Biomedical subjects

Ji-dong Guo

Publications and source records attributed to Ji-dong Guo.

3 recordsLinked to original sources

PubMed2005

[Vascularized pedicle iliac crest for the repair of bone and soft tissue defect of lower extremity].

OBJECTIVE: To study the role of transplantation of the vascularized pedicle iliac crest for the repair of bone and soft tissue defect of lower extremity. METHODS: The vascularized pedicle iliac crest was designed for the repair of bone and soft tissue defect of lower extremity according to anatomic feature of leg and foot. Skin graft was used for coverage of the iliac flap. RESULTS: Skin survival could demonstrate the survival of the vascularized pedicle iliac crest indirectly one week postoperatively. Skin survived completely in 4 cases and partly in 3 cases. Callus was seen at the transplantation site one month postoperatively, and K-wires were removed 4 months later in the cases of metatarsal defect. The external fixators were removed in the cases of tibia defect 6 to 8 months postoperatively. The functions of lower extremities were restored in 2 to 4 months. The bone and soft tissue defects were repaired, and ultimate function and cosmetic effects were satisfied after the mean follow up of 10 months (ranged from 6 to 15 months). CONCLUSION: Transplantation of the vascularized pedicle iliac crest is an ideal method for the repair of bone and soft tissue defect of lower extremity. The operation can be performed in one stage. The functions and cosmetic effects are better than the traditional methods.

Adult↗

PubMed2004

Using Greedy algorithm: DBSCAN revisited II.

The density-based clustering algorithm presented is different from the classical Density-Based Spatial Clustering of Applications with Noise (DBSCAN) (Ester et al., 1996), and has the following advantages: first, Greedy algorithm substitutes for R(*)-tree (Bechmann et al., 1990) in DBSCAN to index the clustering space so that the clustering time cost is decreased to great extent and I/O memory load is reduced as well; second, the merging condition to approach to arbitrary-shaped clusters is designed carefully so that a single threshold can distinguish correctly all clusters in a large spatial dataset though some density-skewed clusters live in it. Finally, authors investigate a robotic navigation and test two artificial datasets by the proposed algorithm to verify its effectiveness and efficiency.

Algorithms↗

PubMed2002

[The protective effects of melatonin on global cerebral ischemia-reperfusion injury in gerbils].

AIM: To investigate the effects of melatonin (MT) on histology and behavioral tests during global cerebral ischemia-reperfusion in gerbils. METHODS: Global cerebral ischemia was induced by occluding the bilateral common carotid arteries for 10 min in gerbils. Three doses of MT were administrated intraperitoneally 30 min prior to the onset of ischemia. Locomotor activity was measured by using the open field method 3 and 7 days after the ischemic episode. T maze test was carried out 4, 5 and 6 days after ischemia to assess the working memory of gerbils. Neuronal damage was assessed in CA1 pyramidal layer of gerbil hippocampus and evaluated 7 days after ischemia. RESULTS: MT significantly reversed the locomotor activity increases, ameliorated learning and working memory deficit, and reduced the extent of CA1 hippocampal pyramidal cells injury after transient global cerebral ischemia in the Mongolian gerbil. CONCLUSION: MT provides significantly protective effect against both histological and behavioral consequences of global cerebral ischemia-reperfusion injury in gerbils.

Animals↗