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Biomedical subjects

Joseph C McDonald

Publications and source records attributed to Joseph C McDonald.

16 recordsLinked to original sources

Open access.

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Access to Information↗

A variable-energy electron microbeam: a unique modality for targeted low-LET radiation.

We have designed and constructed a low-cost, variable-energy low-LET electron microbeam that uses energetic electrons to mimic radiation damage produced by gamma and X rays. The microbeam can access lower regions of the LET spectrum, similar to conventional X-ray or 60Co gamma-ray sources. The device has two operating modes, as a conventional microbeam targeting single cells or subpopulations of cells or as a pseudo broad-beam source allowing for direct comparison with conventional sources. By varying the incident electron energy, the target cells can be selectively exposed to different parts of the energetic electron tracks, including the track ends.

Electrons↗

Current problems and expected improvements in personal neutron dosimetry.

Many technological activities involve the potential for worker exposure to neutrons. The determination of neutron personal dose equivalent is difficult due to a number of factors including the materials and methods used to evaluate the response of personal dosemeters and the quantities for expressing dose equivalent. Nevertheless, recent progress has been made in the development of devices and techniques for the measurement and calibration of neutron personal dosemeters. The quantities and units used to express neutron dose equivalent are being improved and clarified. Therefore, it is expected that a number of remaining difficulties with neutron dosimetry will be mitigated.

Artifacts↗

Calibration measurements and standards for radiation protection dosimetry.

The safe use of ionising radiation for applications in medicine, electric power production and industrial processes requires accurate measurements that are traceable to national standards. Radiological calibration laboratories provide measurements that may be used to determine the calibration coefficients for personal dosemeters and survey meters. The wide range of ionising radiation applications results in the need for a wide range of reference radiation types and intensities to be available in the calibration laboratory. The methods used and the problems encountered while developing reference radiations are discussed.

Calibration↗

CAD, CAM and CAP.

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Biomedical Research↗