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Biomedical subjects

K A Dunn

Publications and source records attributed to K A Dunn.

At least 37 records · Page 2Linked to original sources
PubMed1996

Contaminated wounds: infection rates with subcutaneous sutures.

STUDY OBJECTIVE: To determine whether buried absorbable subcutaneous sutures (BASS) increase the infection rate in irrigated contaminated wounds. METHODS: This was a randomized, prospective trial in a rat model, with the histologist blinded to treatment group. A single 2-cm dorsal incision was made on each of 30 anesthetized 250-g Sprague-Dawley rats and inoculated with approximately 10(8) organisms of Staphylococcus aureus. After irrigation, 15 wounds were closed with running 4-0 nylon transdermal sutures, and 15 were closed with three interrupted 4-0 coated polyglactin 910 (Vicryl) subcuticular sutures (BASS) and running 4-0 nylon transdermal sutures. On day 7, wounds were scored on a scale of 0 to 3 in six categories: inflammatory infiltrates, fibroplasia and capillary proliferation, necrosis, exudates, giant cells, and edema. The possible range for the cumulative wound score was 0 (no inflammation) to 18 (severe inflammation and infection). RESULTS: The median total wound score in wounds closed with BASS was 14 (range, 7 to 16); it was 8 (range, 5 to 15) for wounds closed without BASS (P = .0004). The subscores for inflammation, necrosis, exudate, and edema were also significantly higher in wounds closed with BASS. CONCLUSION: BASS increase the infection rate and the degree of inflammation in contaminated wounds, despite through irrigation.

Animals↗
PubMed1996

Work patterns and occupational hazard exposures of North Carolina adolescents in 4-H clubs.

OBJECTIVES: This study documents sex differences in work patterns, injuries, and hazard exposures among adolescents in homes, farms, and other work sites. METHODS: 14 to 17 year old 4-H club members were asked to complete self administered questionnaires regarding their lifetime experience of work, hazard exposure, and injuries. RESULTS: Of 323 respondents, more than two thirds had ever worked paid jobs. Fifty seven per cent were injured during non-farm work and hazards were part of the non-farm work environment for 54% of the respondents. Males were more likely to work in hazardous conditions, including operating heavy equipment on farms or construction sites. Almost three quarters of the teens who worked on farms reported being injured there and 100% were exposed to at least one farm hazard. CONCLUSIONS: Adolescents perform jobs at homes, farms, or other work sites where they are exposed to numerous safety hazards. Prevention efforts should target specific hazards youths are exposed to rather than the general work site.

Accidents, Occupational↗
PubMed1995

Discharge instructions: do illustrations help our patients understand them?

STUDY OBJECTIVE: To determine whether the addition of illustrations to discharge instructions improves patient comprehension. DESIGN: Randomized, blinded, prospective study. A blinded investigator asked a series of questions designed to test the participant's comprehension of the discharge instructions. There were 10 possible correct responses. SETTING: Emergency department of a rural Level I trauma center. PARTICIPANTS: Convenience sample of 101 patients discharged with the diagnosis of laceration. INTERVENTIONS: Patients were randomly assigned to receive discharge instructions with (n = 54) or without (n = 47) illustrations. RESULTS: The median number of correct responses was five. Patients with illustrations were 1.5 times more likely to choose five or more correct responses than those without illustrations (65% versus 43%; P = .033). The effect of illustrations varied by demographic group. Among nonwhites (n = 51), patients with illustrations were more than twice as likely to choose five or more correct responses (P = .032). Among patients with no more than a high school education (n = 71), patients with illustrations were 1.8 times more likely to choose five or more correct responses (P = .038). Among women (n = 48), patients with illustrations were 1.7 times more likely to chose five or more correct responses (P = .006). CONCLUSION: The addition of illustrations to discharge instructions for patients who have sustained lacerations improves patient comprehension. There is a large effect among patients who are nonwhite, female, or have no more than a high school education.

Audiovisual Aids↗
PubMed1995

Conference attendance: do we meet the new residency review committee requirements?

STUDY OBJECTIVES: To characterize the attendance at and presenters of conferences given to emergency medicine residents and to determine the ability of emergency medicine residents to attend conferences while working in the emergency department and on off-service rotations. DESIGN: Descriptive study of an anonymous mail survey. PARTICIPANTS: Residency directors of all approved emergency medicine residency programs in the United States. RESULTS: Seventy-six of 95 questionnaires (80%) were returned. We defined "high attendance" at emergency medicine conferences as a reported average of at least 75% attendance by emergency medicine resident physicians. Fifty percent of respondents reported high attendance. Conversely, 17% of programs reported poor attendance, which we defined as an average attendance by 50% or fewer emergency medicine resident physicians. Forty-eight percent of programs reported that emergency medicine faculty conducted more than 50% of the conferences, and 16% reported that the faculty conducted 25% or fewer conferences. Ninety-six percent of programs allowed residents to attend conferences during off-service rotations. Ninety-two percent of programs relieved residents of clinical responsibilities during scheduled shifts in the emergency department so that they might attend lectures. CONCLUSION: We found that a sizable proportion of programs may not have met the new Residency Review Committee requirements for lecture attendance at the time the guidelines were issued. The vast majority of programs met guidelines for relief of clinical duties, and a large proportion of programs exceeded the requirements for percentage of lectures given by emergency medicine faculty.

Emergency Medicine↗
PubMed1995

Subcuticular sutures and the rate of inflammation in noncontaminated wounds.

STUDY OBJECTIVE: To determine whether buried, absorbable, subcuticular sutures increase the degree of inflammation in noncontaminated wounds. DESIGN: Randomized, blinded, prospective trial. SETTING: Laboratory. PARTICIPANTS: Eleven Sprague-Dawley rats weighing 300 to 325 g. INTERVENTIONS: Four wounds were made on each rat. Two wounds on each were closed with three interrupted buried, absorbable, subcuticular sutures 6-0 polyglactin 910 and running 5-0 nylon skin sutures. The other two wounds were closed with running 5-0 nylon skin sutures alone. RESULTS: Fourteen days after the sutures were placed, the animals were killed, and histologic preparations were made from each wound. Each sample was scored on a scale of 0 to 3 for the presence of inflammatory infiltrates, fibroplasia and capillary proliferation, necrosis, exudates, giant cells, and edema. We determined a total wound score by adding the scores from each category. The mean total wound score was 4.46 +/- 2.92 for those closed with buried, absorbable, subcuticular sutures and 4.91 +/- 2.56 for those closed without buried, absorbable, subcuticular sutures. Using the Wilcoxon rank-sum test, we found no statistically significant difference in mean total wound score of wounds closed with and without buried, absorbable, subcuticular sutures (alpha = .01). The probability of detecting a twofold difference in total wound scores was 60% (beta = .40). CONCLUSION: Buried, absorbable, subcuticular sutures do not significantly increase the degree of inflammation in noncontaminated wounds.

Animals↗
PubMed1995

A new model for teaching corneal foreign body removal.

OBJECTIVE: To determine whether a skills laboratory for corneal foreign body and rust ring removal improves self-assessed skill and confidence. METHODS: A prospective trial was conducted as part of the didactic curriculum of a university-based residency program in emergency medicine (EM). A convenience sample of 26 EM residents and five fourth-year medical students participated. The skills laboratory used model corneas made by coating 3.2-cm glass spheres with a 1-2-mm film of paraffin. Foreign bodies were simulated by embedding small pieces of metal into the paraffin. Rust rings were simulated by dipping a hot, straightened paper clip into a rust-colored crayon and then into the paraffin. The model eyes fit into a life-sized model of a human head. Participants removed the foreign bodies and rus rings under supervision, using the slit lamp. Each participant anonymously completed a questionnaire before and after participating in the skills laboratory. The questionnaire recorded educational level, previous experience, and self-assessed comfort and skill levels (0 = lowest, 10 = highest). RESULTS: Most (66%) of the participants had not previously removed a corneal foreign body; 86% had not previously removed a rust ring. On a ten-point scale, the median comfort level for removing a foreign body rose from 2 to 7, and the self-assessed skill level rose from 1 to 7 (p = 0.0001). Similar improvements in self-assessed comfort and skill levels were seen for rust ring removal. CONCLUSIONS: Participation in this skills laboratory significantly improved the self-reported comfort and self-assessed skill levels in removing corneal foreign bodies and rust rings. This technique provides useful practice of a fine-motor procedural skill requiring eye-hand coordination prior to supervised application of these skills in clinical practice.

Adult↗
PubMed1993

Deaths at work among children and adolescents.

OBJECTIVE: To identify and describe all nonmilitary on-the-job injury fatalities in North Carolina among persons younger than 20 years over 10 years, with special attention to potential violations of the Fair Labor Standards Act. DESIGN AND SETTING: Historical, population-based case series, with cases identified by the computerized files of the North Carolina Office of the Chief Medical Examiner. CASES: Persons younger than 20 years who died of injuries received on the job in North Carolina between January 1, 1980, and December 31, 1989. RESULTS: We identified 71 cases. Decedents ranged in age from 11 to 19 years, with 41% aged 17 years or younger. Cases were disproportionately male (90%), white (80%), and injured during June, July, and August (44%). Farm or field was the most frequent place of injury (27%). More than 50% of injuries involved a motorized vehicle, frequently a tractor. Similar to studies in adults, homicide was the leading cause of fatal occupational injury for females. At the time of injury, 86% of workers younger than 18 years were involved in activities that appeared to violate the Fair Labor Standards Act of 1938. CONCLUSIONS: This study raises questions about the adequacy of federal child labor policies as minors continue to work under conditions that place them at risk for fatal injuries.

Accidents, Occupational↗
PubMed1993

Injury prevention instruction in the emergency department.

STUDY OBJECTIVE: To describe preventable pediatric injuries and the proportion receiving documented injury prevention instruction by emergency department personnel. DESIGN: Retrospective chart review. SETTING: A rural Level I trauma center. TYPES OF PARTICIPANTS: All injured children aged birth through 15 years presenting to our hospital from January 1, 1987, through December 31, 1987. MEASUREMENTS AND MAIN RESULTS: During the study period, 1,449 injuries presented to the trauma center. Motor vehicle crashes caused the largest number of preventable injuries (71), although the proportion of preventable injuries was higher among poisonings, burns, and pedestrian-automobile collisions. Among the 1,313 patients available to ED personnel at discharge, injury prevention instruction was indicated in 27% of cases but documented in the medical record in only 3%. ED personnel were more likely to document instruction for preventing poisoning than other causes of injury. CONCLUSION: Most preventable pediatric injuries treated and released by ED personnel do not receive documented injury prevention instruction.

Adolescent↗
PubMed1991

Lightning fatalities in North Carolina 1972-1988.

Individuals who are outdoors during thunderstorms are at risk for death from direct and indirect lightning hits. Death is more likely from 3:00 p.m. to 8:00 p.m. during the months of May through September. The fatality pattern in North Carolina is similar to that reported for the nation as a whole. Physicians are urged to discuss with their patients simple strategies for reducing exposure to lightning.

Adolescent↗
PubMed1987

A panel approach to the evaluation of the sensitivity and specificity of antibodies for the diagnosis of routinely processed histologically undifferentiated human neoplasms.

The evaluation of antibodies for diagnostic purposes on routinely processed sections of histologically undiagnosable neoplasms presents special problems. The authors have addressed this problem by constructing a panel of putatively mutually exclusive antibodies and testing it on sections of anaplastic neoplasms. Tissue sections of 120 routinely processed histologically undifferentiated large cell human neoplasms with a histologic differential diagnosis of carcinoma versus lymphoma and/or melanoma were stained with a panel of antibodies composed of monoclonal antikeratin AE1, monoclonal antileukocyte common antigens PD7/26 and 2B11, and rabbit anti-S-100 protein. Only cases not diagnosable by routine morphologic examination were included. PD7/26 and/or 2B11 were positive in 61 cases (supporting lymphoma), AE1 was positive in 17 cases (supporting carcinoma), and anti-S-100 was positive in 25 cases (supporting melanoma). Seventeen neoplasms failed to react with any of the panel antibodies. None of the neoplasms reacted with antibodies directed against two or more different antigens. These results indicate excellent specificity (100%) and good sensitivity (86%) of the panel antibodies on histologically undifferentiated neoplasms. These results are significant on two levels: first, as a test of the panel approach to evaluate antibodies on anaplastic neoplasms, and, second, as a demonstration of the diagnostic utility of the specific panel the authors have employed in such cases.

Antibodies, Monoclonal↗
PubMedDate not supplied

EMS knowledge and skills in rural North Carolina: a comparison with the National EMS Education and Practice Blueprint.

INTRODUCTION: Many state and local emergency medical services (EMS) systems may wish to modify provider levels and their scope of practice to align their systems with the recommendations of the National Emergency Medical Services Education and Practice Blueprint. To determine any changes that may be needed in a typical EMS system, the knowledge and skills of EMS providers in one rural area of North Carolina were compared with the knowledge and skills recommended in the National Emergency Medical Services Education and Practice Blueprint. METHODS: A survey listing 175 items of patient care-oriented knowledge and skills described in the National Emergency Medical Services Education and Practice Blueprint was developed. EMS providers from five rural eastern North Carolina counties were asked to identify on the survey those items of knowledge and skills they believed they possessed. The skills and knowledge selected by the respondents at the five different North Carolina levels of certification were compared with the knowledge and skills listed for comparable provider levels delineated by the National Emergency Medical Services Education and Practice Blueprint. The proportions of the recommended skills reported to be possessed by the respondents were compared to determine which North Carolina certification levels best correlate with the Blueprint. RESULTS: One hundred forty-five EMS providers completed the survey. The proportion of recommended skills and knowledge reported to be possessed by Emergency Medical Technicians (EMTs) ranked significantly lower than did the skills and knowledge reported to be possessed by respondents at other levels in five of the 10 Blueprint elements. The proportion of recommended skills and knowledge reported to be possessed by EMT-Defibrillator-level personnel ranked lower than did those reported to be possessed by respondents at other levels in seven of the 10 Blueprint elements. The proportion of recommended skills and knowledge reported to be possessed by EMT-Intermediates ranked lower than did those reported to be possessed by respondents at other levels in nine of the 10 Blueprint elements. The proportion of recommended skills and knowledge reported to be possessed by EMT-Advanced Intermediates ranked lower than were the skills and knowledge reported to be possessed by respondents at other levels in two of the 10 Blueprint elements. Finally, the proportion of recommended skills and knowledge reported to be possessed by EMT-Paramedics ranked lower than were those reported to be possessed by respondents at other levels in one of the 10 Blueprint elements. CONCLUSION: In North Carolina, combining the EMT and EMT-Defibrillator levels and eliminating the EMT-Intermediate level would create three levels of certification, which would be more consistent with levels recommended by the Blueprint. The results of this study should be considered in any effort to revise the levels of EMS certification in North Carolina and in planning the training curricula for bridging those levels. Other states may require similar action to align with the National Emergency Medical Services Education and Practice Blueprint.

Certification↗
PubMedDate not supplied

Prevalence and nature of allergy and chemical sensitivity in a general population.

The objectives of this study were (a) to determine the self-reported prevalence of allergy and chemical sensitivity in a rural population of eastern North Carolina, (b) to determine the type and frequency of symptoms for each condition, and (c) to determine the demographic groups affected. A random general telephone survey was conducted during the period May 14, 1993, to September 10, 1993, and questions about allergy and chemical sensitivity were asked. Of the 1 446 households contacted, 1 027 (71%) individuals agreed to participate. Allergies were reported by 365 (35%) individuals. Thirty percent of allergic individuals reported that symptoms occurred once or more each week, whereas 61% reported that symptoms occurred, at most, once each month. Allergic symptoms that occurred daily were reported by 5.3% of the total population. Chemical sensitivity was reported by 336 (33%) individuals. Thirty-five per cent of chemically sensitive individuals reported symptoms at least once each week, whereas 53% reported that symptoms occurred once (or less) each month. Symptoms of chemical sensitivity that occurred daily were reported by 3.9% of the total population. Both allergy and chemical sensitivity were distributed widely across age, income, race, and educational groups. Simultaneous allergy and chemical sensitivity were reported by 16.9% of the population, allergy without chemical sensitivity by 16.0%, chemical sensitivity without allergy by 18.2%, and neither condition by 48.9%. If the prevalence of sensitivity to chemical irritants is, in fact, equivalent to that of allergy, as was found in this study, then support for the scientific investigation of chemical sensitivity is justified.

Adolescent↗
PubMedDate not supplied

Influence of demographic variables in prehospital treatment of patients with chest pain.

OBJECTIVE: To determine whether the number of interventions requested by EMS personnel for patients with acute, nontraumatic chest pain varied with the patient's gender or race. METHODS: The authors conducted a retrospective chart review of the care requested for patients 17 years old or older complaining of acute, nontraumatic chest pain by one EMS squad in a city of 50,000 people over a six-month period. Interventions recorded for each patient included oxygen administration, artificial airway placement, intravenous fluid administration, defibrillation, and use of lidocaine and nitroglycerin. RESULTS: Of the 169 patients in this study, 54% (n = 92) were white and 56% (n = 95) were female. Age was missing for two patients; of the remainder, 75% (n = 127) were 40 years old or older. The numbers of interventions requested ranged from 0 to 4. EMS personnel requested supplemental oxygen for 163 patients. 81% of the females had i.v. lines placed or attempted, compared with 70% of the males; EMS personnel requested orders for nitroglycerin for 43% of the females and 29% of the males. Whites were more likely than nonwhites to have requests for i.v. lines or nitroglycerin. Overall, the numbers of interventions were similar among young females and among older patients, regardless of race or gender. The pattern for young males was different, with significantly more requests for interventions for young white males than for young non-white males (1.89 vs 1.34). CONCLUSIONS: Among older patients and among young females, EMS personnel requested similar numbers of interventions for patient complaining of acute, nontraumatic chest pain regardless of patients race. Patterns of care appeared to differ for young males, a finding that warrants further study.

Acute Disease↗
PubMedDate not supplied

The perceived importance of paramedic skills and the emphasis they receive during EMS education programs.

OBJECTIVE: The National Standard Curriculum for paramedics is currently being revised. There is little scientific evidence of what does and what does not work in prehospital care, and of whether the National Standard Curriculum prepares paramedics for the field. To provide some basis for the current revisions to the National Standard Curriculum, the authors determined which prehospital skills are perceived by paramedics to be the most important, and whether the emphasis placed on those skills during initial and continuing education programs corresponds with the perceived importance. METHODS: Surveys listing 21 paramedic skills were mailed to the directors of 41 EMS agencies who agreed to participate in the study. The directors distributed the surveys to 1,364 paramedics affiliated with their organizations. The participants were asked to rate the importance of each skill, and the emphasis placed on each skill during their initial and continuing education. Skills were ranked on a scale of 0 to 4, with 0 representing no importance or emphasis, and 4 representing the most possible importance or emphasis. RESULTS: Six-hundred of the 1,364 (44%) surveys were returned. Respondents had a mean of 9.9 +/- 5.6 years of EMS experience, and 5.4 +/- 4.0 years of experience as paramedics. The three skills ranked highest in importance were: 1) endotracheal intubation; 2) defibrillation; and 3) assessment. Importance in prehospital care was ranked equal to or higher than emphasis in both initial and continuing education for all skills except splinting and urinary catheterization, which received higher rankings for emphasis in initial education. Emphasis in initial education equaled or exceeded the emphasis in continuing education for all skills except intraosseous infusion. CONCLUSION: The perceived importance of most prehospital skills is very high, and exceeds the emphasis placed on those skills during both initial and continuing education programs. These findings have implications for medical directors, EMS instructors, and persons involved with the revision of the National Standard Curriculum.

Clinical Competence↗