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Biomedical subjects

K C Lun

Publications and source records attributed to K C Lun.

78 records · Page 5Linked to original sources

Plasma estradiol as a predictor of preterm labor.

Studies have shown a rapid rise of plasma estradiol-17beta in the maternal circulation before the occurrence of preterm labor. We have attempted to perform a linear regression analysis of the data from normal pregnancies and to set up a 95% upper prediction limit for the normal range of the estradiol level for each week of gestation. The prediction limits were reasonably good, with only five (13%) false negatives. False negatives tend to occur only in late pregnancy.

Estradiol↗

Analysis of cost-effectiveness of different strategies for hepatocellular carcinoma screening in hepatitis B virus carriers.

A mathematical model was used to calculate the efficacy of screening to detect hepatocellular carcinoma at a resectable stage in hepatitis B virus carriers. Data relating to tumour incidence, efficacy of screening tests and tumour growth times were obtained from a literature review. Various tests were costed according to charges currently prevailing at the authors' institution. The cost per early tumour detected is inversely proportional to tumour incidence. It is relatively low for populations with high incidences of hepatocellular carcinoma for example, male carriers over the age of 30. Both the costs and the proportions of early tumour detected increase with increasing frequency of screening. However, the use of ultrasonography at 10 monthly intervals or both ultrasonography and alpha-fetoprotein estimation at yearly intervals will detect 90% of tumours early at a cost of S$20,000 (US$11,800) per early tumour detected. The results would be significantly altered if tumour growth times were markedly different from those reported in the literature.

Australia↗

The role of Chinese traditional medical practice as a form of health care in Singapore. I. Preliminary study.

A retrospective study of 672 sampled records of patients of a major institution providing Chinese traditional medicine in Singapore reveals that 97.3% of the patients were Chinese, with a dialect group distribution following closely that of the Singapore Chinese. The male-to-female patient ratio was 1.0:1.13. There were fewer patients of the pediatric age group and more of those from age 30 upwards. Some 43% of the patients sought treatment for "infective" and "internal, emotional and weakness" diseases. The prevalent disease conditions seen among patients from the different age groups are also analyzed and discussed in this paper.

Adolescent↗

Application of the microcomputer to the estimation of adult survivorship by indirect techniques.

This paper, the second in a series on the application of the microcomputer to the estimation of vital rates by indirect techniques, deals with the measurement of adult survivorship. Two of the most widely used techniques for the estimation of adult survivorship using indirect techniques are the Widowhood method and the Orphanhood method. A review of the Widowhood method, developed by Hill and Trussell, is given followed by a detailed description of the use of the computer program for the conditional regression variant of the method using data on age of respondents (widowed males or females). A full listing of the program, written in TRS-80 BASIC, is available on request. The program for the Orphanhood method will be given in a paper to follow.

Adult↗