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Biomedical subjects

K Bolzano

Publications and source records attributed to K Bolzano.

At least 37 records · Page 2Linked to original sources
PubMed1978

[Biguanides: reasons for withdrawal of drugs and remaining indications].

The pharmacological properties and the mode of action of biguanides is presented. In Austria, the association of lactic acidosis with biguanide therapy has led to a cancellation of the registration of buformin and phenformin. Only, if all contraindications for biguanide therapy are strictly observed, metformin can be prescribed for the treatment of obese patients with type II diabetes.

Acidosis↗
PubMed1976

[Separate evaluation of left and right-sided renal function (author's transl)].

The PAH extraction of the kidneys was determined separately on each side after catheterisation of both renal veins and the femoral artery during PAH infusion in eleven patients with normal or diminished renal function due to bilateral renal disease and in five patients with only one kidney with normal or diminished renal function. A significant positive correlation was found between PAH extraction and inulin clearance and a significant negative correlation between PAH extraction and the log of the serum creatinine. PAH extraction is a suitable method for quantitative evaluation of right and left renal function.

Aminohippuric Acids↗
PubMed1976

[Prazosin--a new antihypertensive agent (author's transl)].

40 patients with essential hypertension of varying degrees were treated with prazosin for up to 6 months. Both in severe (n=10) and in moderately severe (n=28) hypertension a significant decrease of the systolic and diastolic blood pressure was observed after only one month of treatment. This effect was even more evident after 3 and 6 months. 18 patiets showed orthostatic disorders at the beginning of treatment which in all cases disappeared after several weeks. No side effects were observed which could be attributed with certainty to prazosin.

Adult↗