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Biomedical subjects

J Walker

Publications and source records attributed to J Walker.

At least 487 records · Page 27Linked to original sources
PubMed1973

Mutants of nonproducer cell lines transformed by murine sarcoma viruses. I. Induction, isolation, particle production, and tumorigenicity.

A variety of cell mutants were obtained by a single 5'-bromodeoxyuridine (BrdU) treatment of an nonproducer (NP) cell line transformed by the Kirsten strain of murine sarcoma virus (Ki-MSV). Isolation procedures of these cell See PDF for Structure mutants are described. The cell mutants obtained were classified by tumorigenic potential and shedding of Type C virus particles. The cell mutants were classified into four groups: (A) tumorigenic, without particles; (B) tumorigenic, with Type C particles; (C) nontumorigenic, without particles; and (D) nontumorigenic, with Type C particles. The tumorigenic cell lines showed variability in morphology with both flat and typical transformed appearing cell lines showing equal transplantability.

Animals↗
PubMed1973

Action of adenosine triphosphate on endplate potentials recorded from muscle fibres of the rat-diaphragm and frog sartorius.

Evoked and spontaneous endplate potentials (e.p.ps) were recorded with intracellular electrodes from fibres of the rat diaphragm and the frog sartorius muscle. The amplitudes of the evoked e.p.ps were reduced to about one-half their control values in the presence of 0.1 mm and 0.2 mm of adenosine triphosphate (ATP). The amplitude of the spontaneous endplate potentials (miniature e.p.ps) was unaffected by ATP but their frequency was reduced.

Adenosine Triphosphate↗