Biomedical subjects

John Walter

Publications and source records attributed to John Walter.

3 recordsLinked to original sources

PubMed2005

Obturators for acquired palatal defects.

UNLABELLED: The developing role of the prosthodontist in the head and neck cancer team is discussed and a sequence of care given for patients who will require the restoration by prosthetic means of surgically created palatal defects. Various styles of definitive obturators are described. CLINICAL RELEVANCE: A knowledge of the care of patients with palatal defects is of value to GDPs and to members of the head and neck cancer team.

Dental Prosthesis Design↗

PubMed2004

Swallowed partial dentures.

Swallowed or inhaled partial dentures can present a diagnostic challenge. Three new cases are described, one of them near-fatal because of vascular erosion and haemorrhage. The published work points to the importance of good design and proper maintenance. The key to early recognition is awareness of the hazard by denture-wearers, carers and clinicians.

Deglutition↗

PubMed2003

Three novel hydroxybenzoate saxitoxin analogues isolated from the dinoflagellate Gymnodinium catenatum.

In a recent survey of paralytic shellfish poisoning (PSP) toxins in Gymnodinium catenatum Graham extracts, using LC with postcolumn oxidation and fluorescence detection, three novel saxitoxin analogues were revealed in isolates from several locations, including Australian waters. We have named them as G. catenatum toxins, GC1 (1), GC2 (2), and GC3 (3). The compounds were isolated from a culture of the Australian strain by LC-MS-guided fractionation employing a C18-silica column and hydrophilic interaction chromatography. The unusual structures of these novel compounds were characterized by low- and high-resolution MS, MS/MS, and NMR spectroscopy. GC3 (3) was found to be the 4-hydroxybenzoate ester derivative of decarbamoylsaxitoxin, while GC1 (1) and GC2 (2) are the epimeric 11-hydroxysulfate derivatives of GC3 (3).

Animals↗