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Biomedical subjects

K Beppu

Publications and source records attributed to K Beppu.

6 recordsLinked to original sources

An iatrogenic foreign body (dental bur) in the maxillary antrum: a report of two cases.

Two cases of foreign bodies of the antrum are reported. One was a turbine bur which presumably entered through an oro-antral fistula after a tooth extraction. The other was also a turbine bur where the mode of entry was not clear (lack of oro-antral fistula), but it presumably entered through the socket of the extracted tooth. The mucosa of the antrum appeared normal in spite of the lengthy presence of the foreign body.

Adult

Rosette formation of impacted molar teeth in mucopolysaccharidoses and related disorders.

The radiographic features of the jaws in the mucopolysaccharidoses and related disorders (MPS) have been reviewed and three further cases are reported here, with particular reference to a novel dental anomaly, not previously described in detail, in two of them. The dental changes appear to be fully developed by the third decade and are characterized by bilateral multiple impacted molar teeth, which conglomerate in a single follicle to form a characteristic rosette of teeth. Rosetting was present only in relatively mature cases of MPS. However, it was also seen in the fourth patient, where we could not detect any other abnormal clinical or radiographic features. We therefore propose that since multiple rosetting of molar teeth can also occur in an isolated form, it is only suggestive of MPS.

Adolescent

Postpalatoplasty decrease in respiratory dead space in young children.

In 20 children with cleft palates age 1.5 to 2 years, respiratory parameters were evaluated before, 15 minutes after, and 1 hour after palatoplasty. The dead space (VD) in the palatoplasty group decreased from 25.2 +/- 4.7 ml preoperatively to 12.3 +/- 9.1 ml postoperatively. This decrease improved respiratory efficiency. A significant difference was found postoperatively in the partial pressure of CO2 in arterial blood (PaCO2) between the palatoplasty and control groups. No significant differences were found in base excess (BE), arterial pH, pulmonary shunt ratio, and the alveolar-arterial O2 difference (A-aDO2) between the groups pre- and postoperatively. This finding indicated that temporary respiratory failure may exist postoperatively; the phenomena were improved in the recovery room. Since lung compliance and airway resistance may also participate in the decrease in VD, further evaluation of these factors are necessary.

Carbon Dioxide

An electron microscopic study of the steroid hormone receptor in uterine cells by the colloidal gold-labeled steroid hormone.

To study the localization of the progesterone and estradiol receptors by electron microscopy, the colloidal gold-labeled steroid hormones, intercalated with bovine serum albumin, were developed in the postembedding method. Among the tissues investigated in this study, receptors specifically distributed in the nuclei of the cells in the uterus and liver but not in the colon. Among the uterine smooth muscle cells in the estrus cycle, the frequency of the progesterone receptors in the nuclei indicated the highest level at a proestrus stage when the serum estradiol is maximum and the lowest level at a metestrus stage when the serum estradiol is minimum. On the other hand, the frequency of the estradiol receptor did not show significant changes among the stages of the estrus cycle. In the nuclei, the receptors specifically distributed on the euchromatin and on the peripheral regions of the heterochromatin, thought to be active regions of the transcription, and among the interchromatin granules. No receptors were observed within the nucleolus, the heterochromatin, the perinuclear chromatin, the nuclear sap, and the perichromatin granules. The colloidal gold-labeled steroids proved to be useful to study the microlocalization of the steroid hormone receptors in various target organs by electron microscopy.

Animals