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Biomedical subjects

K C Lim

Publications and source records attributed to K C Lim.

At least 55 records · Page 3Linked to original sources
PubMed1986

Some problems encountered in endodontic radiography.

This retrospective survey highlights some of the problems faced by undergraduate students using the bisecting angle technique in endodontic radiography. The radiographs of maxillary incisors and premolars were observed to suffer from a greater amount of distortion than radiographs of the corresponding mandibular teeth. Further, the presence of rubber dam equipment affected the accuracy of the radiographs, and this was more apparent on the radiographs of the maxillary incisors and premolars compared to the mandibular incisors and premolars. Other problems identified included superimposition, indistinct and missed root apices. Methods to overcome these problems are suggested.

Bicuspid↗
PubMed1982

A study on the prevalence of antibodies to Toxoplasma gondii in Singapore.

The indirect fluorescence antibody technique has been employed to study the prevalence of toxoplasma antibodies in Singapore. 42.5% of clinically suspected cases of toxoplasmosis showed antibody titres. Of these, 17.5% had titres greater than or equal to 1.64. Malays and Indians have higher positive rates compared to the main ethnic group, the Chinese. Antibody titres are found in both males and females and span through the various age groups. The possible mode of transmission is discussed and the importance of congenital toxoplasmosis is indicated.

Adolescent↗
PubMed1980

Zoonotic implications of cats and dogs in filarial transmission in Peninsular Malaysia.

Filarial infections in 447 cats and 68 dogs from six endemic areas of human filariasis in Peninsular Malaysia were studied as part of the study on the zoonotic transmission of subperiodic Brugia malayi infection. 20.6% of cats and 57.4% of dogs had filarial infections. Cats were infected with subperiodic B. malayi, B. pahangi, Dirofilaria repens and D. immitis. Dogs were infected with B. pahangi and D. immitis. 6.9% of the cats had subperiodic B. malayi infection. The zoonotic implications of these infections and their impact on the filariasis control programme in Peninsular Malaysia were discussed.

Animals↗
PubMed1977

Experimental Brugia malayi infections in the rhesus monkey.

Twenty-eight rhesus monkeys in 3 groups were exposed to single (Group I), double (Group II), and multiple (Group III) inoculations with B. malayi infective larvae. Infections were monitored by microfilarial and blood counts, selected biochemical tests, IFA responses, and records of body temperature and lymphadenopathy before and/or after treatment with DEC. As a whole, the highest microfilaraemia levels were observed in Group II and lowest in Group III monkeys. Eosinophilia was a common occurrence but reached the highest mean levels in Group III. Intermittent fevers and lymph node enlargements were observed in all groups of monkeys and the occurrence of these appeared to be correlated. No definite pattern of antibody production was discernable among groups, but an inverse relationship existed between microfilaraemia and detectable microfilarial antibodies. Treatment with DEC produced a microfilaraemia-taxic effect within the initial half hour and responses to treatment varied according to individuals. Although post-treatment reinfection appeared to cause lymphoid responses and tissue eosinophilia, no substantial resistance to reinfection was observed.

Aedes↗
PubMed1976

Experimental dirofilariasis in macaques. III. Susceptibility and host responses to Dirofilaria tenuis of raccoons.

In this third of a series of studies on experimental dirofilariasis in primate hosts, 3 Macaca cynomolgus, 6 M. speciosa, and 2 M. mulatta were inoculated with infective larvae of Dirofilaria tenuis, a parasite of the raccoon, and were killed at periods ranging from 2 weeks to 13 months of infection. One M. mulatta and one M. speciosa were treated daily with prednisolone beginning 2 months after inoculation; worms were recovered from these and 5 other monkeys (7 of 11). Microfilaremia was detected during the 28th week of infection in a monkey under prednisolone treatment. Microfilaremia was found to be aperiodic in that monkey and in a raccoon. Eosinophilia and antibodies to the microfilaria reached appreciable levels in three monkeys harboring gravid worms. Development of D. tenuis in M. speciosa appeared to be comparable to that observed in man.

Animals↗
PubMedDate not supplied

Schistosoma mansoni: sex-specific modulation of parasite growth by host immune signals.

Development of female schistosomes from infectious cercariae to mature egg-producing adults requires both male schistosomes and an intact adaptive immune system. By examining single sex infections in immunodeficient mice, we provide evidence that female schistosome development is not directly influenced by the adaptive immune system, whereas male development is. Our data are consistent with a sequential model of schistosome development, where the adaptive immune system signals development of mature males, which subsequently stimulate development of mature females. The male schistosome therefore appears to play a central role both in transducing signals from the adaptive immune system and in facilitating female development.

Animals↗