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Biomedical subjects

J Weingart

Publications and source records attributed to J Weingart.

At least 37 records · Page 2Linked to original sources
PubMed1984

[Esophageal papilloma--potential precursor of squamous cell carcinoma?].

Endoscopies for various indications revealed a total of 15 papillomas of the oesophagus in 12 patients over a period of 9 months. In most cases they were small whitish prominences in the cervical and thoracic oesophagus. Except for one case only females between 46 and 76 years were affected. Thus papillomas of the oesophagus are more frequent than previously assumed. Virology and histology indicate a potential role of the papilloma as precursor of oesophageal squamous cell carcinoma. Papillomas should thus be excised by loop or forceps.

Aged↗
PubMed1984

[Gastric mucosa heterotopias in the upper gastrointestinal tract].

Heterotopic gastric mucosa does occur in the upper gastrointestinal tract more often than has been thought up to now. Such heterotopic gastric mucosa was systematically looked for in inpatients and outpatients. Islets of heterotopic gastric mucosa were found in 125 patients in the cervical esophagus, in most cases a few centimeters below the esophageal entrance, and in 135 patients such islets of polypoid morphology were found in the duodenal bulbus. Histological analysis done in biopsy specimens taken from the cervical esophagus showed mucosa typical for the gastric corpus in 62 cases, a mixture of glandular tissue from the fundus and mucoid glands in 32 patients, and exclusively mucoid glands in 3 cases. Just superficial mucosa tissue (pits, epithelium) were found in 10 cases, in 14 patients the islets of gastric mucosa were not hit during the biopsy procedure, in 4 cases no biopsy was done. Heterotopic gastric mucosa tissue in the bulbus usually had a diameter of a few millimeters and polypoid morphology; these lesions were located postpylorically in the bulbus and measured more than 5 mm in diameter only in 10 cases. Whereas duodenal heterotopic gastric mucosa probably has no clinical relevance hydrochloric acid producing islets of gastric mucosa in the cervical esophagus may give rise to peptic lesions.

Adult↗
PubMed1983

[Fungus colonization in colitis].

Fungal cultures, unstained smears and histological assessment of endoscopically obtained particles from ulcers in rectum, colon or terminal ileum were obtained in a prospective study of possible fungal infection in 78 patients with colitis of various aetiologies (Crohn's disease - 46; ulcerative colitis - 21; infectious colitis - 5; ischaemic colitis - 2; radiation colitis - 1; non-classifiable colitis - 3). Positive fungal culture was obtained in 13 patients (16.7%). The germ count was low (2--8 colonies per biopsy piece). The demonstrated fungi were almost exclusively Candida or Torulopsis. The potentially pathogenic mycelia phase of the fungi were never seen, either histologically or in unstained preparations. Stool specimens, obtained at the same time, were examined in 54 patients: positive cultures were obtained in 14 (25.9%). Only rarely were there concordance of positive fungal findings in both ulcer particles and faeces. It is concluded that (1) there is little danger of secondary fungal infection in colitis of various aetiologies; (2) positive faecal fungal culture is apparently of no pathogenic significance if the germ count is less than 10(6) per gram stool; (3) in the lower as well as the upper gastro-intestinal tract pathogenic fungal infection can be demonstrated only by endoscopy and biopsy.

Adolescent↗
PubMed1983

[Stenosis endoscope. A new instrument for the diagnosis and therapy of stenoses in the gastrointestinal tract].

A new type of endoscope combines the advantages of the narrow-calibre paediatric endoscopes and the stable-shaft regular endoscopes. This is achieved by reduction of the distal diameter from 13 mm to 9,5 mm with a conical transition between both parts. These characteristics make the instrument particularly suitable for the diagnosis of gastrointestinal stenoses (stenosis endoscope). At the same time the stenosis endoscope dilates as well as a metal olive or a rubber bougie. Thus dilatation of gastrointestinal stenoses is now possible beyond the reach of instruments used as bougie or for dilatation until now. The stenosis endoscope opens new possibilities of therapeutic endoscopy.

Aged↗
PubMed1983

Silver staining of histones in Triton-acid-urea gels.

A reliable method for silver staining histones in Triton-acid-urea gels was developed. Optimum staining is achieved by treating the gels either with amido black or a colorless, water-soluble analog of amido black, 2,7-naphthalenedisulfonic acid, prior to staining with ammoniacal silver. Staining of purified calf thymus histones H2A, H2B, H3, and H4 by this method is 30 times more sensitive than staining with amido black alone, allowing the detection of each histone and its modified forms down to the nanogram level. The use of 2,7-naphthalenedisulfonic acid dramatically shortens the procedure permitting histone patterns to be visualized within 5 h.

Acetates↗
PubMed1982

Percutaneous decompression of an intraintestinal balloon--case report.

A study was designed in order to determine whether waterfilled intragastric balloons are superior to airfilled balloons for facilitating weight reduction. In the first volunteer the small intestine was obstructed by the dislocated waterfilled balloon. This complication was successfully treated by transabdominal fine needle puncture of the balloon. In contrast to airfilled balloons waterfilled balloons offer two advantages: water does not escape through the very thin wall of the balloon; the intraabdominal location of a waterfilled balloon is easily checked by sonography.

Gastroenterology↗
PubMed1981

[Calcium-containing antacids in the therapy of duodenal ulcers].

The neutralization of acid by antacids and the inhibition of acid secretion by H2-receptor antagonists are the two essential factors in the standard therapy for peptic ulcer disease. In order to determine whether a high dosage therapy with a calcium-containing antacid accelerates the healing of the ulcer or retards it through the "Acid-rebound" effect of the calcium, we examined in a clinical study 10 patients with an endoscopically proven duodenal ulcer. After 2 weeks the duodenal ulcer was healed in 5 of the 10 patients. Thus a rate of healing was attained which was achieved in our clinic with a daily dosage of 1200 mg or 800 mg of cimetidine or with a Mg/Al-hydroxide-containing antacid in a daily dosage of 560 mval neutralization capacity in duodenal ulcer patients. On the other hand there was a difference in the healing of the ulcer between the methods of treatment presented and the exclusive dose of a placebo.

Antacids↗