[Therapy of fetal supraventricular tachycardia with esmolol (case report)].
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Biomedical subjects
Publications and source records attributed to J Wisser.
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A rare case of teratoma of the umbilical cord is reported. It is differentiated from acardius amorphus and compared with the nine cases reported in the literature since the first description in 1878. The clinical consequences for pregnancy of the tumour's influence on the circulation are discussed. For the first time, non-radioactive in situ hybridization of the interphase nucleus was performed in a teratoma of the umbilical cord. The results are presented and different histogenetic pathways, e.g. parthenogenetic origin of the teratoma, are debated.
Transvaginal sonographic imaging of the fetal brain performed in the second and third trimester of pregnancy is presented. By this technique coronal and sagittal sections of the central nervous system can be obtained which are similar to those performed via cranial sonography postnatally.
We examined morphologically the placenta in 15 cases of a "vanishing-twin" phenomenon of early pregnancy sonographically confirmed. In 10 of these cases remnants of an additional gestation product could be identified with ample variation in their conservation. These ranged between macerated, but clearly identifiable foetal residues and morphologically regular, empty gestational sacs, all being localised at the placental margin or within the amniotic tissue sheets. The chorionic villi of the surviving twins were normally developed. There was no evidence of any correlation between the developmental status of the vanished twin and any therapeutical intervention, age of the mother or number of initial gestational products. In 3 cases, an intrauterine foetal reduction by foetocide had been performed. In these instances, rather well-developed remnants of the additional fetuses could be found. Since in all cases a pluri-chorionic placenta was present, it is possible, that the vanishing twin phenomenon may be held responsible for an eventual blood group incompatibility during subsequent pregnancies.
Although cytomegalovirus (CMV) can be fatal to patients with the acquired immunodeficiency syndrome (AIDS), it usually causes few, if any, symptoms. The virus has an affinity for the alimentary tract, especially the ileum and right colon. CMV infections of the gut are often erosive, resulting in enterocolitis, hemorrhage, or intestinal perforation. Inflammatory mass formation is rare. Kaposi's sarcoma and lymphoma are established causes of bowel obstruction in patients with AIDS. This report describes a case of ileocecal obstruction due to a discrete CMV-induced pseudotumor in a patient with AIDS.
We report on three cases of acardia, all of which had to be classified as acardius anceps. The degree of cardiac malformation ranged between a completely missing heart and a malrotation of a relatively well-developed heart. One fetus showed an intermediate form of cardiac malformation with a hypoplastic cor triloculare. Our findings suggest that the defect in cardiac development may take place at different times in early embryogenesis, resulting in differing degrees of cardiac malformation.
In multiple pregnancy, an intense supervision of the fetal condition is indicated during pregnancy and delivery. With the aid of a recently developed actocardiograph originally described by Maeda, it is possible to monitor the fetal heart rate (FHR) and fetal movements (FM) of twins simultaneously on one tracing by 2 external Doppler transducers. Additional methods (stimulation, real-time and Doppler ultrasound) were tested in combination with the equipment. In addition, FHR tracings of triplets were registered during delivery simultaneously with FM and contractions. First patterns of "twin behaviour" are described. It may be concluded that this way of recording is of definite practical and potential scientific value.
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Two cases of atypical implantation are presented in order to illustrate the difference between interstitial and intramural pregnancy. Ultrasonography can provide a method of early diagnosis of heterotypic sitting before the occurrence of clinical symptoms. In cases where complications already occurred, sonography can be used to confirm the clinical diagnosis.
375 german departments of obstetrics with a total of 258,348 deliveries answered a questionnaire on the actual standards in obstetrical management for the prevention of neonatal respiratory distress syndrome. On the basis of these extensive data, results could be obtained about the time and the regimen of therapy as well as antenatal diagnostics of lung maturity. Furthermore the results document the treatment of high risk pregnancies like multiple pregnancies, diabetes mellitus, gestosis and PROM.
Gigantomastia complicating pregnancy is rare and of unknown etiology. Medical treatment does not lead to a lasting improvement. We favour surgical treatment, involving plastic reconstructive aspects.
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Maternal convulsions and severe fetal bradycardia resulted from the accidental intravascular injection of 0.5% bupivacaine for epidural anesthesia in preparation for caesarean section. Ventilation with oxygen, application of anticonvulsive drugs, relaxation and intubation was promptly performed followed by immediate caesarean section. The newborn was depressed at birth, recovered quickly and showed no neurologic deficits neither in the immediate postnatal period nor in neurobehaviour tests at the age of three months.
Twenty-eight hours after CO2 insufflation and curettage in a 26 year old, haemolysis, jaundice and anuria developed. As an ectopic pregnancy was also suspected, a diagnostic laparoscopy was done and was followed by a hysterectomy and left salpingo-oophorectomy before Clostridium perfringens was grown on culture. The survival of the patient despite clostridial infection is probably due to immediate surgical treatment and intensive post-operative care.
Between October 1st 1983 and January 31st 1986 we diagnosed various anomalies on 116 foetuses at the Department of Obstetrics and Gynaecology, Klinikum Grosshadern, Munich. In 103 cases we made a correct diagnosis. This group of patients included 45 non-viable foetuses. Severe anomalies of the foetal central nervous system and lethal dwarfism were diagnosed correctly. On the other hand, antenatal diagnosis of bilateral nonfunctional kidneys and non-correctable cardiac malformations poses problems. We feel that in the case of a definitive prenatal diagnosis of an anomaly for which there is no known medical treatment and which is not compatible with life, the decision as to further procedure should be made at this stage. Before 24 weeks gestation, termination of pregnancy on foetal grounds should be discussed with the parents. Thereafter, preterm labour is preferable to the dangers of obstructed labour at term and should be conducted without foetal monitoring.
The case of a 28-year old patient with a rare complication of an extensive endometriosis externa is described. A spontaneous pneumothorax occurred on 3 occasions corresponding each time with the start of the menstrual period. The various hypotheses on the aetiology and treatment of this rare condition are reviewed. To date only 65 patients with this interesting clinical entity have been recorded.