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Biomedical subjects

Jaya Agrawal

Publications and source records attributed to Jaya Agrawal.

At least 19 recordsLinked to original sources
PubMed2006

Incomplete capsular bag distension syndrome after neodymium:YAG capsulotomy.

We report a 60-year-old man with incomplete capsular bag distension syndrome 2 years after neodymium:YAG (Nd:YAG) laser capsulotomy for capsule opacification, which developed from extracapsular cataract extraction with intraocular lens (IOL) implantation performed 4 years before presentation to our clinic. The patient reported floaters of 15 days duration. Slitlamp examination showed shallowing of the inferior and medial anterior chamber. Dilated pupil examination showed a peripheral capsular bag inferiorly and medially behind the IOL. The bag was distended and filled with turbid fluid. The central and superior capsule was absent as a result of the previous Nd:YAG treatment. The IOL lie over the anterior capsule, and peripheral capsule leaves' edges were adhered. An Nd:YAG laser puncture of the incomplete capsular bag resolved the condition.

Cataract Extraction↗
PubMed2005

Colon cancer screening strategies.

PURPOSE OF REVIEW: Screening and prevention of colorectal cancer is a public health priority. Fecal occult blood testing is a popular screening test because of its simplicity, noninvasiveness, and demonstrated mortality benefit. At the same time, guaiac tests suffer from poor sensitivity, limited ability to detect early lesions, the need for annual testing, low population compliance, and high costs of follow-up for false-positive tests. These limitations have sparked many innovations in stool testing. RECENT FINDINGS: Recent studies suggest that both community intervention and physician awareness are needed to improve patient compliance with fecal occult blood testing and colorectal cancer screening in general. Despite the low costs of the guaiac test, the high false positives and high false negatives of fecal occult blood testing lead to high costs and low cost-effectiveness when compared with endoscopic techniques. Fecal DNA testing promises to improve the performance characteristics of stool testing. Small trials of multitarget assays demonstrate a sensitivity for colorectal cancer of 62 to 91% and a sensitivity for adenomas of 26 to 73%. The specificity of these assays is high, ranging from 93 to 100%. The major drawback of fecal DNA testing, compared with other fecal colorectal cancer screening tests, is the cost. SUMMARY: Preliminary data on fecal DNA tests show better performance characteristics than fecal occult blood tests. In their current form, however, it is not clear that the added sensitivity merits the additional cost. These tests must be studied in larger cohorts of asymptomatic patients before adequate comparison can be made to established colorectal cancer screening techniques.

Biomarkers, Tumor↗
PubMed2004

Orbital cysticercosis-associated scleral indentation presenting with pseudo-retinal detachment.

PURPOSE: To report a clinical picture similar to retinal detachment caused by orbital myocysticercosis-associated scleral indentation. DESIGN: Interventional case series. METHODS: Of the 49 cases of orbital myocysticercosis, four eyes of four patients had pseudoretinal detachment presentations that are detailed. RESULTS: Of the four patients with pseudoretinal detachment, three were found to have orbital myocysticerci in lateral and one in inferior recti muscles, mechanically indenting the eyeball, causing scleral indentation, evidenced by ultrasonography or computed tomography. Associated signs of myocysticercosis were orbital inflammation, restricted ocular motility or proptosis. In 2 to 10 days, the cysts traveled forward and came to lie in a sub-Tenon position. Three cysts were removed surgically and one extruded spontaneously. CONCLUSIONS: Patients presenting with a clinical picture similar to retinal detachment in the presence of symptoms and signs of orbital cysticercosis, with a history of exposure to an endemic area, should be considered to have orbital myocysticerci causing scleral indentation.

Adolescent↗
PubMed2004

Vitrectomy as a treatment for elevated intraocular pressure following intravitreal injection of triamcinolone acetonide.

PURPOSE: To report control of intravitreal triamcinolone acetonide-induced elevated intraocular pressure (IOP) by vitrectomy-assisted corticosteroid removal. DESIGN: Interventional case series. METHODS: Of the 26 eyes that had intravitreal injection of triamcinolone acetonide for various causes, 11 eyes (42.5%) developed elevated IOP. In nine eyes IOP was controlled by antiglaucoma medication. Two eyes of two patients developed uncontrolled IOP despite maximal antiglaucoma medication. These eyes underwent vitrectomy and removal of triamcinolone acetonide. RESULTS: IOP returned to normal in 3 weeks and 1 week, respectively, after vitrectomy. CONCLUSIONS: Elevated IOP associated with intravitreal injection of triamcinolone acetonide that is not controlled by maximal antiglaucoma medication can be effectively treated by vitrectomy-assisted removal of triamcinolone acetonide.

Drainage↗
PubMed2003

Conjunctival ulceration following triamcinolone injection.

PURPOSE: To report conjunctival ulceration as a complication of periocular triamcinolone acetonide injection. Interventional case series. METHODS: Conjunctival ulceration was found in three patients who had anterior subtenon's or subconjunctival deposition of triamcinolone. Cultures from the ulcer edges were negative. RESULTS: Most of the triamcinolone extruded, and the conjunctival ulcers healed with minimal scarring. CONCLUSIONS: Conjunctival ulceration was a potential complication of periocular triamcinolone injection in three patients who had anterior subtenon's or subconjunctival deposition of the corticosteroid.

Adult↗
PubMed2002

Silicone sleeve of extrusion cannula as an intraocular foreign body.

An unusual intraocular foreign body--the silicone sleeve of a soft-tipped extrusion cannula left behind accidentally in the vitreous cavity following a vitreoretinal surgical procedure for complex retinal detachment--is reported. The silicone sleeve remained within the eye for a year without causing any problem.

Adult↗