Formal resuscitation training in medical school.
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Curriculum↗
Biomedical subjects
K A Handal
Publications and source records attributed to K A Handal.
Naloxone.
Naloxone hydrochloride, a synthetic N-allyl derivative of oxymorphone, is an effective agent for the reversal of the cardiovascular and respiratory depression associated with narcotic and possibly some non-narcotic overdoses. It is essentially a pure narcotic antagonist, is relatively safe, and is a useful diagnostic and therapeutic agent. Due to naloxone's pharmacokinetic profile, a continuous infusion protocol is recommended when prolonged narcotic antagonist effects are required. The complex pharmacodynamics of naloxone, specifically relating to endorphin receptor sites, focus its potential use in a variety of clinical situations as continuing research illustrates the association of endogenous opioid compounds with various disease states.
Adult↗
The lower esophagus and glucagon.
A bolus impaction of the lower esophagus in a 54-year-old woman was rapidly and safely relieved by the administration of intravenous glucagon. This case report reviews a known but little appreciated use of this drug. The history, pharmacology, and uses of glucagon are discussed.
Esophageal Diseases↗