Search PubMed⌕ Search

Biomedical subjects

Jackie S McGhie

Publications and source records attributed to Jackie S McGhie.

11 recordsLinked to original sources
PubMed2006

True mitral annulus diameter is underestimated by two-dimensional echocardiography as evidenced by real-time three-dimensional echocardiography and magnetic resonance imaging.

BACKGROUND: Mitral annulus assessment is of great importance for the diagnosis and treatment of mitral valve disease. The present study sought to assess the value of real-time three-dimensional echocardiography for the assessment of true mitral annulus diameter (MAD). METHODS: One hundred and fifty patients (mean age 38 +/- 18 years) with adequate two-dimensional (2D) echocardiographic image quality underwent assessment of MAD(2D) and MAD(3D) (with real-time three-dimensional echocardiography). In a subgroup of 30 patients true MAD was validated with magnetic resonance imaging (MRI). RESULTS: There was a good interobserver agreement for MAD(2D) (mean difference = -0.25 +/- 2.90 mm, agreement: -3.16, 2.66) and MAD(3D) (mean difference = 0.29 +/- 2.03, agreement = -1.74, 2.32). Measurements of MAD(2D) and MAD(3D) were well correlated (R = 0.81, P < 0.0001). However, MAD(3D) was significantly larger than MAD(2D) (3.7 +/- 0.9 vs. 3.3 +/- 0.8 cm, P < 0.0001). In the subgroup of 30 patients with MRI validation, MAD(3D) and MAD(MRI) were significantly larger than MAD(2D) (3.3 +/- 0.5 and 3.4 +/- 0.5 cm vs. 2.9 +/- 0.4 cm, both P < 0.001). There was no significant difference between MAD(MRI) and MAD(3D). CONCLUSION: MAD(3D) can be reliably measured and is superior to MAD(2D) in the assessment of true mitral annular size.

Adult↗
PubMed2006

Assessment of pulmonary valve and right ventricular outflow tract with real-time three-dimensional echocardiography.

AIM: Assessment of pulmonary valve (PV) and right ventricular outflow tract (RVOT) using real-time 3-dimensional echocardiography (RT3DE). METHODS: Two-dimensional echocardiography (2DE) and RT3DE were performed in 50 patients with congenital heart disease (mean age 32 +/- 9.5 years, 60% female). Measurements were obtained at parasternal views: short axis (PSAX) at aortic valve level and long axis (PLAX) with superior tilting. RT3DE visualization was evaluated by 4-point score (1: not visualized, 2: inadequate, 3: sufficient, and 4: excellent). Diameters of PV annulus (PVAD), and RVOT (RVOTD) were measured by both 2DE and RT3DE, while areas (PVAA) and (RVOTA) by RT3DE only. RESULTS: By RT3DE, PV was visualized sufficiently in 68% and RVOT excellently in 40%. PVAD and PVAA were measured in 88%. RVOTD and PVAD by 2DE at PLAX were significantly higher than PSAX (P < 0.0001) and lower than that by RT3DE (P < 0.001). CONCLUSION: RT3DE helps in RVOT and PV assessment adding more details supplemental to 2DE.

Adult↗
PubMed2006

Evaluation of pericardial hydatid cysts by different echocardiographic imaging modalities.

Cardiac hydatid disease or echinococcosis is a rare complication of Echinococcus granulosus infection. Traditionally, the diagnosis is made with two-dimensional transthoracic echocardiography. This case report shows the complementary function of the different echo modalities (two-dimensional, three-dimensional, and contrast echocardiography) and MRI in the evaluation of pericardial hydatid cyst.

Adult↗
PubMed2006

Real-time transthoracic three-dimensional echocardiographic assessment of left ventricular volume and ejection fraction in congenital heart disease.

OBJECTIVE: The purpose of this study was to assess the (1) feasibility of real-time three-dimensional echocardiography (RT-3DE) data acquisition and (2) volumes and function of the abnormal left ventricle (LV) in adult patients with congenital heart disease (CHD), compared with magnetic resonance imaging (MRI) data. METHODS: Thirty-two patients (59% were male) with CHD were evaluated on the same day by MRI and RT-3DE. Acquisition of RT-3DE data sets was feasible in 29 of the 32 patients (91%). The time of 3D data acquisition was 4 +/- 2 minutes, and LV analysis was 17 +/- 5 minutes per patient for manual border tracing. RESULTS: A good correlation was observed between RT-3DE with manual border detection and MRI for LV end-diastolic volume (r = 0.97), LV end-systolic volume (r = 0.98), and LV ejection fraction (r = 0.94). CONCLUSION: RT-3DE is feasible for volumetric analysis of the abnormal LV allowing accurate determination of LV volume and ejection fraction compared with MRI in adult patients with CHD.

Adult↗
PubMed2006

Feasibility and accuracy of real-time 3-dimensional echocardiographic assessment of ventricular septal defects.

The aim of this study was to evaluate feasibility, accuracy, and clinical applicability of real-time (RT) transthoracic 3-dimensional (3D) echocardiography (3DE) in the determination of the position, size, and shape of a ventricular septal defect (VSD). In all, 34 patients (age: 2 months-46 years), who were scheduled for surgical closure of a VSD, were enrolled in the study. VSD localization, shape, and dimensions were assessed and compared with measurements performed by the surgeon. Acquisition of RT-3DE datasets was feasible in 30 of 34 (88%) patients. Duration of 3D data acquisition was 6 +/- 2 minutes. Reconstruction time was 23 +/- 16 minutes. Localization and number of VSD were determined correctly by RT-3DE in all patients. There was a good correlation for VSD measurements between RT-3DE and operation (r = 0.95). RT-3DE allows accurate determination of VSD size, shape, and location. The short acquisition time and acceptable reconstruction time make this technique clinically applicable.

Adult↗
PubMed2006

Real-time 3-dimensional echocardiographic evaluation of aortic dissection.

Prompt and correct diagnosis is the cornerstone of effective treatment of aortic (Ao) dissection. Recent studies have demonstrated the usefulness of newly developed imaging modalities for diagnosis of Ao dissection (digital subtraction arteriography, computed tomography, magnetic resonance imaging, and transoesophageal echocardiography). The aim of this study was to demonstrate the clinical usefulness of real-time 3-dimensional echocardiography for the spatial assessment of the Ao tract. Our case suggested that real-time 3-dimensional echocardiography is a valuable method for real-time noninvasive spatial evaluation of dissection of the Ao tract.

Adult↗
PubMed2006

Characterization of atrial septal defect assessed by real-time 3-dimensional echocardiography.

OBJECTIVE: The aim of this study was to describe a quantitative evaluation by real-time 3-dimensional (3D) echocardiography (RT-3DE) of atrial septal defect (ASD) and atrial septum that is important for patient selection for transcatheter closure, and to assess the reliability of RT-3DE findings compared with operation. METHODS: Forty-five patients, who were scheduled for surgical or transcatheter closure of an ASD, were included in the study. RESULTS: In 43 patients (96%), 3D reconstructions allowed optimal imaging of the ASD. The correlations between the ASD maximal diameter by RT-3DE and operation or balloon sizing were excellent (r > 0.95). All surrounding rims of the atrial septum could be assessed on 3D reconstruction; except for the aortic rim, a cross-sectional reconstruction was created mimicking the transesophageal echocardiographic cross section (r > 0.92). CONCLUSION: RT-3DE allows accurate determination of ASD location, ASD size, and surrounding tissue of the atrial septum, and might replace transesophageal echocardiography for patient selection for surgical or transcatheter closure.

Child, Preschool↗
PubMed2005

Dynamic 3D echocardiography in virtual reality.

BACKGROUND: This pilot study was performed to evaluate whether virtual reality is applicable for three-dimensional echocardiography and if three-dimensional echocardiographic 'holograms' have the potential to become a clinically useful tool. METHODS: Three-dimensional echocardiographic data sets from 2 normal subjects and from 4 patients with a mitral valve pathological condition were included in the study. The three-dimensional data sets were acquired with the Philips Sonos 7500 echo-system and transferred to the BARCO (Barco N.V., Kortrijk, Belgium) I-space. Ten independent observers assessed the 6 three-dimensional data sets with and without mitral valve pathology. After 10 minutes' instruction in the I-Space, all of the observers could use the virtual pointer that is necessary to create cut planes in the hologram. RESULTS: The 10 independent observers correctly assessed the normal and pathological mitral valve in the holograms (analysis time approximately 10 minutes). CONCLUSION: this report shows that dynamic holographic imaging of three-dimensional echocardiographic data is feasible. However, the applicability and use-fullness of this technology in clinical practice is still limited.

Computer Graphics↗
PubMed2005

Surgical validation of real-time transthoracic 3D echocardiographic assessment of atrioventricular septal defects.

BACKGROUND: The purpose of this study was to evaluate the accuracy of AV valve morphology assessed by real-time transthoracic 3D echocardiography (RT-3DE) compared to surgical findings and to assess whether RT-3DE is applicable in clinical practice. METHODS: Between June 2004 to May 2005, 19 patients with an atrioventricular septal defect (AVSD) undergoing surgical treatment at our institution were enrolled in the study. RT-3DE was performed with Philips Sonos 7500 echo-system and off-line analysis with TomTec Echoview software. The AVSD was assessed for the morphology of AV valve, with particular interest to the superior and inferior bridging leaflets. 3D data were compared with measurements and descriptions acquired during the surgical procedure. RESULTS: Acquisition of RT-3DE datasets was feasible in all patients. Of the 19 patients, there were 11 infants (age <1 year). The duration of 3D data acquisition was 12+/-3 min for patients above 1 year and 4+/-2 for infants. Reconstruction time was 22+/-8 min. In all patients the AV valve orifice and RT-3DE observations of the superior and inferior bridging leaflets were all correctly identified by RT-3DE compared with the surgical findings. CONCLUSION: Real-time transthoracic 3D echocardiography provides accurate assessment of AVSDs and correctly depicts the AV valve morphology. After a short learning curve, RT-3DE is easily applicable during daily clinical practice.

Adolescent↗
PubMed2005

Comparison of real-time three-dimensional echocardiography to magnetic resonance imaging for assessment of left ventricular mass.

This is the first study to assess the feasibility and accuracy of real-time 3-dimensional echocardiography (RT-3DE) for the measurements of left ventricular (LV) mass in patients with congenital heart disease (CHD) compared with magnetic resonance imaging (MRI). Twenty patients (60% men) with CHD were evaluated by MRI and RT-3DE on the same day. Their mean age was 29 +/- 8 years (range 19 to 49). RT-3DE was performed with a Philips Sonos 7500 echocardiographic system and LV mass analyses with the assistance of TomTec software. The results for LV mass obtained by manual tracing were compared with Signa 1.5-T MRI data. The acquisition of RT-3DE data sets was feasible in all 20 patients. Nine patients (45%) had good, 5 patients (25%) moderate, and 6 patients (30%) poor image quality of the 3-dimensional data set. The time of 3-dimensional data acquisition was 4 +/- 2 minutes. Off-line image processing and tracing required approximately 11 +/- 3 minutes. A very good correlation was observed between RT-3DE data with sufficient image quality and MRI (r = 0.98, y = 0.96x + 4.1, SEE 9.8 g), with a mean difference of 2.0 +/- 20 g. Interobserver agreement was excellent (r = 0.99, y = 0.97x + 3.81), with a mean difference of -1 +/- 11 g. In conclusion, the assessment of LV mass from RT-3DE data is feasible in patients with CHD. The mass of an abnormally shaped left ventricle can be determined with high accuracy and low interobserver variability in patients with good or moderate echocardiographic image quality.

Adult↗