propose possible mechanisms for fever in persons with high-level spinal cord injuries.

Body Temperature

[Differential choice of the procedure in the surgical treatment of fractures in the trochanteric area].

718 trochanteric fractures, surgically treated with nailing according to Ender, 130 degrees angled blades of AO, 95 degrees condyle blades of AO, valgisation blades of AO and the (DHS) dynamic hip screw of AO were followed up for anatomical reconstruction, early weight-bearing, complications and spectrum of indication. The best surgical method is the DHS-osteosynthesis, easy to perform, weight-bearing at once, low rate of complications and good results by a broad spectrum of indications. Subtrochanteric fractures should be treated with 95 degrees condyle blade and unstable fractures connected with destruction of Adam's bow with valigisation osteotomy and valgisation blade.

Bone Nails

[Case studies of the effect of tyrosine administration in children with phenylketonuria on cognitive processes].

Eight patients with phenylketonuria and low protein nutrition were treated in a double blind crossover study for the time of 3 month with 150 mg tyrosine per kg body weight and day and placebo thereafter or vice versa. The concentration of phenylalanine in serum was not influenced by the administration of tyrosine whereas tyrosine in serum markedly increased. Psychological tests were 7 times repeated in monthly intervals. From the study it is to suggest that there is an improvement of the test results caused by an effect of training due to the repeated tests and an additional improvement caused by tyrosine.

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