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Biomedical subjects

K Birkinshaw

Publications and source records attributed to K Birkinshaw.

8 recordsLinked to original sources
PubMed2003

Deconvolution of mass spectra measured with a non-uniform detector array to give accurate ion abundances.

Array detectors are under active development since they offer large improvements in the efficiency of mass spectrum measurements. High quality is always a requirement whether array detectors are used for ions, electrons, UV, x-rays, etc., but in mass spectrometry the very high accuracy frequently needed in ion abundance measurements for isotope ratios is unique. These demands necessitate modelling the measurement process and careful deconvolution of the measured data. A linear model in terms of matrix algebra is presented in which the incident spectrum (unknown) and the measured spectrum are represented by column matrices and the action of the detector array on the incident spectrum is represented by an experimentally measurable square 'A' matrix. Residual noise in this matrix can be minimized following a singular value decomposition procedure and its use in 'forward deconvolution' of measured spectra is discussed. The random error in the incident ion counts is accounted for after the deconvolution since this is not an error from the perspective of the detector. The microchannel plate electron multiplier gain distribution is an important feature of the deconvolution.

Algorithms↗
PubMed1978

Pre-operative approach to patients.

Thorough explanation of an operation can and should be given to a large number of patients. They are selected by a non-leading question once they have been assessed, and given a logical talk with simple drawings. A pilot questionnaire study shows that such a procedure is harmless and reassuring. It is justified as a supplement to the pre-medication but could well be done by other doctors, such as general practitioners or surgeons. Good explanation increases patient's confidence in the surgeon, never undermines it.

Humans↗
PubMedDate not supplied

The use of drawing.

A case is made for the use of plain drawing in communication between anaesthetists and patients, other doctors and administrators. Suggestions for the application of drawing to anaesthetic practice are made and notes on sending work for publications are provided.

Anesthesiology↗