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Biomedical subjects

K D Nielsen

Publications and source records attributed to K D Nielsen.

6 recordsLinked to original sources

A simple format for exchange of digitized polygraphic recordings.

A simple digital format supporting the technical aspects of exchange and storage of polygraphic signals has been specified. Implementation of the format is simple and independent of hard- or software environments. It allows for any local montages, transducers, prefiltering, sampling frequencies, etc. At present, 7 laboratories in various countries have used the format for exchanging sleep-wake recordings. These exchanges have made it possible to create a common database of sleep records, to compare the analysis algorithms local to the various laboratories to each other by applying these algorithms to identical signals, and to set up a computer-aided interlaboratory evaluation of manual and automatic analysis methods.

Algorithms

Zopiclone in the treatment of sleep abnormalities in fibromyalgia.

The clinical and polysomnographical effects of zopiclone were evaluated in 41 patients with fibromyalgia in a double blind controlled study. A significant improvement was observed regarding tiredness during the day and subjective sleep complaints, but no effects on pain or stiffness were observed. The sleep structure remained unchanged during treatment. Zopiclone seems to be of value in treating the sleep complaints in patients with fibromyalgia.

Aged

Laryngospasm-induced pulmonary oedema.

A case of pulmonary oedema following laryngospasm in a healthy young woman is reported. Laryngospasm occurred following surgery and was treated with positive pressure oxygen ventilation by mask and by deepening of the level of anaesthesia. The rest of anaesthesia was uneventful. During the following hour, spontaneous respiration deteriorated progressively and ended in manifest pulmonary oedema which was treated by endotracheal intubation and mechanical ventilation with PEEP for some hours.

Adult