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Biomedical subjects

J Wells

Publications and source records attributed to J Wells.

207 records · Page 12Linked to original sources

The quantitation of triazolam in postmortem blood by gas chromatography/negative ion chemical ionization mass spectrometry.

A specific and sensitive assay has been developed to quantitate triazolam in postmortem blood using 2H6-triazolam as an internal standard. Triazolam is isolated from whole blood by adsorption on an Amberlite XAD-2 resin and subsequent elution with an organic solvent. The extract is analyzed by gas chromatography/mass spectometry using selected ion monitoring (GC/MS/SIM) in the negative chemical ionization mode (Cl-). The procedure is presently being used in case work and the results from 36 cases are presented.

Adult↗

Efficacy of denture cleansing agents in an in vitro bacteria-yeast colonization model.

The purpose of this investigation was to develop a new, in vitro bacteria-yeast denture colonization model. Candida albicans and Streptococcus mutans, organisms associated with denture stomatitis, reproducibly colonized denture blanks in high numbers. Both Efferdent and Super-Strength Polident were able to substantially reduce or eliminate colonizing S mutans. In sharp contrast, however, no significant decreases in adherent C albicans were observed with either denture soaking agent.

Candida albicans↗