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Biomedical subjects

K C Francis

Publications and source records attributed to K C Francis.

10 recordsLinked to original sources

Major vascular reconstruction for limb salvage in patients with soft tissue and skeletal sarcomas of the extremities.

Thirteen patients with sarcomas of the extremities have been treated with radical en bloc resection requiring vascular reconstruction as initial treatment. In one instance, vascular reconstruction failed. Eight patients are currently alive and free of disease. There were two instances of a local recurrence. Each of the remaining five patients who died had distant metastases develop, none of whom had a local recurrence. Vascular reconstruction with prosthetic bone replacement, when indicated, offers an alternative approach to the treatment of tumors which, because of attachment to major vascular structures, might be considered for radical amputation.

Bone Neoplasms

Bone scanning-osteogenic sarcoma. Correlation with surgical pathology.

This study was designed to evaluate the role of isotopic scanning in determining the local extension of osteosarcoma. During the period of the study, 13 patients wtih biopsy proven osteosarcomas were evaluated. The results indicated that in no case did the isotope scan demonstrate greater intramedullary extension of tumor than the routine roentgenographic examination. In addition, despite good correlation between the roentgenogram, scan, and histologic evaluation of tumor extent, all of which showed no evidence of malignancy near the area of surgery,there have been to date 3 local recurrences.

Adolescent

Multiple myeloma.

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Adult