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Biomedical subjects

K Burkhardt

Publications and source records attributed to K Burkhardt.

At least 55 records · Page 3Linked to original sources
PubMed1975

[Ampicillin concentrations in serum and bile after oral administration of ampicillin and pivampicillin].

The concentrations of active agent were determined in the bile and serum after oral administration of ampicillin and pivampicillin to 12 patients 7-9 days after surgical revision of the common bile duct. Orally, pivampicillin is more rapidly absorbed, maxima of active agent and the mean serum concentrations are higher compared with ampicillin. The rate of absorption and serum concentrations after giving ampicillin and pivampicillin depend on the type of diet. Pivampicillin produces higher concentrations of active agent in the bile of the common bile duct more rapidly than ampicillin. The mean concentration of active substance in the bile is distinctly above the serum concentrations.

Administration, Oral↗
PubMed1975

[Treatment of peptic esophageal stenosis in childhood].

Among a total of 82 children treated conservatively and surgically for hiatal hernia and gastro-esophageal malposition (Lortat-Jacob) 14 cases (17%) of peptic stenosis of the esophagus was observed. In an evaluation of the etiology of peptic esophageal stenosis the importance of anatomical growth and morphological changes of the cardia during infancy is stressed. Analysis of patient data revealed an unusually short period of stenotic manifestation after the first symptoms of reflux had been noted. Fundoplication with or without bouginage on an endless string seems to constitute the most beneficial form of therapy.

Adolescent↗