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Biomedical subjects

J Wozniak-Petrofsky

Publications and source records attributed to J Wozniak-Petrofsky.

18 recordsLinked to original sources

Leak point pressures in women with urinary stress incontinence: correlation with patient history.

PURPOSE: We examined the relationship between historical factors in women with urinary stress incontinence and the Valsalva leak point pressure. MATERIALS AND METHODS: Valsalva leak point pressure measurements in 57 women with urinary stress incontinence were compared to findings in the history. RESULTS: Valsalva leak point pressure was low in 83% of women with severe leakage and previous surgery. Interestingly, 47% of patients without predisposing factors had low Valsalva leak point pressures. CONCLUSIONS: Women with severe leakage and previous bladder neck surgery are likely to have urethral dysfunction as demonstrated by Valsalva leak point pressure testing. A significant incidence of low Valsalva leak point pressures in patients without predisposing factors could account for many failures of routine suspension procedures.

Adult↗

Urodynamic tests: client preparation, assessment, and follow-up.

Numerous types of voiding dysfunctions affect patients in all medical and surgical specialties. Recognition, assessment, diagnosis, and treatment or management of voiding dysfunctions have increasingly become the responsibility of many primary health care providers. Urodynamics is a series of neurourologic diagnostic procedures designed to aid in the diagnosis of many types of voiding problems. This article will provide the primary health care provider with a basic but brief review of lower urinary tract function, a fundamental explanation of the urodynamic evaluation and requirements, and a description of the responsibilities of the patient throughout the testing process. Each urodynamic procedure is described separately with the required instrumentation needed for each specific test. This article also will review the responsibilities of the primary health care provider in preprocedural family and patient education, care and preparation, and postprocedural care of the patient referred for a urodynamic evaluation. Additionally, the major indications for a urodynamic workup and etiologies of abnormal findings will be reviewed.

Humans↗

Evaluation of bladder filling.

Urodynamics is the term used for a set of diagnostic tests that measure lower urinary tract function. A variety of tests may be performed, either alone or in combination. Cystometry is the method by which the pressure-volume relationship of the bladder is measured. It is the principal test used to measure bladder filling and storage function. This article discusses the indications and contraindications for the urodynamic evaluation of bladder filling, normal and abnormal findings, and interpretation of findings. In addition, patient preparation, procedural techniques, electromyographic activity during bladder filling and storage, and physiologic events and artifacts are addressed.

Artifacts↗

The nurse's role as investigation coordinator in a drug research study.

In summary, for a smooth running investigational study, the following are essential: 1) clear and concise understanding of the protocol and its criteria, 2) methods for subject recruitment and screening, 3) meetings with all involved ancillary departments and professional staff, 4) development and utilization of time-saving checklists, patient instruction sheets, and other forms, and 5) careful assessment and explicit documentation.

Clinical Protocols↗

Transrectal ultrasonography in prostatic carcinoma.

Transrectal ultrasonography of the prostate is a diagnostic technique allowing visualization of the internal anatomy of the prostate gland, the seminal vesicles, and the prostatic urethra. Although there is still considerable controversy about its reliability, indications for transrectal prostatic ultrasonography include the following: diagnosis of prostate cancer, guidance of transrectal needle biopsies, guidance of staging biopsies, staging previously diagnosed prostate cancers, monitoring treatment response, and assessing glandular size and volume.

Biopsy↗

The safety and efficacy of terazosin for the treatment of benign prostatic hyperplasia.

The efficacy and safety of terazosin was evaluated in 28 normotensive patients with symptomatic benign prostatic hyperplasia (BPH) ranging in age between 52-72 years. The parameters utilized to assess the efficacy of terazosin included peak and mean urinary flow rate, micturition symptom score and the patients' global assessment of symptomatic improvement. The dose of terazosin was titrated to 5 mg/day over a one-month interval, provided significant adverse drug reactions were not observed. Twenty-two (79%) of the 28 patients completed the terazosin dose-titration study, 5 (18%) were withdrawn owing to adverse drug reactions and 1 (3%) was withdrawn owing to poor compliance. Overall, the mean systolic blood pressure, increased 3 mmHg (3%) and the diastolic blood pressure decreased 1 mmHg (1%). The peak and mean urinary flow rates increased 63% and 61%, respectively. The obstructive and irritative symptom scores decreased 62% and 33%, respectively. The improvements in urinary flow rates and symptom scores were clinically and statistically significant. Overall, 61% of the patients indicated that their voiding symptoms were markedly improved on terazosin and 64% of the participants have elected to voluntarily continue on terazosin indefinitely. In conclusion, terazosin represents a safe and effective treatment for symptomatic BPH.

Adrenergic alpha-Antagonists↗