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Biomedical subjects

Jamshid Ahmadi

Publications and source records attributed to Jamshid Ahmadi.

25 records · Page 2Linked to original sources
PubMed2002

Buprenorphine maintenance treatment of heroin dependence: the first experience from Iran.

The aim of this study was to assess the efficacy of 1-, 2-, and 4-mg-per-day sublingual doses of buprenorphine in the maintenance treatment of heroin-dependent patients over a 17-week treatment period. Subjects were randomized to three dosage groups. Participants consisted of 105 heroin addicts (102 men and 3 women) who met the DSM-IV criteria for opioid dependence and were seeking treatment. Subjects received buprenorphine at a dose of 1, 2, or 4 mg per day and were treated in an urban outpatient clinic, including a weekly 1-hour individual counseling session. Days retained in treatment were measured. Overall, 49 patients (46.7%) completed the 17-week study. Completion rates by dosage group were 34.3% for the 1 mg dose group, 42.9% for the 2 mg dose group, and 62.9% for the 4 mg dose group. Retention in the 4 mg dose group was significantly better than in the 1 mg dose group (P = .017). None of the other comparisons was significant. The results support the efficacy and safety of buprenorphine for outpatient treatment of heroin dependence and seem to indicate that the highest dose (4 mg) of buprenorphine was the best of the three doses for Iranian heroin addicts to increase their retention in treatment.

Adolescent↗
PubMed2002

Buprenorphine treatment of opium-dependent outpatients seeking treatment in Iran.

The goal of this study was to evaluate the efficacy of 1-, 3-, and 8-mg per day doses of buprenorphine in the maintenance treatment of opium-dependent patients over a 6-month treatment period. Participants were 513 opium-dependent individuals who were seeking treatment in an urban outpatient clinic, offering a 1-hr weekly individual counseling session. Overall, 305 patients (59.5%) completed the 6-month study. Completion rates by dosage group were 33.9% for the 1-mg dose group, 64.3% for the 3-mg dose group, and 80.1% for the 8-mg dose group-each significantly different from the other two groups. The results support the efficacy and safety of buprenorphine for outpatient treatment of opium dependence and seem to indicate that the highest dose (8 mg) of buprenorphine was the best of the three doses for Iranian opium-dependent patients to increase their retention in treatment.

Adult↗
PubMed2002

Various types of exercise and scores on the Beck Depression Inventory.

This study investigated scores on depression of students in sports. 311 (ns = 60, 100, 100, 40, 11) female athletic candidates were selected randomly and administered the Beck Depression Inventory. Initially, 60 persons who had gone through a body-building course for less than 1 month took the inventory and again after 4 wk. The mean score difference was -3.5. This decline in mean depression score after 4 wk. of exercise was significant. In the next step, 100 women new to body building and 100 women who had completed 2 mo. body building were compared. Their mean scores were 13.3 for newcomers and 10.2 for the 2-mo. group, a significant difference. Finally, 40 female athletes who had swum for less than 1 mo. were compared with professional swimmers from the Fars province. Their mean depression scores were 10.5 and 6.5, respectively. This difference was also significant. We concluded that exercising is associated with lower mean scores on the Beck Depression Inventory.

Adolescent↗
PubMedDate not supplied

Outcome predictors in cocaine dependence treatment trials.

Finding the predictors of outcome in outpatient cocaine dependence treatment trials may be useful for the development of both psychosocial as well as pharmacological treatments for cocaine dependence. Among the most powerful predictors of response to psychosocial treatment are cocaine withdrawal symptom severity and the results of a urine drug screen (UDS) collected at study entry. The present trial seeks to extend these findings by examining outcome predictors in a large number of subjects participating in a series of outpatient cocaine pharmacotherapy trials while selecting three separate criteria to define successful outcome. The ability of several baseline variables were tested to predict treatment outcome in a series of cocaine medication trials that included 402 cocaine-dependent subjects. Predictor variables included results from the baseline Addiction Severity Index (ASI), initial UDS results, and cocaine withdrawal symptom severity at treatment entry, as measured by scores on the Cocaine Selective Severity Assessment (CSSA). Outcome measures included UDS results obtained during the trials and results from the ASI gathered at the end of the trials. Baseline variables that most consistently predicted treatment outcome were the initial UDS results and initial CSSA scores. These findings indicate that baseline UDS results and CSSA scores are powerful predictors of outcome and should be used as stratifying variables in outpatient cocaine medication trials.

Adult↗
PubMedDate not supplied

Substance use among Iranian nephrologic patients.

AIMS: This study assessed the prevalence of substance use among Iranian patients with nephrologic disease (chronic renal failure) who were admitted in different nephrologic wards at Shiraz general hospitals. DESIGN: Cross-sectional survey using structured interview and also using DSM-IV criteria for substance dependency. SETTING: General hospitals in Shiraz city (patients with nephrologic disease admitted in different nephrologic wards). PARTICIPANTS: 64 (32 men and 32 women) patients selected randomly. FINDINGS: Data were gathered by a structured interview from 64 patients admitted in nephrologic wards of general hospitals in 2001. The mean age was 49.39 years (SD = 19.62) ranging from 18 to 80 years. 26 (40.6%) of the subjects (65.6% of the men and 15.6% of the women) reported the use of substance(s) once or more in their lives. The majority, 23 (35.9%) used tobacco, 9 (14.1%) used opium and 2 (3.1%) used alcohol. None had used cannabis, heroin, cocaine or LSD. 20 (31.3%) of the subjects (50% of the men and 12.5% of the women) were currently substance dependent, using DSM-IV criteria. The majority, 18 (28.1%) were nicotine dependent, and 6 (9.4%) were opium dependent. There was a nonsignificant relationship between income or occupation or education and prevalence of substance use. The reported reasons for initial use of substance(s), in order of frequency, were enjoyment, modeling and release of tension, and also for current users were, habit, enjoyment and need. CONCLUSIONS: Substance use especially cigarettes, opium and alcohol was found to be high among patients. There was no report of cannabis, heroin, cocaine or LSD use. Cultural attitudes toward substance use were found to affect the type and amount of use. These findings can be considered when planning preventive or therapeutic programs.

Adolescent↗