Trauma cases from Harborview Medical Center. Airway injury after acute chlorine exposure.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to Jeffrey P Kanne.
Explore the source record for details and available documents.
OBJECTIVE: To describe 2 cases of lipoid pneumonia in Mexican American infants after administration of vegetable- or animal-derived oils and the cultural barriers to diagnosis. Various folk remedies have been documented in the international medical literature that involve the oral or nasal administration of vegetable- or animal-derived oils to children for the treatment of common ailments, including nasal stuffiness, constipation, and colic. Lipoid pneumonia is a known complication of such practices in Mexico, India, Saudi Arabia, and other countries. METHODS: Case reports of 2 Mexican American infants with respiratory distress and interviews with 30 immigrant families of Mexican origin. RESULTS: In both cases, language and cultural barriers resulted in a delayed diagnosis of lipoid pneumonia. Interviews with immigrant families confirmed that oil administration to children is a common traditional therapy in Mexican cultures. CONCLUSIONS: These findings underscore the need for primary care providers to be aware of the traditional practice of oil administration to infants in many cultures, its pathophysiological consequences, the potential cultural barriers to timely diagnosis, and the opportunity to prevent cases of lipoid pneumonia through anticipatory guidance.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
During the 1990s, computed tomography (CT) and magnetic resonance (MR) imaging underwent extensive technological advancement and expanded clinical use in patients with venous thromboembolic disease, particularly with regard to evaluation of the pulmonary vasculature. In many institutions, helical (spiral) CT pulmonary angiography has become the initial imaging study of choice to evaluate patients with suspected pulmonary embolism, supplanting ventilation/perfusion scintigraphy. In addition, CT venography of the pelvis and lower extremities is often incorporated into the CT angiography protocol to identify or exclude concurrent deep venous thrombosis. MR pulmonary angiography and MR venography are second-line diagnostic tools because of their higher cost, limited availability, and other logistical constraints. As the technology improves and becomes more widely available, MR imaging may play a greater role in the evaluation of patients with venous thromboembolic disease.
Pneumoperitoneum outside the setting of recent surgical intervention usually indicates perforation of the gastrointestinal tract. Following radiologic evidence of pneumoperitoneum, surgical exploration of the abdomen may be indicated depending on the nature of the patient's presentation. We present the radiological findings of a healthy young woman who presented with acute onset of abdominal pain and was found to have extensive pneumoperitoneum. No visceral disruption was evident by multidetector CT or by single-contrast barium fluoroscopic evaluation of the upper gastrointestinal tract. Knowledge of benign causes of pneumoperitoneum by the radiologist may avert an unnecessary laparotomy.
Intracranial aneurysms occur in patients with autosomal dominant polycystic kidney disease (ADPKD) approximately five times more often than in the general population, and in the same patient group, subarachnoid hemorrhage from rupture of aneurysms occurs about a decade earlier than in the general population. We present a case of unsuspected ADPKD presenting as spontaneous subarachnoid hemorrhage from a ruptured intracranial aneurysm.
Diffuse pulmonary ossification (DPO) is an uncommon condition that is characterized by metaplastic bone formation in the lung parenchyma. It is usually not diagnosed clinically and may be apparent radiographically only when extensive. However, it is occasionally encountered at autopsy or on pathologic evaluation of surgical specimens. This article will review the clinical, histologic, and radiographic manifestations of DPO, focusing primarily on the chest radiograph and CT findings, both of which may be underappreciated, for even experienced radiologists may confuse DPO with other entities such as metastatic calcification as seen in chronic renal failure or chronic granulomatous disease.
Explore the source record for details and available documents.
A previously healthy 23-year-old man with nonproductive cough and sore throat presented to the hospital a few hours after chlorine gas exposure at a fitness center swimming pool. Initial physical examination and chest radiograph were normal. Thirty-six hours later he developed worsening dyspnea and cough, with development of blood-tinged sputum. Arterial blood gas analysis showed mild hypoxemia and a subsequent chest radiograph demonstrated diffuse tiny nodular opacities. Findings on a thin-section computed tomogram of the chest were consistent with diffuse bronchiolitis. Pulmonary function tests showed a mild obstructive abnormality and he demonstrated substantial bronchodilator response. The patient was treated with oral corticosteroids and an inhaled beta(2) agonist, to which he responded well, with full clinical recovery occurring over 5 months. This manifestation of chlorine gas exposure at a swimming pool is unusual.
INTRODUCTION: Helical computed tomography angiography (CTA) has become an established technique for evaluating atherosclerosis of the cerebrovascular arteries. However, the role of CTA in penetrating and blunt trauma to the carotid and vertebral arteries is not well defined. We conducted a systematic literature review to determine the diagnostic accuracy of CTA for atherosclerotic, penetrating and blunt lesions in the carotid and vertebral arteries. METHODS: We searched MEDLINE and EMBASE databases to identify studies evaluating the diagnostic accuracy of CTA of the carotid and vertebral arteries published between January 1, 1992 and December 31, 2002. Two reviewers independently assessed abstracts and full text to determine study eligibility. Information on methodological quality, imaging technique and diagnostic accuracy was abstracted from all eligible studies by three independent reviewers. We pooled sensitivity and specificity data from diagnostic accuracy studies of high methodological quality. RESULTS: Forty-three articles met the inclusion criteria and were included in the review. Thirty studies examined atherosclerotic disease, two blunt trauma, two penetrating trauma and nine examined patients with other pathology. Pooled data from 15 higher quality studies demonstrated that CTA had a sensitivity of 95% (91-97% CI) for detecting severe (>70%) atherosclerotic stenosis of the carotid artery. The specificity of CTA for severe stenosis was also high 98% (96-99% CI). CTA remained a sensitive technique (95%; 93-97% CI) when the criterion for a positive result is relaxed to moderate or greater (>30%) stenosis. Two studies raised concerns about the use of CTA in the blunt trauma setting, suggesting that CTA may not be sensitive for detecting small intimal injuries, although both of these studies used older technologies for either obtaining or viewing images. Conversely, two penetrating trauma studies concluded that the sensitivity of CTA was high. CONCLUSIONS: Our findings demonstrate that CTA is both a sensitive and specific imaging technique for identifying severe atherosclerotic stenosis and occlusion of the carotid arteries. However, there is currently not enough high quality evidence to accurately estimate the sensitivity and specificity of CTA in the setting of blunt or penetrating trauma.
Explore the source record for details and available documents.
OBJECTIVE: Our purpose was to describe the imaging findings of central pulmonary embolism on unenhanced multidetector CT (MDCT) of the chest. CONCLUSION: Unenhanced MDCT of the chest is often performed for the evaluation of nonspecific chest symptoms. Awareness of the rare finding of a high-attenuation centrally located pulmonary embolism on unenhanced MDCT is important because acute pulmonary embolism may be identified when it is not suspected clinically, and such detection can determine further imaging needs and allow the timely initiation of appropriate therapy.
The placenta is the central support organ for the developing fetus. Recognition of placental variants and insignificant findings is important so as not to suggest an abnormality when one is not present. However, the degree of abnormality, as well as the clinical implications of the findings, must be understood to help guide management of the pregnancy. This article reviews the normal sonographic appearance of the placenta and some anatomic variants, in addition to illustrating various common pathological conditions of the placenta and correlating with gross pathologic and histologic specimens.
OBJECTIVE: The purpose of this article is to describe the imaging findings of acute central pulmonary embolism on computed tomography (CT) densitometry images performed before contrast-enhanced CT pulmonary angiography. METHODS: A retrospective review was conducted of reports from all CT pulmonary angiograms performed at our institution, and cases of acute central pulmonary embolism, defined as those with clot in the main, left, or right pulmonary arteries, were identified. Images of positive studies were reviewed on a picture archiving and communications system (PACS) workstation. RESULTS: A total of 1282 CT pulmonary angiograms were obtained for evaluation of possible acute pulmonary embolism, and 1 combined CT aortogram and pulmonary angiogram was performed for aortic dissection and acute pulmonary embolism. Two hundred fourteen (16.7%) examinations positive for acute pulmonary embolism were identified, 26 (12.1%, 2.0% of total examinations) of which had central clots. Of the 26 patients with central acute pulmonary embolism, 12 (46.1%, 5.6% of all positive studies and 0.9% of all CT pulmonary angiograms) had clots that were visible on the densitometry images. CONCLUSION: Although an uncommon finding, acute central pulmonary embolism can be detected on CT densitometry performed to optimize opacification of the pulmonary arteries for CT pulmonary angiography and may prove useful in selected clinical situations.
Systemic lupus erythematosus (SLE) is an unusually complex autoimmune disease that is encountered in every radiology subspecialty because of its multisystem involvement and the wide age range of affected patients. There are no universally accepted diagnostic imaging criteria for SLE, and in fact, many SLE patients present with systemic findings and laboratory abnormalities and do not require imaging. Nevertheless, radiology plays an ancillary role in the diagnosis and management of this often insidious disease, and knowledge of the spectrum of radiologic findings in SLE and its complications is crucial for proper image interpretation. Imaging is often performed in patients with a known diagnosis of SLE to determine the extent and severity of disease, which depend on the extent of organ involvement, and to monitor complications. In addition, imaging may be important in selected patients with diseases such as pneumonia who present with atypical symptoms due to immunosuppressive therapy.
Eponyms serve as a means of honoring individuals who have made important discoveries and observations. Eponyms are frequently encountered in the field of radiology, particularly in radiology of the digestive tract. However, the use of eponyms may fail to convey a precise meaning or definition and could lead to miscommunication. Moreover, in some instances, more than one individual may have contributed to the discovery or description of a particular anatomic structure or disease, whereas in others, an eponym may have been incorrectly applied initially and propagated for years in the medical literature. Nevertheless, radiologic eponyms are a means of honoring those who have made lasting contributions to the field of radiology, and familiarity with these eponyms is important for proper reporting and accurate communication. In addition, the acquisition of some historical knowledge about those whose names are associated with various structures or pathologic conditions brings some humanity back into the science of medicine.
Eponyms are a means of honoring individuals who have made lasting contributions to medicine. Eponyms are frequently encountered in the field of radiology, especially radiology of the digestive tract. However, the use of eponyms may fail to convey a precise meaning or definition and could result in miscommunication. Furthermore, in some instances, more than one individual may have contributed to the discovery or description of a particular structure or disease, whereas in others, an eponym may have been incorrectly applied and then propagated for years thereafter in the medical literature. Still, eponyms are a means of honoring those who have made important discoveries and observations, and familiarity with these terms is important for proper reporting and accurate communication. Moreover, the acquisition of some historical knowledge about the individuals whose names are associated with various structures or diseases helps restore some humanity to the science of medicine.