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Biomedical subjects

K Anger

Publications and source records attributed to K Anger.

At least 37 records · Page 2Linked to original sources
PubMed1980

[Quantitative whole-body bone scintigraphy. III. Clinical significance for the diagnosis of bone metastases, systemic bone diseases and diseases of the joint (author's transl)].

Quantitative whole-body bone scans were performed on 277 patients with bone metastases, diseases of the joint and systemic bone diseases in order to evaluate the clinical significance of quantitative and kinetic data in bone imaging. Metastases and other focal bone diseases are recognizable and quantifiable by the method; however, sensitivity and specificity of bone imaging are not enhanced. In metabolic bone diseases, with the exception of osteoporosis, kinetic data facilitate the analysis of bone scans. Typical signs of osteomalacia, hyperparathyroidism and renal osteodystrophy--increased retention of the activity in the skeleton and increased bone/soft tissue ratios as well as a generally changed distribution of radioactivity--are only recognizable by quantitative imaging.

Adolescent↗
PubMed1980

[Quantitative whole-body bone scintigraphy. II. Pharmacokinetics of osteotropic radiopharmaceuticals (author's transl)].

85Sr, 99mTc-Sn-pyrophosphate and 99mTc-Sn-methylene-diphosphonate, the most important agents for skeletal imaging, are compared with each other by calculation of the plasma clearance and the urinary excretion and by a series of quantitative whole-body scans. 85Sr the distribution volume in equilibrium is the largest, shifting of activity is demonstrable for several days after injection. 99mTc-Sn-MDP is excreted most quickly, equilibrium is reached early. There is no significant difference in skeletal uptake between the phosphate complexes. The distribution however is different: 85Sr is localized to a greater extent in the extremities, the phosphate complexes more in the trunk, 99mTc-Sn-MDP and 85Sr nearer the joints than 99mTc-Sn-pyrophosphate.

Bone and Bones↗
PubMed1977

[First clinical experience with axial emission computer tomography (author's transl)].

104 examinations were carried out on 81 patients with a new commercial emission computer tomographic scanner. The technique provides additional information in half the brain scans, but only in one third of liver scans. No indications for this examination could be discovered in a relatively small clinical material for the examination of the kidneys or the skeleton. Other organs were not included in this assessment. The authors confirm reports in the literature which show that this method is not particularly valuable for finding pathology. It finds its application in conforming or excluding suspected abnormalities and for better localisation and delineation of lesions, thereby aiding differential diagnosis. However, further technical improvements and increased clinical experiency may increase the applicability of the technique.

Brain Neoplasms↗
PubMed1976

Behavior changes during repeated eight-day extinctions.

Pigeons were given repeated two-day conditionings alternating with eight-day extinctions using a trial procedure. One group had different key colors during each of the first five conditioning-extinction pairs; another group had the same key color throughout. Total extinction responses of both groups were quite constant over successive extinctions. This finding differs from the rapid declines found in most previous studies with bar-press and key-peck responses. The difference probably was due to our longer extinctions, because responses early in each extinction did decrease. However, that decrease was neutralized by increases in responses late in each extinction. The two opposite changes indicate the influence of two different factors during repeated extinctions, with neither factor having much stimulus specificity. The reduction of early responses may result from feeding changes confounded with extinction. The increase in later extinction responses may result from a decrease in the effect of unreinforced responses after their repeated occurrence.

Journal Article↗
PubMed1976

[Determination of spleen size by roentgenographic and nuclear medicine methods (author's transl)].

Knowing the splenic size is important in many medical diseases. This paper describes methods how to measure the size of the spleen by palpation, scan and a roentgenogram with soft tissue technique. In 486 normals medium splenic length was 12,8 +/- 1,9 cm measured roentgenographically. In 60 patients with splenomegaly the correlation coefficient between roentgenologically determined size and scintigraphically measured splenic length was 0,89, between radiologically determined size and estimated splenic weight by scan was 0.69. Nuclear medicine methods are important for exact evaluation of the size of the spleen, roentgenography is adequate in screening and control examinations.

Anthropometry↗
PubMed1972

The effect of discrimination training on responses to a new stimulus.

Most previous research on the effect of the duration of preceding discrimination training on responding to a new stimulus has measured the responding during extinction. To reduce effects originating in the extinction procedure itself, the present study assessed the effect of discrimination training on responses to a new negative stimulus added during continued discrimination training. Pigeons were given a new negative stimulus (blue key) after 0, 1, 3, or 9 days of discrimination training with a yellow key as the positive stimulus, and both a green key and a red key as negative. Fewer responses were made to the blue key when it was introduced after nine days of discrimination training than after less discrimination training. That effect of long discrimination training agrees with reported results from extinction tests. However, the effect of briefer discrimination training in the present study differed from reported results with extinction testing. It appears that testing during continued discrimination training eliminates a distortion present in extinction tests of the effect of discrimination training on responding to a new stimulus.

Journal Article↗