Prolonged bradycardia and hypotension after neostigmine administration in a patient receiving atenolol.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to K B Shankar.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The physiological dead space and its components were determined during general anaesthesia for Caesarean section in seventeen patients and compared with similar values for seventeen patients undergoing abdominal hysterectomy under general anaesthesia. The physiological dead space was smaller in the pregnant patients, due to a smaller alveolar dead space. The anatomical dead space was similar in both groups. A lowered physiological dead space suggests that there will be a decrease in the pulmonary ventilation perfusion ratio (V/Q) during Caesarean section; this could result from better perfusion of the ventilated alveoli than in the non-pregnant group, due to the increased cardiac output of pregnancy. An improvement in alveolar perfusion should also produce more efficient carbon dioxide elimination in pregnant patients, when compared to non-pregnant subjects.
Twenty-nine patients scheduled for postnatal tubal ligation by minilaparotomy under general anaesthesia were studied. Arterial and end-tidal carbon dioxide tensions were determined during anaesthesia. The mean arterial to end-tidal carbon dioxide tension difference was 0.08 kPa (SEM 0.05). Thirty-one percent of the patients had negative values. These results were similar to those observed during Caesarean section. The physiological changes responsible for reduced arterial to end-tidal carbon dioxide values, persist into the postnatal period. It is predicted from the regression analysis of the time between delivery and anaesthesia for tubal ligation and arterial to end-tidal CO2 difference, that the values might return to normal nonpregnant levels by 8 days following delivery.
We studied the relationship between arterial carbon dioxide tension (PaCO2) and fresh gas flow (FGF) during use of the Bain breathing circuit for Caesarean section anaesthesia. Thirty-one patients undergoing Caesarean section were anaesthetised using the Bain circuit with intermittent positive pressure ventilation. The PaCO2 were measured at FGF of 70 ml X kg-1 X min-1, 80 ml X kg-1 X min-1, and 100 ml X kg-1 X min-1. The FGF requirement to maintain a given PaCO2 during Caesarean section anaesthesia is the same as the requirements for nonpregnant subjects, despite the increase in carbon dioxide production associated with pregnancy. This is probably because the total FGF determined by body weight and given during Caesarean section anaesthesia is 15-20 per cent higher than nonpregnant levels, due to the weight gain associated with pregnancy. A FGF of 100 ml X kg-1 of pregnant weight/min maintains PaCO2 of 4.44 kPa predelivery, which is in the desirable range of PaCO2 during Caesarean section.
The relationship between arterial carbon dioxide tension and end tidal carbon dioxide tension was studied in 19 patients during general anaesthesia for Caesarean section. Thirteen patients scheduled for elective abdominal hysterectomy formed a nonpregnant group. There was significant correlation between arterial and end tidal CO2 tensions in both groups. During Caesarean section, this difference was significantly less than in the nonpregnant group.
Explore the source record for details and available documents.