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Biomedical subjects

K Chalmers

Publications and source records attributed to K Chalmers.

At least 37 records · Page 2Linked to original sources

Lifestyle counselling: the need for diagnostic clarity.

Three approaches to changing lifestyle behaviours are hypothesized. The argument that diagnostic accuracy is essential for selection of appropriate nursing interventions is developed and illustrated with clinical examples. The diagnoses of information deficiency, information and behavioural control deficiency, and contextual awareness deficiency guide the interventions for the problem of obesity.

Adult↗

Serum pepsinogen levels and Ostertagia ostertagi populations in clinically normal adult beef cattle.

Serum pepsinogen levels and Ostertagia ostertagi populations in clinically normal grass-fed bullocks were investigated in three groups of 10 prime cattle aged between 2.5 and 2.75 years slaughtered in late summer (February), early autumn (March) and late autumn (May) respectively. Apart from occasional foci of mucosal hyperplasia abomasa were grossly normal. Serum pepsinogen levels ranged between 0.2 and 2.5 i.u./l with group means of 1.4, l.5 and 1.3 i.u./l. O. ostertagi counts ranged between 0 and 5,194 with group means of 734,630 and 701 worms. The composition of the worm populations varied with a higher proportion of adults recovered in February and very few worms from most cattle in March, suggesting the termination of a parasite generation. An increase in numbers of early fourth-stage larvae in May indicated exposure to a new generation. These changes were not reflected in the pepsinogen levels. The findings are discussed in relation to the adequacy of the pepsinogen assay as a diagnostic aid in field infections, animal age, and correlations between pepsinogen levels and parasite populations.

Journal Article↗

Isolation and characterization of a lambdapolA transducing phage.

A plaque-forming lambdapolA phage was isolated from a population of transducing phage made in vitro from Escherichia coli DNA and a phage vector digested with restriction endonuclease HindIII. Amber mutations, in genes whose products are necessary for late protein synthesis (Q) and cell lysis (S), were crossed into the lambdapolA phage. Infection of either polA+ or polA- bacteria with this phage, under conditions permitting DNA replication but preventing phage production and lysis, elevated the levels of DNA polymerase I to between 75- and 100-fold that detected in a wild-type strain. The kinetics of enzyme production suggest that the polA gene is transcribed from its own promoter rather than from any of the well-characterized phage promoters. The fragment of E. coli DNA within the lambdapolA phage comprises approximately 5000 base pairs, sufficient to accommodate the polA gene and one, or two, coding sequences for smaller proteins.

Coliphages↗

Rural families' perspectives on having a child with cancer.

The goal of this study was to explore and describe the experience of being or having a child with cancer in a rural geographic area. An exploratory, descriptive study was conducted that used semistructured, in-depth, tape-recorded interviews as the primary data collection method. Ten rural families who each had a child with cancer formed the sample. Data were analyzed with qualitative analysis procedures. Families' descriptions revealed that their experiences were fraught with challenges that were due to living a great distance from the cancer treatment center. Descriptions of their experiences are presented in this report. Recommendations for health care professionals, particularly pediatric oncology nurses, to assist rural families in coping with their challenges are also offered.

Adolescent↗

Questioning: an intervention for health promotion.

In the health professions, questioning is traditionally viewed as a way of gathering information from a client as well as a way of developing the affective domain or how the client feels. The development of the cognitive domain, or how the client thinks, receives less attention. This article describes a clinical nursing approach using Bloom's Taxonomy to question clients' thinking behavior. Examples from nurses' files are used to clarify this approach.

Behavior Therapy↗