Designing drugs.
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Antimetabolites, Antineoplastic↗
Biomedical subjects
Janet Yagoda Shagam
Publications and source records attributed to Janet Yagoda Shagam.
Genetics, genomics and molecular medicine.
Genomics and the Human Genome Project are creating important changes in medical care and radiologic practice. Readers of this article will: Recall that deoxyribonucleic acid (DNA) is the information-containing molecule. Understand the relationship between DNA and protein synthesis. Learn that changes in DNA-encoded proteins produce pathogenesis. Distinguish between genomics and proteomics. Describe the Human Genome Project. Define and give examples of molecular medicine and its imaging applications. Discuss how genomics, genetic engineering and the Human Genome Project may influence radiologic practice.
Genetic Engineering↗
Bone densitometry: an update.
After completing this article on osteoporosis and bone densitometry, readers will be able to: Summarize the economic and psychosocial effects of osteoporosis. Differentiate between primary and secondary causes of osteoporosis. List the risk factors associated with osteoporosis and osteoporotic bone fractures. Describe techniques for preventing osteoporosis. Compare and contrast pharmaceutical agents used to treat osteoporosis. Discuss techniques used to measure bone mineral density, including DXA, pDXA and ultrasound. Know how to prepare and position a patient for a bone density scan and how to minimize radiation exposure to the patient, the technologist and others.
Absorptiometry, Photon↗
Readers dispute hepatitis facts.
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Antiviral Agents↗
Urinary incontinence and ultrasound imaging.
After completing this overview of incontinence in women, readers will be able to: Explain why urinary incontinence is an under-reported condition. Describe the urinary tract. Identify risk factors for urinary incontinence. List and describe different classifications of urinary incontinence. Explain the roles of the medical history, physical examination and urinalysis in helping clinicians diagnose and treat urinary incontinence. Describe urinary incontinence diagnostic procedures. Explain the importance of ultrasound in urinary incontinence diagnosis and treatment. Discuss the potential role of ultrasound as a urinary incontinence screening tool. Classify and categorize urinary incontinence treatments from least to most invasive.
Female↗
Medical imaging and CNS infections.
West Nile virus, Creutzfeldt-Jakob disease and new-variant CJD are emergent infectious diseases that affect the brain. Although incidence of these infections is low compared with other CNS diseases such as viral or bacterial meningitis, the reasons for their emergence are complex. Scientists believe that unique combinations of genetic, environmental and social factors have caused these rare pathogens to become more common within human populations. Because the causes of brain infections are difficult to diagnose and treat, medical imaging is an important screening, diagnostic and monitoring tool. By supplying pathogen-specific visual clues, medical imaging studies provide the evidence that allow clinicians to begin life-saving supportive care and treatment.
Central Nervous System Infections↗
Pelvic organ prolapse.
Pelvic organ prolapse, a condition in which the ligaments and muscles that suspend the vagina within the pelvic cavity weaken or break, is a frequent cause of urinary and fecal incontinence. Stigma, embarrassment and the belief that pelvic organ prolapse is a natural part of aging prevents many women from seeking treatment. Medical imaging modalities such as defecography, dynamic magnetic resonance imaging and ultrasound help health care providers make effective treatment decisions.
Diagnostic Imaging↗