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Biomedical subjects

Jack E Garon

Publications and source records attributed to Jack E Garon.

6 recordsLinked to original sources

Con: Licensure unnecessary in the clinical laboratory.

Those who argue in favor of licensure for clinical laboratory scientists have their priorities in order, but fail to recognize the realities that would ensue were national licensure to be instituted. Higher health-care costs, elimination of rural facilities, and licensure board fraud are all unintended, yet dangerous, consequences that could occur. In his argument against national licensure, laboratory director Jack Garon summarizes some of the most salient research done regarding licensure and presents his case why it is unnecessary in the clinical laboratory.

Attitude of Health Personnel↗

Metastatic pure small-cell carcinoma of prostate.

Extrapulmonary small-cell carcinoma arising in the prostate gland has been described in several case series and case reports. However, pure small-cell carcinoma of the prostate is rare, and there are only a few reports in literature describing the clinical features and management of this neoplasm. These tumors are highly aggressive and commonly manifest with visceral metastasis at the time of diagnosis. We report a case of metastatic pure prostatic small-cell carcinoma and an associated paraneoplastic polyneuropathy.

Adenocarcinoma↗

Recent advances in parathyroid disease and parathyroid hormone assays.

Parathyroid hormone (PTH) regulates extracellular calcium. The physiology and pathology of PTH and the many circulating fragments of PTH are reviewed. Various PTH assays have been used, leading to the now standard intact PTH (iPTH). The recently discovered 7-84 fragment may have profound implications in PTH measurement and management, particularly in renal-failure patients. Newer assays measuring true PTH, exclusive of this fragment, are appearing on the market and may have use in monitoring calcitriol analogue therapy and other settings. Rapid PTH assays have application as intraoperative measures of success during excision of parathyroid adenomas.

Calcium↗

Facilitating meetings.

Facilitating is an alternative style of running meetings. It is collaborative and goal-oriented and is especially useful when creative problem solving or group buy-in is important. Facilitators must master five skills: goal orientation, using ground rules, listening, problem solving, and decisionmaking. This article explains how to successfully master those skills.

Communication↗

Monitoring low molecular weight heparins.

Low molecular weight heparin (LMWH) is used in the treatment of various thrombotic disorders. The clinical indications, pharmacology, and complications of therapy are reviewed. The indications for the need for monitoring include renal failure, obesity, pregnancy, and pediatric use. Monitoring focuses on the anti-Xa properties of LMWH. The two major assay types, chronometric (clotting) and chromogenic (amidolytic), are reviewed and compared.

Anticoagulants↗

Patient safety and the preanalytic phase of testing.

The preanalytic phase of testing includes a variety of procedural steps and variables that affect the patient and the test results. During the preanalytic phase, the patient may be directly harmed or injured. Failures of technique during the preanalytic phase lead to incorrect laboratory results, which threaten the patient's health. This article highlights key problems in the preanalytic phase and offers plans to reduce the problems based on a review of the literature. The key problem areas include: order entry, patient identification, phlebotomy-induced suffering and injury, medical vampirism, and dangerously inaccurate test results caused by failures in preanalytic technique.

Child↗