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Biomedical subjects

J Womersley

Publications and source records attributed to J Womersley.

At least 37 records · Page 2Linked to original sources
PubMed1976

Influence of muscular development, obesity, and age on the fat-free mass of adults.

Body fat and the fat-free mass (FFM) were estimated in 36 men and 43 women deliberately chosen to represent a variety of physical types; these were 1) young sedentary, 2) "muscular," 3) younger obese, 4) older obese, and 5) older nonobese individuals of both sexes. The body fat and the FFM were estimated from measurements of body density (by total immersion in water, measurement being made of the residual volume of air present in the lungs at immersion) and from measurements of total body potassium (using a whole-body monitor to assess the natural 40K isotope present in the body). The muscular men and women and the younger obese men and women had a considerably greater FFM and thus had greater quantities of potassium than the corresponding sedentary groups. There were significantly different estimates of the FFM calculated from density and from total body K in three groups, the sedentary young men, the muscular, and the younger obese women. The density and the potassium content of the FFM appear to decline with obesity and aging. Muscular development is associated with a decrease in the density but an increase in the potassium content of the FFM.

Adipose Tissue↗
PubMed1973

The metabolic effects, and the composition of the tissue lost, in weight reduction by obese patients on treatment with fenfluramine.

1. Three groups of obese patients were treated for periods of up to 6 months. One group of 52 individuals received 80-120 mg fenfluramine daily. The second group of 20 people had placebo tablets. The third group of 28 patients were on a dietary restricted régime.2. Only the fenfluramine and dietary treated groups lost weight but there was no evidence of an increased metabolic rate after fenfluramine, either at rest or in standardized exercise. During the first month of treatment the mean weight loss in the group treated with fenfluramine was greater than that in the group treated by diet alone, but the difference was not significant (P<0.05). By the third month of treatment the mean weight loss was smaller in both groups, particularly in the women.3. The composition of the tissue lost in the weight reduction had a mean fat content of 75% and did not differ significantly between the fenfluramine group and the diet-restricted group, except in women.

Adipose Tissue↗