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Biomedical subjects

K Benli

Publications and source records attributed to K Benli.

At least 37 records · Page 2Linked to original sources

The role of lipid peroxidation in the genesis of vasospasm secondary to subarachnoid hemorrhage.

The aim of this study is to find out the possible trigger role of lipid peroxidation in vasospasm. Haemoglobin-free washed erythrocyte membranes (erythrocyte ghost) corresponding to 2.5 mg membrane protein was mixed with 0.5 umol NADPH 3 umol ADP, 4 umol ferrous sulphate and injected into the cisterna magna of cats to stimulate lipid peroxidation in vivo (Group 1). The second group was injected lml/kg whole blood and the control group 1 ml/kg saline. Angiographic studies revealed significant vasospasm in five cats in group 1. Severe vasospasm was seen in six cats in group 2. A significant increase in lipid peroxidation was observed in groups 1 and 2, compared to the control group. These results may suggest that free radical products may play an important role in the complex genesis of vasospasm in subarachnoid haemorrhage.

Angiography↗

Giant congenital meningioma in a newborn.

The authors report the case of a giant meningioma in a 5-day-old newborn. Congenital meningiomas are extremely rare. Five newborns with meningiomas have been reported in the literature to date. This is the first case of a newborn with a giant meningioma with supra- and infratentorial and intraorbital components.

Brain Neoplasms↗

Malignant teratoma of the cerebellopontine angle: case report.

A case of malignant teratoma of the cerebellopontine angle is presented. Preoperative findings suggested an acoustic neurinoma or a meningioma. Particularly in adulthood, malignant teratomas arising in unusual locations can simulate common intracranial tumors.

Adult↗

Papillary carcinoma of the sphenoid sinus associated with sphenoid sinus abscess presenting as cavernous sinus syndrome. A case report.

Primary carcinoma of the sphenoid sinus is a rare tumor that may present with dramatic neuro-ophthalmological-symptoms and signs of which spheno-cavernous syndrome is the best known clinical entity. The most frequently encountered histological types of the sphenoid carcinomas are squamous cell carcinoma and papillary carcinoma, in decreasing order of frequency. In this article, a papillary carcinoma of the sphenoid sinus associated with sphenoid sinus abscess is presented. We are not aware of previously reported papillary carcinoma of the sphenoid sinus associated with sphenoid sinus abscess presenting as a cavernous sinus syndrome.

Abscess↗

Examination of autologous and embryonic cortical brain tissue transplantation to adult brain cortex in rats.

Autologous and embryonic cortical brain tissue was transplanted to adult rats in order to reconstruct experimentally degenerated cortical brain tissue. Rats were decapitated within 6 or 12 weeks. Viability of the graft tissues was studied by light and electron microscopy. Embryonic cortical brain tissue grafts became enlarged but adult cortical brain tissue grafts were found to be unaltered. Electron-microscopically observed mitochondria and other cell organellae and the newly vascularized areas clearly showed that the graft tissues were alive.

Animals↗

Fetal pituitary transplants into the hypothalamic area of hypophysectomized rats.

The pituitary tissue, when transplanted to extracerebral sites other than the normal anatomic position, fails to perform its secretory function properly. Several works on experimental intracerebral pituitary transplantation have shown that the transplanted tissue has been able to survive histologically. In this study, fetal pituitary tissue was implanted into the anterior hypothalamic area of the hypophysectomized rat by stereotactic methods. Electron-microscopic examination and hormonal blood levels demonstrated that ectopic pituitary tissue was able to survive to establish the correct anatomic relationship and thus perform secretory functions when transplanted intracerebrally.

Animals↗

Spinal meningiomas.

Between the years of 1970-1982 29 spinal meningioma cases were operated on; 22 cases (76%) were female and 7 (24%) were male. The youngest patient was 16, and the oldest was 68 years old. On neurological examination, patients had neurological deficits in varying degrees. Diagnosis were done by myelography in all cases. Laminectomy was performed in all cases. 34.4% of cases were situated in cervical region and 65.6% were in thoracic region. 14% of the tumours were located extradurally and 68% were intradural. Multiple spinal meningioma was seen in only one case. One case died after operation; the mortality rate is 4%. 22 cases came for follow-up examination, 86.5% of them were in excellent or good condition. Only three cases showed no improvement.

Adolescent↗

Chronic extradural haematoma: a late complication of head injury.

Three cases of chronic extradural haematoma are presented. The patients who were admitted with neurological signs, were fully conscious at the time of diagnosis. They were operated on 9, 14 and 29 days after the initial trauma. The necessity for adopting a generally accepted chronological criterion of chronicity for extradural haematoma is emphasized. A distinction between conscious and comatose patients with chronic extradural haematoma is made.

Adult↗

[Primary carcinoma of the choroid plexus. 2 case reports and review of the literature].

Primary Carcinomas of Choroid Plexus are seen rarely. In previous literature there were 37 cases which were reported according to Lewis and Russel-Rubinstein malignancy criterias. In this article, we describe 5 years old boy and 1.5 year old girl who suffered from cerebellar ataxia and intracranial pressure increase syndrome. In case 1, the tumor of the fourth ventricle was diagnosed by brachial angiography and ventriculography. In case 2, the diagnosis was established by CT scan. In case 1, the patient died during the postoperative course. In case 2, the postoperative time was unremarkable. A radiotherapy of 3 000 rads was applied to the posterior fossa. One year later, the patient had only mild ataxia.

Adolescent↗

[Intracranial ependymomas. Study of 81 cases and comparison with the literature].

For ten-years of period, between 1973-1982, 81 cases with intracranial ependymoma have been operated in H.U.T.F. Neurosurgery Department. Supratentorial localisation have been found in 24 cases (30%), and infratentorial in 57 (70%). 80% of the patients in supratentorial group and 91% in infratentorial group were under the age 20. In supratentorial group 79% were in paraventricular localisation, and 21% were intraventricular. In infratentorial group 70% of the cases were localised within the IV. ventricle, 20% in province of the tentorial roof, 5% in the lateral recessus and 5% into cerebellum. The 40 patients who were followed up were rated according to the localisation and the grades of the tumors, the type of the surgical intervention and chemotherapy with respect to the postoperative survival. As a result only the total resection of the tumor was found to be significant.

Adolescent↗

[Papilloma of the choroid plexus of the 3d ventricle. Report of a case and review of the literature].

It's rare for CPP to fill the III ventricule. Up to date, 24 cases surgically removed have been reported. In this report, we present a 1,5 year old boy who administered because of severe cachexia and reactive coma. Ct scan revealed dilatation in lateral ventricles and a mass totally filling the III ventricle. The mass has been totally excised through foramen Monro by right frontoparietal craniotomy and transcortical transventricular surgical approach. While a post-operative recovery was being observed, the patient died in the 30 the day because of bronchopneumonia. The treatment of III ventricle CPP as all the other CPP, must be total resection. For this reason, preoperative CT scan carries a great value about giving information of the nature of the tumor.

Cerebral Ventricle Neoplasms↗

Determination of aluminum levels in the kidney, liver, and brain of mice treated with aluminum hydroxide.

In the present study, aluminum (Al) accumulation has been examined after aluminum loading in mice. The kidney, liver, and brain aluminum levels for mice that had been treated orally with aluminum hydroxide for 105 d and for the control group were determined using graphite furnace atomic absorption spectrophotometry (GFAAS) following an acid digestion. Matrix modifier consisted of 2% Triton X-100 and 2% Mg (NO3)2. Al loaded mice showed a significant increase in tissue aluminum levels, relative to the control group.

Aluminum↗

Epidural metastasis of testicular yolk sac tumor: an unusual cause of spinal cord compression. Case report.

Testicular tumors in the pediatric age group are rare. Yolk sac tumor (YST) is the most common malignant tumor of germinal origin in this group, and it may spread to the retroperitoneal lymph nodes. We have been unable to find any previously published report of metastasis of testicular YST to the epidural space of the spinal cord presenting as a cause of spinal cord compression.

Child, Preschool↗

Craniosynostosis: a review of 143 surgically-treated cases.

In this study, 143 cases of craniosynostosis are presented. There were 109 males and 34 females. The major complaints were skull deformity (92 patients), proptosis (38 patients) and microcephalus (32 patients). Neurological examination revealed the presence of optic atrophy in 24 patients and papilledema in 20 patients. Seventy-four patients (53%) had three or more suture closures, with the sagittal suture being the most commonly involved (20% of patients). All patients underwent surgery. Suture removal was performed in 131 patients (91.7%), suture removal plus orbital decompression in 34 (23.8%), and linear craniectomy plus wrapping in 12 (8.3%). The reoperation rate was 6.2 percent. During the follow-up period, preoperative papilledema and proptosis improved in 88.2 and 78.9 percent of patients, respectively. Skull deformity disappeared in 46.9 percent of patients, but remained unchanged in 16.6 percent.

Child↗