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Biomedical subjects

J Y Paton

Publications and source records attributed to J Y Paton.

59 records · Page 4Linked to original sources
PubMed1985

The analytical sensitivity of Tc99m radionuclide 'milk' scanning in the detection of gastro-oesophageal reflux.

The analytical sensitivity of radionuclide 'milk' scans for detecting gastro-oesophageal reflux (GOR) has been assessed using an in vitro simulation test. Five factors were found to affect the ability to detect simulated reflux: isotope concentration, absolute gamma camera sensitivity, absorber thickness overlying the 'oesophagus' and volume and duration of reflux. We found that a critical volume-duration product must be exceeded for reflux to be detected. Radionuclide milk scanning appears to be much less sensitive in detecting transient events like GOR than might be expected from previously reported static simulation studies.

Child↗
PubMed1985

Sandifer syndrome: an overlooked diagnosis?

Three retarded children are described who had marked irritability and abnormal movements of the body and contortions of the neck. These movements were diagnosed as epilepsy and the children were treated with numerous anticonvulsants, without success. Subsequently severe gastro-oesophageal reflux was diagnosed, and treatment of the reflux completely eliminated the abnormal movements. Sandifer syndrome was diagnosed, consisting of abnormal body-movements and contortions of the neck, associated with gastro-oesophageal reflux. Suggestions are made to enable early diagnosis of this syndrome.

Asphyxia Neonatorum↗