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Biomedical subjects

John P Ney

Publications and source records attributed to John P Ney.

6 recordsLinked to original sources
PubMed2006

Sciatic neuropathy following endovascular treatment of a limb vascular malformation.

BACKGROUND: Endovascular therapy for vascular malformations is one of the treatment options for limb vascular malformations. CASE PRESENTATION: A patient with a vascular malformation of the hip developed ipsilateral leg weakness immediately after endovascular embolization and sclerotherapy. Clinical and electrodiagnostic findings later confirmed an incomplete sciatic neuropathy. CONCLUSION: We propose that endovascular treatment compromised the patient's sciatic nerve either through direct neurotoxicity of the sclerosing agent or ischemic injury.

Case Reports↗
PubMed2006

Treatment of chronic low back pain with successive injections of botulinum toxin a over 6 months: a prospective trial of 60 patients.

OBJECTIVES: The aim of this study was to evaluate the effects of two successive neurotoxin treatments for chronic low back pain using multiple pain rating scales in an open-label, prospective study. METHODS: Adult patients with chronic low back pain received multiple paraspinal muscle injections with a maximum dosing of 500 units of botulinum A toxin per session. Those with a beneficial clinical response received a second treatment at 4 months. Pain was assessed by visual analog scale (VAS), modified low back pain questionnaire (OLBPQ), and a clinical low back pain questionnaire (CLBPQ) at baseline, 3 weeks, 2 months, 4 months, and 6 months after the first treatment. RESULTS: Eighteen women and 42 men, ages 21 to 79 years (mean 46.6 years), with low back pain of a mean duration of 9.1 years were included. Significant improvement in back and radicular pain occurred at 3 weeks in 60% and at 2 months in 58% of the cohort. Beneficial clinical response to the first injection predicted response to reinjection in 94%. A significant minority of patients had a sustained beneficial effect from the first injection at 4 (16.6%) and 6 months (8.3%). Two patients had a transient flu-like reaction after the initial treatment. CONCLUSIONS: Botulinum toxin A improves refractory chronic low back pain with a low incidence of side effects. The beneficial clinical response is sustained with a second treatment.

Adult↗
PubMed2006

Post-traumatic shoulder dystonia in an active duty soldier.

Acquired focal dystonia is often precipitated by minor local traumatic injury, resulting in severe pain and disability. An active duty soldier with shoulder dystonia, after a fall, that responded partially to botulinum toxin A is described. Post-traumatic dystonia as a neurological illness is discussed, with emphasis on mechanisms, precipitating causes, differential diagnosis, and treatment implications for battlefield clinicians.

Adult↗