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K Barta

Publications and source records attributed to K Barta.

12 recordsLinked to original sources
PubMed1993

Nurses' knowledge of--and role in--patients' end-of-life decision-making.

The Code for Nurses as set forth by the American Nurses Association promotes the nurse as the patient's advocate protecting his/her rights and preventing unwanted intrusion, but based on the results of this study, the nurse is unprepared to be such an advocate. This may be due to a lack of knowledge about the law or a lack of confidence in discussing the issue with patients. The best time and place to prepare an advance directive are still in question. The point of admission into the hospital or other health care institution may be the time to verify the existence of an advance directive, but it is probably not the best time or place to construct one. This was reinforced by comments noted by the subjects responding to the questionnaire. Nurses may have an important role in the process, but this research shows that nurses do not feel comfortable talking about advance directives to patients and families. However, nurses need to be prepared to talk to the patient and family about this very important process and to operationalize their end-of-life decisions. Academic and health care institutions should assist nurses in gaining the knowledge and the confidence needed for this process.

Adult↗
PubMed1974

Role of genetic recombination in DNA replication of bacteriophage lambda. I. Genetic characterization of the delta gene.

We describe the isolation and genetic characterization of point mutations in gene delta, including a temperature-sensitive mutation (del(206)). Genetic methods enable the extraction of a delta mutation from the triple mutant (del,red,gam) and the construction of new genotypes, including del,red and del,gam double mutants. Tests of plating efficiency indicate gene delta is essential for normal phase growth on the polA host. The possible association of delta in a system involving alpha, beta, and gamma is considered.

Coliphages↗
PubMed1974

Role of genetic recombination in DNA replication of bacteriophage lambda. II. Effect in DNA replication by gene delta.

We have studied the effect of delta mutations in phage lambda on DNA synthesis as assayed by the accumulation of lambda DNA in infected cells. We find that delta mutants appear to generate somewhat less DNA than lambda(+) in a rec(+) host, suggesting the wild-type delta gene may act in DNA replication. An additional clue to delta function arises if replication is measured in the gamma-negative situation where concatemer formation is abortive. In this situation, the wild-type delta gene has an "inhibitory" effect on replication. A similar inhibitory effect on replication due to delta is observed after infection of P(2) lysogens. We conclude from these studies that the delta gene may act with alpha, beta, and gamma genes, possibly in a process affecting DNA replication.

Coliphages↗