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Biomedical subjects

J Wehnert

Publications and source records attributed to J Wehnert.

At least 37 records · Page 2Linked to original sources
PubMed1981

[Therapy of detrusor hyperactivity with propiverin (mictonorm)].

In the context of treating hyperactivity of the detrusor the newly developed preparation Propiverin (Mictonorm) is presented. It is postganglionic and anticholinergic and mainly acts peripherally and selectively on the bladder. At the same time a musculotropic relaxing effect with a specific affinity to the unstriated musculature of the bladder can be demonstrated in experiments on animals. In our urodynamic investigations the application of the medicament resulted in an increase in bladder capacity, a reduction of urge symptoms, a decrease in bladder tension and a depression of the uroflow. These results justify the clinical use of Propiverin after appropriate urodynamic diagnostic checks.

Benzilates↗
PubMed1980

New technical possibilities for simultaneous cystometry.

With the introduction of integrated semiconductor pressure pick-ups into the urodynamic methodology of analysis, the bladder and urethral manometry has been optimized, since the measuring transducer is positioned directly inside the lumen of the bladder. In this way, it is possible to eliminate the errors of conventional measuring methods with the liquid-filled or gas-filled catheter system, for example movements, vibrations, hydrostatic influences on the coupling medium by different vertical positions of the catheter or connecting tube, as well as cloggings due to haematuria or secretion of mucus. Owing to its dimensions and radiopaque properties, the IBW 78 tip manometer is suitable also for the pressure measurement in the upper urinary passages including the pyelon. The pressure signals obtained are further processed in a special plug-in unit for the biomonitor system, and thus they can be recorded on any multiple recorder.

Humans↗
PubMed1980

[On clinical and differential diagnosis of primary ureteral tumors].

Primary tumours of the ureter are to be regarded as rare tumours. Etiopathogenesis, pathology and clinic are discussed, taking into consideration own experiences. The authors cannot subscribe to the widespread view of operating primary solitary tumours of the ureter on principle only radically in form of the nephroureterectomy. A differentiated, individual approach with a primarily conservative-reconstructive orientation is recommended.

Diagnosis, Differential↗
PubMed1979

[New technical possibilities for simultaneous cystometry].

With the introduction of integrated semiconductor pressure admitters into the urodynamic examination methodology an optimization of the manometry of the bladder and the urethra was carried out, since the changer of the measuring value in this case is directly situated in the lumen of the bladder. Thus it is achieved that the possibilities of errors which are connected with the conventional measuring method with the catheter system filled with fluid or gas, such as movements, concussions, hydrostatic influence of the coupling medium by different altitude level of the catheter and the connection tube, respectively, but also constipations in haematuria or excretions of the mucus may be excluded. The presented tip manometre IBW 74 due to its measures and radiopaque properties is also suited for the measurement of the pressure on the upper urinary tracts including the pyelon. Hereby the pressure signals gained are further elaborated through a special insertion for the biomonitor system and thus may be recorded on every multiple recorder.

Elasticity↗
PubMed1979

[Effect of anticholinergics on bladder tonus and on the voiding function].

When the anticholinergic drugs with an effect which above all peripherally and selectively affects the urinary bladder the following may be proved: 1. Increase of the capacity of the urinary bladder according to the initial situation, 2. no influence on the intravesical pressure in maximum filling of the bladder, 3. decrease of the maximum intravesical pressure during the miction, 4. decrease of the rate of the flow of the urine and 5. increase of the maximum urethral pressure as well as no influence on the functional length of the urethra. From these parameters the adequate clinical application in diseases of the urinary bladder may be derived and at a strong indication good successes in treatment can be achieved.

Adult↗
PubMed1979

[The value of the urethral pressure profile in urinary incontinence].

For the differentiation of the incontinence the tonometry of bladder and urethra has become indispensable in diagnostics. The author deals with the advantages of the possibility of a combined examination, the technical performance of the urethra-pressure profile and with the necessity of the same outer conditions. Taking into consideration the functional length of the urethra, the maximum pressure of the urethra as well as the difference between pressure of urinary bladder and urethra in rest and under conditions of stress the criteria for the degrees of incontinence are represented and discussed on the basis of own examinations. Not the position and the absolute length are responsible for the continence, but the relation between the attainable urethra-pressure in contrast to the appearing pressure of the urinary bladder.

Cough↗
PubMed1978

[Uroflowmetry and its methodology. Normal limits. II. Normal range].

Prerequisite for every evaluation of a uroflowmetry curve are normal regions, on which the diagnostic evidence of the examination method is based. In the present paper a definite attitude to the limits of the normal was adopted, in which case apart from the course of the curve the relations from maximum flow to miction volume were entered. Diagrams of the normal region were established for men, women, and children, in which cases apart from the interindividual diffusion breadth also the individual diffusion breadth was taken into consideration. Error in the diagnostic course develop always then, when only mean values are taken into consideration. The critical consideration of the normal values to age seems to be important, in which cases a peak of the maximum values of the urinary flow is to be established between the 13th and the 40th year. In the later decades of life also without any subvesical obstruction an exponential function similar decrease of the maximum values of the flow develops.

Adolescent↗
PubMed1978

[Uroflowmetry and its methodology for establishment of urinary flow parameters. I].

In the present paper the author deals in a short form with the importance of the uroflowmetry as a functional examination method. Prerequisite for every documentation of the picture of the miction curve is the diagram of the urinary flow. Here only the direct curve of the flow is suited for the immediate readability of the adequate values as well as for the simultaneous recognition. For the superficial orientation about the course of the flow the control of the curve is enough, but for the differentiated evaluation the following factors must be taken into consideration: Time of flow, time of waiting, different and maximum urinary flow, increase of the curve of the urinary flow and number of the peaks of flow. Also the differentiating uroflowmetry should be taken into consideration, in order to separate neurogenic disturbances of the urinary bladder from obstructive changes of the vesical outlet in the screening method.

Diagnosis, Differential↗