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Jean-Louis Pariente

Publications and source records attributed to Jean-Louis Pariente.

23 records · Page 2Linked to original sources
PubMed2004

[The ureteric risk in laparoscopic surgery].

OBJECTIVE: To describe the circumstances of development, diagnostic approach and treatment of iatrogenic ureteric lesions after laparoscopic surgery. MATERIAL AND METHODS: From 1992 to 2003, nine patients with iatrogenic trauma of the ureter after laparoscopic surgery were managed by our team. RESULTS: The time to diagnosis ranged from 0 to 640 days. These injuries were related to gynaecological surgery in 56% of cases, gastrointestinal surgery in 22% of cases, vascular surgery in 11% of cases, and spinal surgery in 11% of cases. The two lesions identified intraoperatively were treated immediately with success. In the case of lesions identified secondarily, first-line endourological treatment was performed in 57% of cases with a good result without reoperation in only 25% of cases. Three patients required reoperation with 66% of satisfactory results and two patients were treated by nephrectomy. CONCLUSION: Intraoperative difficulties and limited experience of laparoscopic surgery are the factors most frequently identified in iatrogenic ureteric lesions. The time to diagnosis has a considerable impact on the modalities and results of management.

Adult↗
PubMed2004

[Urothelial tumors].

Explore the source record for details and available documents.

Carcinoma, Transitional Cell↗
PubMed2003

[Evaluation of the results of TVT in a series of 29 major sphincter incompetence].

OBJECTIVE: The objective of this study was to evaluate the results of TVT in patients with stress urinary incontinence due to major sphincter incompetence and a closing pressure less than 20 cm H2O. MATERIALS AND METHODS: From March 1998 to March 2001, 29 patients with a mean age of 69 years (range: 36-92) with incontinence due to major sphincter incompetence were treated by this technique. The patients were reviewed at 3 months and then annually. RESULTS: The mean follow-up is 30 months (range: 12-48). 25 patients (87%) obtained a good result, including 16 (55%) with perfect continence, while 9 (32%) were improved and 4 (13%) were considered to be failures. CONCLUSION: TVT constitutes a justified treatment for major sphincter incompetence compared to suburethral slings and in patients who would have been candidates for artificial sphincter implantation before the arrival of TVT. This minimally invasive surgery considerably improves the patient's quality of life. The existence of moderate residual urine or dysuria after insertion of TVT does not alter the functional result or the upper urinary tract.

Adult↗
PubMed2002

In vitro biocompatibility evaluation of naturally derived and synthetic biomaterials using normal human bladder smooth muscle cells.

PURPOSE: Tissue engineering of the urinary tract often requires the use of various biomaterials. Adequate biomaterial biocompatibility is necessary for successful urinary reconstruction. In this study using a primary normal human bladder smooth muscle cell culture system we evaluated the in vitro biocompatibility of a number of naturally derived biomaterials, including bladder submucosa, small intestinal submucosa, collagen and alginate, and polymeric biomaterials, including polyglycolic acid, poly(L-lactic acid) and poly(lactic-co-glycolic acid, which have been used for urinary reconstruction experimentally or clinically. MATERIALS AND METHODS: To determine the cytotoxic and bioactive effects of bladder submucosa, small intestinal submucosa, collagen, alginate, polyglycolic acid, poly(L-lactic acid) and poly(lactic-co-glycolic acid) we measured cell viability, metabolic activity, apoptotic properties and DNA synthesis activity with 4 types of assays, namely Neutral Red (Sigma Chemical Co., St. Louis, Missouri), 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (Sigma Chemical Co.), apoptotic activity and tritiated thymidine incorporation (Dupont NEN, Boston, Massachusetts) assays. Normal human bladder smooth muscle cells were cultured with the extracts of the biomaterials or cultured in direct contact with the biomaterials. RESULTS: All naturally derived and synthetic biomaterials tested in this study except alginate exhibited nontoxic and bioactive effects on human bladder smooth muscle cells (HBSMCs) in vitro, as indicated by the 4 types of biocompatibility assays using the extract and direct contact methods. Cell viability, apoptotic properties, metabolic activity and DNA synthesis activity of HBSMCs cultured with the extracts of the biomaterials or cultured in direct contact with the biomaterials were not significantly different from those of negative controls (fresh medium with no extracts or tissue culture plates without biomaterials). CONCLUSIONS: All naturally derived and synthetic biomaterials tested in this study except alginate exhibited nontoxic and bioactive effects on HBSMCs in vitro. This normal primary human bladder smooth muscle cell culture model is suitable for in vitro biocompatibility assessment. It provides information on cell-biomaterial interactions and on the ability of biomaterials to support bioactive cell functions.

Biocompatible Materials↗