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Biomedical subjects

K A Kappy

Publications and source records attributed to K A Kappy.

8 recordsLinked to original sources

Premature rupture of the membranes at term. A comparison of induced and spontaneous labors.

Analysis of 150 patients at term (greater than 36 weeks) with premature rupture of the membranes (PROM) was made. In the group followed conservatively, 87.5% (98 of 112) began labor within 48 hours, and only 3.6% (4 of 112) had a latent period of greater than seven days. The incidence of cesarean section in patients with induced and spontaneous labors was compared in corrected groups. The induced group had a 39% (15 of 38) cesarean section rate as compared to 12% (11 of 91) in the spontaneous labor group (p = less than 0.01). None of the patients in the study showed signs of sepsis by central cultures, and only 12.7% (19 of 150) showed febrile morbidity. A conservative approach to term patients with PROM and an unfavorable cervix for induction seems to decrease the incidence of cesarean section.

Cesarean Section

Vacuum extractor.

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Extraction, Obstetrical

Amniotic fluid optical density and neonatal respiratory outcome.

A simple, rapid, economical, and accurate test to assess fetal pulmonary maturity on a 24-hour basis, 7 days a week, is urgently needed. A 15-minute test has been developed that correlates well with fetal pulmonary maturity. Optical density (OD) readings at 650 nm of greater than or equal to 0.15 in pigment-free, centrifuged (2000 Xg, 10 minutes) amniotic fluids obtained from gestations of 33 to 42 weeks correlate with fetal pulmonary maturity (131 of 131, 100%). When OD readings are less than 0.15 in fluids from gestations of 24 to 40 weeks, and antepartum steroids are utilized, the incidence of respiratory distress syndrome (RDS) is 8.3% (14 of 169). The true false-negative rate in this group is therefore unknown.

Amniotic Fluid

Prognostic components of the nonreactive nonstress test.

From January 1976 to November 1978, 2592 nonstress tests were performed at the authors' institution on 862 fetuses, of which 2239 (86.3%) had reactive and 353 (13.6%) had nonreactive results. Of these 862 fetuses, 842 were delivered at the authors' hospital. Of these 842 fetuses, 109 were delivered within 1 week of a nonreactive tracing and 733 were delivered within 1 week of a reactive tracing. A retrospective analysis was performed on 102 of the nonreative tracings done within 1 week of delivery to assess the significance of various components of the nonstress test on the subsequent stress test and perinatal outcome. No significant difference could be observed in the number of fetal movements and total number of accelerations as compared with the subsequent stress test. However, the nonreactive tracings of the contraction stress test (CST)-positive group differed from those of the CST-negative groups in number of accelerations over 15 beats per minute (38% versus 48%) (P < .05) and in the number of accelerations lasting longer than 20 seconds (20% versus 50%) (P < .01). The number of nonreactive fetal movements per test (2.6 versus 0.96) (P < .05) and the percentage of nonreactive fetal movements (33% versus 15%) (P < .01) were different in both groups. The growth-retarded fetus in the nonreactive group did not differ in the number of fetal movements or total accelertions when compared to fetuses born appropriate for gestational age, but the number of accelerations was more than 15 beats per minute (26% versus 50%) (P < .01) and the number of accelerations lasting 20 seconds (11% versus 28%) (P < .01) did differ significantly.

Delivery, Obstetric

Premature rupture of the membranes: a conservative approach.

A conservative approach was followed in 188 patients with premature rupture of the membranes (PROM) over a 2 year period. There were no neonatal deaths from sepsis, and only one infant showed a positive central bacteriologic culture. Fifty-seven percent of all patients less than 37 weeks' gestation had a latent period of 24 hours and 19% went beyond 7 days before labor began. Patients less than 34 weeks' gestation who received antepartum steroids for lung maturation showed no increased infectious morbidity or mortality. A conservative approach to patients with PROM seems reasonable when either prematurity and/or a cervix unfavorable for induction further complicates the pregnancy.

Delivery, Obstetric

24-hour urine creatinine excretion in pregnancy.

A total of 489 consecutive 24-hour urine collection from 162 patients were analyzed for creatinine excretion. The 24-hour creatinine excretion increased with the urine volume. Creatinine excretions in 24-hour urine collections were not statistically different between in- and out-patients. The results indicate that the mean urine creatinine per 24 hours is 1.08 g for 24-hour urine volumes between 500 and 1500 ml. For urine volumes greater than 1500 ml it is 1.22 g. For 24-hour urine volumes less than 500 ml, the mean creatinine is 0.63 g.

Creatinine