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Biomedical subjects

K D Salbiev

Publications and source records attributed to K D Salbiev.

6 recordsLinked to original sources
PubMed1995

[The tissue basophils of the rat mesentery under the influence of a permanent magnetic field].

Effect of constant magnetic fields (CMF) of low energies (B = 35 mT, E = 350 Oe) on the system of mesenterial mast cells (MT) was studied by methods of light and electron microscopy in 140 outbred albino rats of both sexes for 1 day. The results obtained indicate active reaction of mesenterial MC on the CMF effect. Their activity is cyclical. High lability of the cellular system was demonstrated. Sexual peculiarities of the reactivity on different stages of CMF action also exist. Mesenterial MC reaction forms the complex of reactions of nonspecific adaptation to light irritants. Mesenterial MC response occurs stagely: orientation, training and relative training. The latter provides change of the tissue homeostasis on a qualitatively new level. Increase of passive and active resistance occurs simultaneously in training phase. This confirms the possibility of use of the CMF of low energies in complex of therapeutic treatment.

Animals↗
PubMed1977

[Clinical and morphological correlational analysis of different forms of myocardial infarct].

On the basis of a mathematical analysis carried out by a "Minsk--220" computer, the correlation between the most essential morphological changes in the coronary arteries, the peculiarities of myocardial infarction, history and its clinical manifestations were studied in 320 myocardial infarction cases (148 males and 172 females over 50 years of age) with the distinction of 276 clinical and morphological signs. The numerical assessment of the conjugation indices of the morphological changes and the clinical-laboratory data permitted to evaluate the role of each of the examined factors in the genesis of primary and secondary myocardial infarctions, their spreading in the heart muscle, and their clinical manifestations. It has been demostrated that similar changes in the coronary arteries that create a background for a relative circulatory insufficiency are realized in different forms of myocardial infarction. Relative coronary insufficiency varies widely and becomes the leading cause of myocardial ischaemia. The effect of other factors is interpreted as modifying, and some of them--as triggering. The presented correlations analysis proves the rationale of assessing each case of myocardial infarction in terms of the probability theory of patho- and morphogenesis of ischaemic heart disease.

Aged↗
PubMed1976

[Microspectrophotometric study of oxidative enzyme activity in experimental myocardial ischemia].

The method of comparitive microspectrophotometry was used to study the changes in the activity of oxidative enzymes in the zone of ischaemia and the juxtaischaemic region of the cardiac muscle in rabbit experiments (104 animals, including 10 controls). A certain periodicity was noted in the changes of the activity of oxidative enzymes in separate zones of the ischaemic myocardium during different periods of the infarction development and healing. The terms of maximum reduction of the enzymatic activity falling within the 4th-6th and 24th hours and 2nd day should be taken into account while developing the methods of metabolic protection and enzyme therapy of the ischaemic myocardium.

Animals↗
PubMed1976

[Microspectrophotometric study of DNA concentration in the nuclei of muscle cells in the peri-infarct zone of the rabbit heart].

A comparative microspectrophotometric study of the nuclear DNA content in the myocardial cells of the periinfarction region of the left ventricle was made in rabbit hearts during different periods of experimental ischemia. A moderate increase of both the polyploid and amitotically divided nuclei were revealed. This results are discussed from the aspect of possible participation of nuclear polyploidia and mitotic division in the mechanisms of intracellular regeneration of the myocardium.

Animals↗