[The manufacture and efficiency test of the supplimental oxygen equipment for individuals working at high altitude (author's transl)].
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Altitude↗
Biomedical subjects
J X Li
Publications and source records attributed to J X Li.
[Influence of high altitude environment on heart (author's transl)].
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Altitude↗
[The influence of various altitudes and different intensity of labour on the electrical activity of the heart (author's transl)].
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Adolescent↗
[The dynamic observation of electrocardiograms at varios altitudes on the workers of a certain unit (author's transl)].
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Adolescent↗
[The effect of intermittent breathing of oxygen produced by supplemental oxygen equipment (SOE) upon the treatment of chronic altitude hypoxic symptoms (author's transl)].
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Adult↗
O6-methylguanine-DNA methyltransferase and human cancer chemotherapy.
Two kinds of human tumor cell strains having different activity of O6-methylguanine-DNA methyltransferase (O6-MT) were transplanted into nude mice. Mice were then injected intraperitoneally (i.p.) with the bifunctional agent 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride(ACNU). The tumors with low O6-MT activity were quickly suppressed or cured. This result suggests that some tumors, if determined to have low O6-MT activity, might be cured if the host is treated with ACNU. This observation may open a new approach to experimental cancer chemotherapy. Treatment with ACNU of experimental animals bearing HeLaMR tumors (which have low O6-MT activity and are Mer-), resulted in the regression of the tumors or their disappearance. In animals bearing HeLaS3 tumors (which have high O6-MT activity and are Mer+) the tumors were hyperplastic.
Animals↗