Biomedical subjects

Jeong-Man Park

Publications and source records attributed to Jeong-Man Park.

5 recordsLinked to original sources

PubMed2005

Generating function, path integral representation, and equivalence for stochastic exclusive particle systems.

We present the path integral representation of the generating function for classical exclusive particle systems. By introducing hard-core bosonic creation and annihilation operators and appropriate commutation relations, we construct the Fock space structure. Using the state vector, the generating function is defined and the master equation of the system is transformed into the equation for the generating function. Finally, the solution of the linear equation for the generating function is derived in the form of the path integral. Applying the formalism, the equivalence of reaction-diffusion processes of single species and two species is described.

Journal Article↗

PubMed2003

Universality classification of restricted solid-on-solid type surface growth models.

We consider the restricted solid-on-solid (RSOS) type surface growth models and classify them into dynamic universality classes according to their symmetry and conservation law. Four groups of RSOS-type microscopic models--asymmetric (A), asymmetric-conserved (AC), symmetric (S), and symmetric-conserved (SC) groups--are introduced and the corresponding stochastic differential equations (SDEs) are derived. Analyzing these SDEs using dynamic renormalization group theory, we confirm the previous results that A-RSOS, AC-RSOS, and S-RSOS groups belong to the Kardar-Parisi-Zhang class, the Villain-Lai-Das Sarma class, and the Edwards-Wilkinson class, respectively. We also find that SC-RSOS group belongs to a new universality class featuring the conserved-cubic nonlinearity.

Journal Article↗

PubMed2002

Physical model for the gating mechanism of ionic channels.

We propose a physical model for the gating mechanism of ionic channels. First, we investigate the fluctuation-mediated interactions between two proteins imbedded in a cellular membrane and find that the interaction depends on their orientational configuration as well as the distance between them. The orientational dependence of interactions arises from the fact that the noncircular cross-sectional shapes of individual proteins constrain fluctuations of the membrane differently according to their orientational configuration. Then, we apply these interactions to ionic channels composed of four, five, and six proteins. As the gating stimulus creates the changes in the structural shape of proteins composing ionic channels, the orientational configuration of the ionic channels changes due to the free energy minimization, and ionic channels are open or closed according to the conformation thereof.

Biophysical Phenomena↗

PubMed2002

Universality class of the restricted solid-on-solid model with hopping.

We study the restricted solid-on-solid (RSOS) model with finite hopping distance l(0), using both analytical and numerical methods. Analytically, we use the hard-core bosonic field theory developed by the authors [Phys. Rev. E 62, 7642 (2000)] and derive the Villain-Lai-Das Sarma (VLD) equation for the l(0)=infinity case, which corresponds to the conserved RSOS (CRSOS) model and the Kardar-Parisi-Zhang (KPZ) equation for all finite values of l(0). Consequently, we find that the CRSOS model belongs to the VLD universality class and that the RSOS models with any finite hopping distance belong to the KPZ universality class. There is no phase transition at a certain finite hopping distance contrary to the previous result. We confirm the analytic results using the Monte Carlo simulations for several values of the finite hopping distance.

Journal Article↗

PubMed2001

Derivation of continuum stochastic equations for discrete growth models.

We present a formalism to derive the stochastic differential equations (SDEs) for several solid-on-solid growth models. Our formalism begins with a mapping of the microscopic dynamics of growth models onto the particle systems with reactions and diffusion. We then write the master equations for these corresponding particle systems and find the SDEs for the particle densities. Finally, by connecting the particle densities with the growth heights, we derive the SDEs for the height variables. Applying this formalism to discrete growth models, we find the Edwards-Wilkinson equation for the symmetric body-centered solid-on-solid (BCSOS) model, the Kardar-Parisi-Zhang equation for the asymmetric BCSOS model and the generalized restricted solid-on-solid (RSOS) model, and the Villain-Lai-Das Sarma equation for the conserved RSOS model. In addition to the consistent forms of equations for growth models, we also obtain the coefficients associated with the SDEs.

Journal Article↗